Research theme for competitive and other funds (4):
2022 - 2025 リソソームCa2+恒常性維持を介したT細胞老化制御機構の解明
2019 - 2021 Rabによるオートファジーを介したアレルギー性気道炎症の慢性化機序の解明
2017 - 2018 核ラミナによるクロマチン構造変化を介したT細胞老化制御機構の解明
2015 - 2016 Menin によるエネル ギー代謝調節を介し た免疫老化制御機構 の解明
Papers (20):
Waichi Yamamoto, Taisuke Hamada, Junpei Suzuki, Yuko Matsuoka, Miyuki Omori-Miyake, Makoto Kuwahara, Akira Matsumoto, Shunsuke Nomura, Amane Konishi, Toshihiro Yorozuya, et al. Suppressive effect of the anesthetic propofol on the T cell function and T cell-dependent immune responses. Scientific reports. 2024. 14. 1. 19337-19337
Toshio Kakuda, Junpei Suzuki, Yuko Matsuoka, Tadahiko Kikugawa, Takashi Saika, Masakatsu Yamashita. Senescent CD8+ T cells acquire NK cell-like innate functions to promote antitumor immunity. Cancer science. 2023. 114. 7. 2810-2820
Haruna Noda, Junpei Suzuki, Yuko Matsuoka, Akira Matsumoto, Makoto Kuwahara, Yoshiaki Kamei, Yasutsugu Takada, Masakatsu Yamashita. The histone demethylase Utx controls CD8+ T-cell-dependent antitumor immunity via epigenetic regulation of the effector function. Cancer science. 2023
Amane Konishi, Junpei Suzuki, Makoto Kuwahara, Akira Matsumoto, Shunsuke Nomura, Tomoyoshi Soga, Toshihiro Yorozuya, Masakatsu Yamashita. Glucocorticoid imprints a low glucose metabolism onto CD8 T cells and induces the persistent suppression of the immune response. Biochemical and biophysical research communications. 2021. 588. 34-40