Research theme for competitive and other funds (10):
2023 - 2025 糸状菌由来新規酸化酵素ファミリーの機能開拓
2022 - 2025 ゲノムマイニングによる糸状菌由来ペプチド系天然物の開拓
2019 - 2022 Exploring new biologically active metabolites using unidentified gene clusters from Basidiomycota genomes
2019 - 2022 Studies on the biosyntheses of fungal dimeric anhydrides
2019 - 2021 植物病原菌が生産するペプチド系化合物の構造多様性創出機構の解析
2017 - 2019 麹菌異種発現系を用いた感染時特異的な糸状菌代謝産物の安定供給
2017 - 2019 糸状菌リボソームペプチドの生合成に普遍的な新規環化酵素の機能解明
2014 - 2015 Studies on the mechanism of action of goadsporin and generation of new derivatives
2013 - 2013 Studies on the mechanism for goadsporin resistance
2010 - 2012 新規プレニル基転移酵素の機能解析と有用化合物創製への応用
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Papers (59):
Yoshiro Sato, Xinge Shi, Ying Ye, Saori Domon, Junya Takino, Taro Ozaki, Chengwei Liu, Hideaki Oikawa, Atsushi Minami. Bioinformatics-Guided Reconstitution of Biosynthetic Machineries of Fungal Eremophilane Sesquiterpenes. ACS Chemical Biology. 2024
Fumito Sato, Terutaka Sonohara, Shunta Fujiki, Akihiro Sugawara, Yohei Morishita, Taro Ozaki, Teigo Asai. Genome mining of labdane-related diterpenoids: Discovery of the two-enzyme pathway leading to (-)-sandaracopimaradiene in the fungus Arthrinium sacchari. Beilstein Journal of Organic Chemistry. 2024
Yue Shi, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Yu Pei Tan, Roger G. Shivas, Rohan A. Davis, Teigo Asai. A new 3,6-dialkyl-α-pyrone produced by the heterologous expression of a PKS-NRPS hybrid enzyme derived from a Pestalotiopsis endophyte. Tetrahedron Letters. 2024
Mitsunori Fukaya, Shota Nagamine, Taro Ozaki, Yaping Liu, Miina Ozeki, Taro Matsuyama, Kazunori Miyamoto, Hirokazu Kawagishi, Masanobu Uchiyama, Hideaki Oikawa, et al. Total Biosynthesis of Melleolides from Basidiomycota Fungi: Mechanistic Analysis of the Multi-Functional GMC Oxidase Mld7. Angewandte Chemie (International ed. in English). 2023. e202308881
Taro Ozaki. Structural diversification of fungal natural products by oxidative enzymes. Bioscience, biotechnology, and biochemistry. 2023. 87. 8. 809-818
2021/09 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences
2016/04 - 2021/08 Hokkaido University Faculty of Science Department of Chemistry Assistant Progessor
2013/04 - 2016/03 The University of Tokyo
2010/04 - 2013/03 日本学術振興会 特別研究員(DC1)
Awards (3):
2023/03 - The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry Structure and biosynthesis of the ribosomal lipopeptide antibiotic albopeptins
2020/03 - The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase
Association Membership(s) (5):
日本生薬学会
, THE CHEMICAL SOCIETY OF JAPAN
, SOCIETY OF ACTINOMYCETES JAPAN
, JAPAN SOCIETY FOR BIOSICENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
, 日本薬学会