Research field (1)：
Pharmaceuticals - analytical and physicochemistry
Research theme for competitive and other funds (13)：
2023 - 2026 Development of novel nanobubbles composed of antibody drugs and ultrasound contrast gas and their potential applications
2021 - 2024 Development of ultrasound-responsive nanobubbles specialized on heart failure and construction of a disease treatment system
2020 - 2023 Development of CO2 generating nanoparticles for pancreatic cancer theranostics
2019 - 2022 Development of novel theranostics system using photoacoustic and ultrasound-responsive nanobubbles
2018 - 2020 Development of cancer theranostics systems using CO2-generating nanoparticles and ultrasound
2016 - 2019 Development of antibody delivery system by ultrasound responsive nano bubble and breast cancer treatment strategy
2015 - 2018 Ultrasensitive MRI detection of spontaneous pancreatic tumors with nanocage-based targeted contrast agent
2015 - 2018 Biodegradable nano-cages for controlled drug release
2014 - 2016 Development of brain tissue targeting dual-imaging capsule
2012 - 2015 Protein Nanocages-Conjugated Magnetic Resonance Contrast Agents Displaying High Relaxivity and Tumor Selectivity.
2013 - 2014 Pancreatic cancer specific targeting by protein nanocages
2011 - 2014 Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasound
2008 - 2010 Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gas
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Papers (38)：
Yusuke Yano, Rui Tada, Nobuhito Hamano, Kenshin Haruta, Tomomi Kobayashi, Masahiro Sato, Yamato Kikkawa, Yoko Endo-Takahashi, Motoyoshi Nomizu, Yoichi Negishi. Development of a concise and reliable method for quantifying the antibody loaded onto lipid nanoparticles modified with Herceptin. Journal of Immunological Methods. 2023. 521. 113554-113554
Shohko Sekine, Sayaka Mayama, Nobuaki Nishijima, Takuo Kojima, Yoko Endo-Takahashi, Yuko Ishii, Hitomi Shiono, Saki Akiyama, Akane Sakurai, Sanae Sashida, et al. Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound. Pharmaceutics. 2023. 15. 6. 1665
Yusuke Yano, Nobuhito Hamano, Kenshin Haruta, Tomomi Kobayashi, Masahiro Sato, Yamato Kikkawa, Yoko Endo-Takahashi, Rui Tada, Ryo Suzuki, Kazuo Maruyama, et al. Development of an Antibody Delivery Method for Cancer Treatment by Combining Ultrasound with Therapeutic Antibody-Modified Nanobubbles Using Fc-Binding Polypeptide. Pharmaceutics. 2022. 15. 1. 130-130
Yoko Endo-Takahashi, Ryo Kurokawa, Kanako Sato, Nao Takizawa, Fumihiko Katagiri, Nobuhito Hamano, Ryo Suzuki, Kazuo Maruyama, Motoyoshi Nomizu, Norio Takagi, et al. Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound. Pharmaceutics. 2021. 13. 7
Ultrasound-mediated drug delivery in the combination with micro- and nanobubbles. Drug delivery system : DDS : official journal of the Japan Society of Drug Delivery System. 2021. 36. 3. 166-174
2022/04 - 現在 Tokyo University of Pharmacy and Life Sciences, School of Pharmacy Department of Formulation Science and Technology Senior Assistant Professor
2019/10 - 2022/03 Tokyo University of Pharmacy and Life Sciences, School of Pharmacy Department of Drug Delivery and Molecular Biopharmaceutics Assistant Professor
2018/04 - 2019/09 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
2018/03 - 2018/04 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
2016/02 - 2018/02 The University of British Columbia Faculty of Pharmaceustical Sciences Postdoctoral Research Fellow
2013/04 - 2016/02 九州大学先端医療イノベーションセンター 特任助教
2010/04 - 2013/03 Tokyo University of Pharmacy and Life Sciences
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Awards (5)：
2017/09 - Vancouver Nanomedicine Day 2017 Poster prize (1st)
2016/12 - 上原記念生命科学財団 海外留学助成金 リサーチフェローシップ
2014/07 - 第30回日本DDS学会 優秀発表者賞 (ポスター部門)
2012/07 - 第28回日本DDS学会 優秀発表者賞
2012/05 - Joint Congress of Medical Ultrasound in Seoul Best Poster Award (Bronze)
Association Membership(s) (3)：
THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN
, THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM
, THE PHARMACEUTICAL SOCIETY OF JAPAN
