Rchr
J-GLOBAL ID：201601003934344238
Update date: Oct. 07, 2024
Abe Yuichi
アベユウイチ | Abe Yuichi
Affiliation and department：
Job title：
Designated Associate Professor
Other affiliations (1)：
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Nagoya University
Institute for Glyco-core Research, Integrated Glycan-Big Data Center
Designated Associate Professor
Research field (2)：
Chemical biology
, Tumor diagnostics and therapeutics
Research keywords (5)：
Proteogenomics
, Antigen-Antibody Profiling
, PTM proteomics
, Glycan Antigen
, Omics-based Medicine
Research theme for competitive and other funds (7)：
- 2024 - 2027 翻訳後修飾/ゲノム変異依存的な抗原-抗体複合体プロテオーム手法の開発
- 2021 - 2025 細胞外基質による細胞機能制御機構の包括的理解とその応用基盤の研究
- 2020 - 2025 Reverse Trans-Omics Analysis for Comprehensive Bottom-up Understanding Toward Conquering Cancer Systems
- 2022 - 2024 ハイスループット自己抗原プロテオミクスによる膵癌特異的抗原の同定と早期診断マーカーパネルの構築
- 2020 - 2023 Establishment of precisoin medicine for malti-omics approaches using cancer tissue
- 2019 - 2022 Exploration of novel therapeutic targets for renal cancer by multi-omics analysis and development of treatment algorithm
- 2021 - 2022 転移性大腸癌においてプロテオームレベルの制御を受ける癌免疫逸脱機構の解析
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Papers (29)：
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Hirokazu Shoji, Hidekazu Hirano, Yosui Nojima, Daigo Gunji, Akina Shinkura, Satoshi Muraoka, Yuichi Abe, Ryohei Narumi, Chioko Nagao, Masahiko Aoki, et al. Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy and guides targeted cancer treatment. Cell Reports. 2024. 114774-114774
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Yusuke Okuda, Takaya Shimura, Yuichi Abe, Hiroyasu Iwasaki, Ruriko Nishigaki, Shigeki Fukusada, Naomi Sugimura, Mika Kitagawa, Tamaki Yamada, Ayumu Taguchi, et al. Urinary dipeptidase 1 and trefoil factor 1 are promising biomarkers for early diagnosis of colorectal cancer. Journal of Gastroenterology. 2024. 59. 7. 572-585
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Nanami Hasegawa, Mayue Hongo, Misaki Okada, Takahisa Kuga, Yuichi Abe, Jun Adachi, Takeshi Tomonaga, Naoto Yamaguchi, Yuji Nakayama. Phosphotyrosine proteomics in cells synchronized at monopolar cytokinesis reveals EphA2 as functioning in cytokinesis. Experimental Cell Research. 2023. 432. 1. 113783-113783
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Yosui Nojima, Masahiko Aoki, Suyong Re, Hidekazu Hirano, Yuichi Abe, Ryohei Narumi, Satoshi Muraoka, Hirokazu Shoji, Kazufumi Honda, Takeshi Tomonaga, et al. Integration of pharmacoproteomic and computational approaches reveals the cellular signal transduction pathways affected by apatinib in gastric cancer cell lines. Computational and Structural Biotechnology Journal. 2023
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Kentaro Kajiwara, Ping-Kuan Chen, Yuichi Abe, Satoru Okuda, Shunsuke Kon, Jun Adachi, Takeshi Tomonaga, Yasuyuki Fujita, Masato Okada. Src activation in lipid rafts confers epithelial cells with invasive potential to escape from apical extrusion during cell competition. Current biology : CB. 2022. 32. 16. 3460-3476
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MISC (3)：
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鬼谷 薫, 三浦 奈美, 杉浦 悠毅, 阿部 雄一, 渡部 幸央, 角屋 貴則, 森 泰昌, 吉本 世一, 足立 淳, 清位 孝夫, et al. プリンヌクレオチド生合成経路を介したITKによる舌扁平上皮癌の新たな治療戦略の可能性. 日本分子腫瘍マーカー研究会誌. 2022. 37. 32-33
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鬼谷 薫, 三浦 奈美, 杉浦 悠毅, 阿部 雄一, 渡部 幸央, 角屋 貴則, 森 泰昌, 吉本 世一, 足立 淳, 清位 孝夫, et al. プリンヌクレオチド生合成経路を介したITKによる舌扁平上皮癌の新たな治療戦略の可能性. 日本分子腫瘍マーカー研究会プログラム・講演抄録. 2021. 41回. 68-69
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Abe Y, Aly H.H, Imamura M, Wakita T, Shimotohno K, Chayama K, Hijikata M. Thromboxane A2 synthase plays a key role in production of infectious HCV particles. 19th International symposium on hepatitis C virus and related viruses. Venice, Italy, Oct 5-9, 2012. 2012
Patents (2)：
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抗原分子の単離方法
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尿中タンパクバイオマーカーによる非侵襲大腸癌診断
Lectures and oral presentations (6)：
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免疫グロブリン結合タンパク質の高深度プロテオーム解析と、新規がんバイオマーカー探索研究への応用
(日本プロテオーム学会2022 2022)
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Temporal omics profiling using a mouse model of nonalcoholic steatohepatitis-associated hepatocellular carcinoma.
(2021)
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がんプレシジョンメディスンの構築に向けた臨床プロテオミクス解析基盤の開発
(第18回日本質量分析学会中部談話会 2021)
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胃がん内視鏡検体の高感度リン酸化プロテオミクスに基づくキナーゼ活性プロファイリング
(2019)
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網羅的チロシンリン酸化プロテオミクス解析法の構築~クリニカルプロテオミクスへ向けた技術開発~
(第12回日本質量分析学会中部談話会 2019)
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Education (3)：
- 2010 - 2013 Kyoto University Graduate School of Biostudies, Division of Systemic Life Science
- 2008 - 2010 Kyoto University Graduate School of Biostudies, Division of Systemic Life Science
- 2003 - 2008 Kyoto University Faculty of Science
Professional career (1)：
Work history (5)：
- 2024/03 - 現在 Nagoya University Institute for Glyco-core Research, Integrated Glycan-Big Data Center Designated Associate Professor
- 2024/03 - 現在 Gifu University Institute for Glyco-core Research, Integrated Glyco-Molecular Science Center Designated Associate Professor
- 2019/01 - 2024/02 Aichi Cancer Center Research Institute Division of Molecular Diagnosis Senior Researcher
- 2014/03 - 2018/12 National Institute of Biomedical Innovation, Health, and Nutrition Proteome Research Project Postdoctoral Associate
- 2013/08 - 2014/02 Japan Society for the Promotion of Science Research Fellowship for Young Scientists
Awards (5)：
- 2023/10 - Oral presentation award at Annual meeting in Aichi Cancer Center Research Institute
- 2020/10 - 日本プロテオーム学会 日本プロテオーム学会奨励賞 癌生検検体を用いた患者個別リン酸化プロテオーム解析手法の開発
- 2016/09 - 日本プロテオーム学会トラベルアワード
- 2011/08 - Kyoto University Support for study and research abroad, and for English improvement
- 2010/04 - Honjo International Scholarship Foundation Scholarship for Japanese Domestic Students
Association Membership(s) (4)：
The Human Proteome Organization
, Japanese Proteomics Society
, THE JAPANESE CANCER ASSOCIATION
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
