Research keywords (2)：
Biosynthesis
, Natural Product Chemistry
Research theme for competitive and other funds (6)：
2022 - 2027 Enhancing the diversity of peptides by amino acids with reactive functional groups
2022 - 2027 Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.
2023 - 2026 生理活性天然物の生合成に関わる三員環構築酵素の精密解析
2018 - 2021 Analysis of new peptide epimerases for the biosynthesis of peptide natural products
2016 - 2018 Exploring and functional analysis of peptide ligase orthologs
2015 - 2018 Biosynthesis of the Carbonylmethylene Structure Found in a Class of Pseudotripeptides, Ketomemicins
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Papers (60)：
Ning Shen, Yasuharu Satoh, Daisuke Koma, Hiroyuki Ohashi, Yasushi Ogasawara, Tohru Dairi. Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli. Journal of Bioscience and Bioengineering. 2024. 137. 2. 115-123
Shuhei Umetsu, Takeshi Tsunoda, Haruka Kiyanagi, Yuki Inahashi, Kenichi Nonaka, Tohru Dairi, Yasushi Ogasawara. Identification of a new oligomycin derivative as a specific inhibitor of the alternative peptidoglycan biosynthetic pathway. The Journal of antibiotics. 2024
Wanlu Xiao, Takeshi Tsunoda, Chitose Maruyama, Yoshimitsu Hamano, Yasushi Ogasawara, Tohru Dairi. Peptide epimerase-dehydratase complex responsible for biosynthesis of the linaridin class ribosomal peptides. Bioscience, biotechnology, and biochemistry. 2023. 87. 11. 1316-1322
Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo, Kuan-Hung Lin, Chun-Liang Chen, Chi-Fon Chang, Zhe-Chong Wang, Yasushi Ogasawara, Tohru Dairi, et al. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nature communications. 2023. 14. 1. 2528-2528
梅津秀平, 角田毅, 稲橋佑起, 野中健一, 小笠原泰志, 大利徹. Searching for Specific Inhibitors of the Alternative Pathway of Peptidoglycan Biosynthesis. 日本放線菌学会大会講演要旨集. 2023. 37th
2021/01 - 現在 Hokkaido University Faculty of Engineering Associate Professor
2014/04 - 2020/12 Hokkaido University Faculty of Engineering
2013/01 - 2014/03 The University of New Mexico Department of Chemistry and Chemical Biology Research Assistant Professor
Committee career (1)：
2023/04 - 現在 Japan Society for Bioscience, Biotechnology, and Agrochemistry -
Awards (4)：
2021/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry Hot Topics Award Epimerase involved in polyglutamic acid biosynthesis
2019/03 - 日本農芸化学会 トピックス賞 in vitro解析による多価不飽和脂肪酸生合成酵素の炭素鎖長制御機構の解明
2018/03 - 日本農芸化学会 奨励賞 ペプチドの構造に多様性を与える新規酵素の探索
2017/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry Hot Topics Award An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis
Association Membership(s) (3)：
The Society for Biotechnology, Japan
, SOCIETY FOR ACTINOMYCETES JAPAN
, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
