Somiya Masaharu

ソミヤマサハル | Somiya Masaharu

Affiliation and department：
Job title： Associate Professor
Homepage URL (2)： https://masaharusomiya.page/ja/ , https://masaharusomiya.page/en/

Research field (4)： Molecular biochemistry , Structural biochemistry , Nanobioscience , Biomaterials

Research keywords (8)： Protein design , 細胞外小胞 , 合成生物学 , liposome , Nucleic acid medicines , Hepatitis B virus , Exosomes , Drug delivery systems

Research theme for competitive and other funds (11)：

2024 - 2028 生体膜融合の操作によって新機能を創発するデザイナー細胞の開発
2020 - 2022 Deciphering the intercellular signaling via extracellular vesicles by lipid-recognizing GPCRs
2016 - 2021 Development of Neo-bionanocapsule for Various In Vivo Targets
2018 - 2020 mRNA sorting into exosomes and its application for drug delivery
2017 - 2020 Cancer therapy utilizing nucleic acid-encapsulating exosomes that target tumor-associated macrophages

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Papers (52)：

Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, et al. Computational design of non-porous pH-responsive antibody nanoparticles. Nature structural & molecular biology. 2024
Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O'Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, et al. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles. 2024. 13. 2
Erin C. Yang, Robby Divine, Marcos C. Miranda, Andrew J. Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, et al. Computational design of non-porous, pH-responsive antibody nanoparticles. 2023
Hideaki Fujita, Seiichi Ohta, Noriko Nakamura, Masaharu Somiya, Masanobu Horie. Progress of Endogenous and Exogenous Nanoparticles for Cancer Therapy and Diagnostics. Genes. 2023. 14. 2. 259-259
Masanobu Horie, Noriko Yamano-Adachi, Yoshinori Kawabe, Hidenori Kaneoka, Hideaki Fujita, Eiji Nagamori, Ryosuke Iwai, Yasushi Sato, Kei Kanie, Seiichi Ohta, et al. Recent advances in animal cell technologies for industrial and medical applications. Journal of bioscience and bioengineering. 2022. 133. 6. 509-514

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MISC (4)：

Development of Drug Delivery System Nanocarrier by Biomimicking Technology : Bio-Nanocapsule Based on Hepatitis B Virus Early Infection Machinery. 2016. 45. 11. 18-24
Liu Qiushi, Somiya Masaharu, Kuroda Shun'ichi. 3P-223 Generation of Hepatitis B Virus Envelope L Particle-derived Virosomes Containing Doxorubicin. 2015. 67. 326-326
Yamaguchi Kotomi, Somiya Masaharu, Kuroda Shun'ichi. 3P-239 Non-cationic bio-nanocapsule-based nanocarrier for siRNA delivery. 2014. 66. 254-254
Yokoi Sakiho, Somiya Masaharu, Matsuo Hidenori, Kuroda Shun'ichi. 3P-240 Dendritic cell-specific antigen delivery by bio-nanocapsule-liposome complex. 2014. 66. 254-254

Patents (1)：

核酸を内封してなる中性又はアニオン性リポソーム及びその製造方法。

Lectures and oral presentations (12)：

3P-223 Generation of Hepatitis B Virus Envelope L Particle-derived Virosomes Containing Doxorubicin
(日本生物工学会大会講演要旨集 2015)
B型肝炎ウイルスの感染機構を模倣したバイオナノカプセル-リポソーム複合体のエンドソーム脱出機構の解明
(日本DDS学会学術集会プログラム予稿集 2015)
B型肝炎ウイルスの感染機構を搭載したDDSナノキャリアのがん治療への応用
(日本薬学会年会要旨集(CD-ROM) 2015)
3P-240 Dendritic cell-specific antigen delivery by bio-nanocapsule-liposome complex
(日本生物工学会大会講演要旨集 2014)
3P-239 Non-cationic bio-nanocapsule-based nanocarrier for siRNA delivery
(日本生物工学会大会講演要旨集 2014)

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Education (4)：

2011 - 2016 Nagoya University Graduate School of Bioagricultural Sciences
2014 - 2014 Massachusetts Institute of Technology Department of Chemical Engineering
2009 - 2011 Kitakyushu National College of Technology Advanced Engineering School
2004 - 2009 Kitakyushu National College of Technology Department of Materials Science & Chemical Engineering

Professional career (1)：

Doctor of Agriculture (Nagoya University)

Work history (8)：

2024/06 - 現在 Osaka University SANKEN Associate Professor
2017/06 - 2024/05 Osaka University The Institute of Scientific and Industrial Research Assistant Professor
2022/02 - 2024/02 Japan Society for the Promotion of Science Overseas Research Fellowship
2022/02 - 2024/02 University of Washington Institute for Protein Design Visiting Scholar (Neil King lab)
2017/04 - 2017/05 National Cancer Center Research Institute Division of Molecular and Cellular Medicine Visiting researcher

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Committee career (3)：

2021/10 - 現在日本生物工学会生物工学若手研究者の集い(生物工学若手会) 役員(会計)
2018/04 - 現在日本生物工学会次世代アニマルセルインダストリー研究部会運営委員(HP&メーリングリスト担当)
2019/09 - 2021/10 日本生物工学会生物工学若手研究者の集い(生物工学若手会) 役員(ホームページ・フォーラム担当)

Awards (10)：

2021/05 - International Society for Extracellular Vesicles Scholarship for ISEV2021 Reporter gene assay for membrane fusion and cytoplasmic cargo delivery of extracellular vesicles
2020/10 - 日本細胞外小胞学会JSEV 第7回日本細胞外小胞学会学術集会奨励賞細胞外小胞のレシピエント細胞内での内包物放出を定量化するアッセイ系の開発
2018/06 - AMED and NYAS Outstanding Team Presentation at Interstellar Initiative 2018 Workshop Discovery of Novel Therapeutics in Kidney Cancer
2017/12 - 公益財団法人川崎市産業振興財団 Poster Presentation Award Bioavailability of bovine milk-derived exosome for drug delivery application
2017/09 - 日本RNAi研究会・日本細胞外小胞学会 Oral Presentation Award 牛乳由来細胞外小胞のドラッグデリバリーシステムへの応用

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Association Membership(s) (6)：

International Society for Extracellular Vesicles , The Society for Biotechnology, Japan , THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM , 日本細胞生物学会 , 日本生物物理学会 , Japanese Society for Extracellular Vesicles

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