Taguchi Kumiko

タグチクミコ | Taguchi Kumiko

Affiliation and department：

Research field (2)： Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (7)：大血管障害 , 糖尿病 , マイクロパーティクル , 細胞外小胞 , 分子薬理学 , 血管内皮機能不全 , GRK2

Research theme for competitive and other funds (4)：

2021 - 2024 糖尿病性血管内皮障害時におけるβアレスチンによる細胞内シグナル伝達活性化の有効性
2017 - 2020 GRK2 as a potential molecular targeting drug discovery for diabetic endothelial dysfunction
2015 - 2016 Molecular preventative mechanism of vascular endothelial dysfunction in diabetes under GRK2 control
2013 - 2014 Molecular pharmacological characterization of GRK2 control mechanism in endothelial dysfunction

Papers (107)：

Kumiko Taguchi, Hiroyuki Kondo, Takayuki Matsumoto, Tsuneo Kobayashi. Effect of esaxerenone on the onset of aortic endothelial dysfunction and circulating microparticles in type 1 diabetic male mice. Scientific Reports. 2024. 14. 1. 26266
Takayuki Matsumoto, Takayuki Nagano, Kumiko Taguchi, Tsuneo Kobayashi, Naoko Tanaka-Totoribe. Toll-like receptor 3 involvement in vascular function. European Journal of Pharmacology. 2024. 979. 176842-176842
Takayuki Matsumoto, Kumiko Taguchi, Tsuneo Kobayashi. Role of TRPV4 on vascular tone regulation in pathophysiological states. European Journal of Pharmacology. 2023. 959. 176104-176104
Takayuki Matsumoto, Tomoe Osada, Kumiko Taguchi, Tsuneo Kobayashi. Endothelial Dysfunction in Superior Mesenteric Arteries Isolated from Adenine-Induced Renal Failure in Model Rats. Biological and Pharmaceutical Bulletin. 2023. 46. 8. 1156-1160
Kumiko Taguchi, Kanami Okudaira, Takayuki Matsumoto, Tsuneo Kobayashi. Ginkgolide B caused the activation of the Akt/eNOS pathway through the antioxidant effect of SOD1 in the diabetic aorta. Pflügers Archiv - European Journal of Physiology. 2023. 475. 4. 453-463

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MISC (40)：

Kumiko Taguchi. Elucidation of;diabetogenic mechanisms of vascular endothelial dysfunction underlying release;signaling of circulating microparticles. 2023. 65. 63-70
田口久美子, 小林恒雄. 糖尿病時産生放出されるmicroparticlesによる血管内皮機能障害の発症機構. 日本病態生理学会雑誌. 2023. 32. 3. 14-22
The role of endothelin-1 on diabetic vasculopathy and beneficial effects of current therapeutic drugs for diabetes on the vascular endothelin-1 system. 2014. 56. 107-126
Hideaki Tagashira, Takayuki Matsumoto, Kumiko Taguchi, Tsuneo Kobayashi, Kohji Fukunaga. Sigma-1 receptor stimulation improves NO-mediated aortic relaxation in pressure overload-induced vascular injury. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 86P-86P
Takayuki Matsumoto, Shun Watanabe, Kumiko Taguchi, Tsuneo Kobayashi. Increased Up(4)A-induced contraction in type 2 diabetic renal artery due to activated COX/thromboxane receptor axis. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 196P-196P

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Patents (1)：

P2X4受容体拮抗剤

Professional career (1)：

博士(薬学) (星薬科大学)

Work history (5)：

2019 - 現在星薬科大学医薬品化学研究所機能形態学研究室講師
2013 - 2018 Hoshi University Hoshi University
2012 - 2013 University of Toyama
2009 - 2012 Hoshi University
2004 - 2009 日本ケミファ株式会社

Awards (3)：

2014 - 日本薬学会関東支部奨励賞
2014 - 日本平滑筋学会栗山煕賞
2012 - 日本循環薬理学会 Young Investigator`s Award

Association Membership(s) (5)：

JAPANESE JOURNAL FOR CIRCULATION RESEARCH , Japanese Association of Cardiovascular Pharmacology , THE PHARMACEUTICAL SOCIETY OF JAPAN , JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH , THE JAPANESE PHARMACOLOGICAL SOCIETY

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