Inagaki Tadakatsu

イナガキタダカツ | Inagaki Tadakatsu

Research field (1)： Physiology

Research theme for competitive and other funds (8)：

2022 - 2025 炎症シグナルによる肺動脈性肺高血圧症の発症機構解明に向けた基盤的研究
2021 - 2024 肺高血圧症におけるgp130依存性サイトカインシグナルの役割の解明
2019 - 2022 Fundamental research for the development of a new strategy for the treatment of severe pulmonary hypertension by IL-6 blockade
2017 - 2019 Development of a treatment for pulmonary arterial hypertension focusing on inflammatory endothelial dysfunction
2016 - 2018 Synchrotron radiation investigation of cardiac contractile protein dynamics at end diastole in a type 2 prediabetes model rat

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Papers (31)：

Tadakatsu Inagaki, James T. Pearson, Hirotsugu Tsuchimochi, Daryl O. Schwenke, Shigeyoshi Saito, Takahiro Higuchi, Takeshi Masaki, Keiji Umetani, Mikiyasu Shirai, Yoshikazu Nakaoka. Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography. American Journal of Physiology-Heart and Circulatory Physiology. 2021. 320. 3. H1021-H1036
James T Pearson, Hamish P Thambyah, Mark T Waddingham, Tadakatsu Inagaki, Vijayakumar Sukumaran, Jennifer P Ngo, Connie P C Ow, Takashi Sonobe, Yi Ching Chen, Amanda J Edgley, et al. β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto-Kakizaki rat. Clinical science (London, England : 1979). 2021. 135. 2. 327-346
James Pearson, Hamish P Thambyah, Mark T Waddingham, Tadakatsu Inagaki, Vijayakumar Sukumaran, Jennifer P Ngo, Connie Pc Ow, Takashi Sonobe, Yi Ching Chen, Amanda J Edgley, et al. Beta-blockade Prevents Coronary Macro and Microvascular Dysfunction Induced by a High Salt Diet and Insulin Resistance in the Goto-Kakizaki Rat. Clinical science (London, England : 1979). 2021
Tadakatsu Inagaki, Hirotsugu Tsuchimochi, James T. Pearson, Daryl O. Schwenke, Keiji Umetani, Mikiyasu Shirai, Yoshikazu Nakaoka. Impaired right coronary vasodilator function in pulmonary hypertensive rats assessed by in vivo synchrotron microangiography. Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension. 2020. 193-195
Hikari Takeshita, Koichi Yamamoto, Satoko Nozato, Masao Takeda, So-Ichiro Fukada, Tadakatsu Inagaki, Hirotsugu Tsuchimochi, Mikiyasu Shirai, Yoichi Nozato, Taku Fujimoto, et al. Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice. Journal of cachexia, sarcopenia and muscle. 2018. 9. 5. 975-986

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MISC (7)：

Cheng-Kun Du, Dong-Yun Zhan, Tsuyoshi Akiyama, Takashi Sonobe, Tadakatsu Inagaki, Mikiyasu Shirai. Myocardial Interstitial Serotonin and its Major Metabolite, 5-Hydroxyindole Acetic Acid Levels Determined by Microdialysis Technique in vivo Rat Heart. BIOPHYSICAL JOURNAL. 2015. 108. 2. 595A-596A
山越康平, 柳下和慶, 土持裕胤, 稲垣薫克, 白井幹康, 狩野豊. 高気圧酸素曝露に対する糖尿病の循環調節機構. 体力科学. 2014. 63. 6. 642-642
Cheng-Kun Du, Dong-Yun Zhan, Tsuyoshi Akiyama, Tadakatsu Inagaki, Mikiyasu Shirai. Myocardial interstitial serotonin (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) levels during ischemia-reperfusion. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 193P-193P
Tadakatsu Inagaki, Hirotsugu Tsuchimochi, Tomoe Y. Nishitani-Nakamura, Shigeo Wakabayashi, Mikiyasu Shirai. The role of NCS-1 in the development of right ventricular hypertrophy with chronic hypoxia in mice. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S182-S182
Mikiyasu Shirai, Mathew Jenkins, Takashi Sonobe, Yutaka Fujii, Hirotsugu Tsuchimochi, Misa Yoshimoto, Tadakatsu Inagaki, Naoto Yagi, James Pearson. Abnormal cross-bridge dynamics in the in situ beating rat heart in early diabetes. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S182-S182

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Professional career (1)：

Doctor of Science (The University of Electro-Communications)

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