Research theme for competitive and other funds (3)：
2014 - 2016 Evaluation of animal-free systems in human deatal pulp cells using a spinal cord injury model
2010 - 2012 Establishment of an animal-free systems for human dental pulp-derived stem cell culture and induction of iPS cells
2008 - 2009 The improvement of establishment efficiency and the induction to iPS cells of human dental pulp stem cells
Papers (6)：
Hidefumi Fukumitsu, Hitomi Soumiya, Kaito Nakamura, Kosuke Nagashima, Makoto Yamada, Hiroyuki Kobayashi, Takahiro Miwa, Atsuki Tsunoda, Tomoko Takeda-Kawaguchi, Ken-Ichi Tezuka, et al. Effects of FGF2 Priming and Nrf2 Activation on the Antioxidant Activity of Several Human Dental Pulp Cell Clones Derived From Distinct Donors, and Therapeutic Effects of Transplantation on Rodents With Spinal Cord Injury. Cell transplantation. 2024. 33. 9636897241264979-9636897241264979
Yuta Shimizu, Tomoko Takeda-Kawaguchi, Izumi Kuroda, Yasuaki Hotta, Hideya Kawasaki, Takahiko Hariyama, Toshiyuki Shibata, Yukihiro Akao, Takahiro Kunisada, Junichi Tatsumi, et al. Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis. Journal of Periodontal Research. 2021. 57. 1. 162-172
Sugiyama K, Nagashima K, Miwa T, Shimizu Y, Kawaguchi T, Iida K, Tamaoki N, Hatakeyama D, Aoki H, Abe C, et al. FGF2-responsive genes in human dental pulp cells assessed using a rat spinal cord injury model. Journal of bone and mineral metabolism. 2018
Kosuke Nagashima, Takahiro Miwa, Hitomi Soumiya, Daisuke Ushiro, Tomoko Takeda-Kawaguchi, Naritaka Tamaoki, Saho Ishiguro, Yumi Sato, Kei Miyamoto, Takatoshi Ohno, et al. Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury. SCIENTIFIC REPORTS. 2017. 7. 1. 13500
Kato Hiroki, Kanematsu Masayuki, Toida Makoto, Kawaguchi Tomoko, Shibata Toshiyuki, Kajita Kimihiro, Hoshi Hiroaki. Salivary gland function evaluated by diffusion-weighted MR imaging with gustatory stimulation: preliminary results. Journal of magnetic resonance imaging : JMRI. 2011. 34. 4. 904-909
T. Takeda-Kawaguchi, K. Sugiyama, S. Chikusa, K. Iida, H. Aoki, N. Tamaoki. Derivation of iPSCs after Culture of Human Dental Pulp Cells under Defined Conditions (Vol 9, e115392, 2014). PLOS ONE. 2015. 10. 3
