Ninagawa Satoshi

Affiliation and department：
Job title： Assistant Professor
Other affiliations (1)：

Kobe University Graduate School of Agricultural Science Department of Bioresource Science Assistant Professor

Homepage URL (1)： http://www2.kobe-u.ac.jp/~ninagawa/

Research field (3)： Zoological sciences , Applied molecular and cellular biology , Cell biology

Research keywords (4)： Protein quality control , mannose trimming , EDEM , ER associated degradation

Research theme for competitive and other funds (6)：

2022 - 2025 哺乳動物の小胞体関連分解における小胞体内イベントの全容解明
2017 - 2022 Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
2018 - 2021 Analysis of how misfolded proteins are delivered to retrotranslocation complex for ER-associated degradation
2016 - 2018 Insight into how severely misfolded proteins are degraded in the ER
2014 - 2016 Analysis of ER-associated degradation components by multiple knockout cell lines using TALEN

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Papers (23)：

Satoshi Ninagawa, Masaki Matsuo, Deng Ying, Shinya Aso, Kazutoshi Matsushita, Akane Fueki, Shunsuke Saito, Koshi Imami, Yasuhiko Kizuka, Tetsushi Sakuma, et al. UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins. 2023
Tomoyo Ikeda, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Masaya Ono, Kazutoshi Mori. Proteomic analysis of fatty liver induced by starvation of medaka fish larvae. Cell structure and function. 2023. 48. 2. 123-133
Shengyu Jin, Byungseok Jin, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Sho Koyasu, Hiroshi Harada, Kazutoshi Mori. Loss of ATF6α in a Human Carcinoma Cell Line Is Compensated not by Its Paralogue ATF6β but by Sustained Activation of the IRE1 and PERK Arms for Tumor Growth in Nude Mice. Molecular Biology of the Cell. 2023
Shunsuke Saito, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Kazutoshi Mori. A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b. eLife. 2022. 11
Ginto George, Satoshi Ninagawa, Hirokazu Yagi, Jun-Ichi Furukawa, Noritaka Hashii, Akiko Ishii-Watabe, Ying Deng, Kazutoshi Matsushita, Tokiro Ishikawa, Yugoviandi P Mamahit, et al. Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. eLife. 2021. 10

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MISC (32)：

蜷川暁, 蜷川暁, 松尾將生, DENG Ying, 阿曽伸哉, 松下和俊, 笛木茜, 斎藤俊介, 今見考志, 木塚康彦, et al. UGGTs prevent premature degradation of unstable and misfolded glycoproteins in the endoplasmic reticulum. 日本糖質学会年会要旨集. 2023. 42nd
笛木茜, 津曲和哉, 松尾將生, 今見考志, 蜷川暁, 蜷川暁. Effects of the endoplasmic reticulum folding sensor UGGT on secretion. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
松尾將生, DENG Ying, 矢木宏和, 矢木宏和, 津曲和哉, 笛木茜, 今見考志, 加藤晃一, 加藤晃一, 加藤晃一, et al. UGGTs affect not only glycoprotein folding but also degradation. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
蜷川暁. 小胞体におけるN型糖鎖による糖タンパク質の品質管理機構. Trends in glycoscience and glycotechnology. 2021. 33. 191-193. J55-62
蜷川暁. N-glycan Dependent Protein Quality Control System in the Endoplasmic Reticulum. Trends in Glycoscience and Glycotechnology (Web). 2021. 33. 193

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Education (4)：

Work history (5)：

2021/10 - 現在 Graduate School of Agricultural Sciences, Kobe University Department of Applied Chemistry in Bioscience Assistant Professor
2021/10 - 現在 Kobe University Biosignal Research Center
2015/07 - 2021/09 京都大学大学院理学研究科
2014/04 - 2015/06 自然科学研究機構岡崎統合バイオサイエンスセンター
2005/04 - 2014/03 -

Awards (6)：

2023/04 - 長瀬研究振興賞
2020 - 日本糖質学会日本糖質学会奨励賞高等動物におけるN 型糖鎖のマンノース切除を基軸とした小胞体関連分解機構の解析
2020 - 日本生化学会日本生化学会奨励賞遺伝子破壊法を用いた小胞体関連分解機構の解明
2017 - CSF award SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation
2016/06 - 日本細胞生物学会若手優秀発表賞分解執行局域における新展開

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Association Membership(s) (4)：

日本糖質学会 , 日本細胞生物学会 , 日本分子生物学会 , 日本生化学会

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