BABA YOSHIFUMI

2018 - 2021 Fusobacterium nucleatum Confers Chemoresistance by Modulating Autophagy in Esophageal Squamous Cell Carcinoma

2018 - 2020 Comprehensive analysis of gut microbiome and sarcopenia in gastrointestinal cancers

2017 - 2020 Comprehensive analysis of gut microbiome and epigenetic changes in esophageal cancer.

2017 - 2020 Investigation of CCN family for development and drug resistance of gastrointestinal cancers

2017 - 2020 Comprehensive analysis of cancer cachexia signaling pathway for identifying a new therapeutic strategy in colorectal cancer.

2018 - 2020 Analysis of microbiome and epigenetics for the development of novel biomarker in Gastrointestinal cancers

2017 - 2019 Comprehensive analysis of gut microbiome before and after gastroenterological surgery.

2016 - 2019 The identification of molecular markers associated with resistance for molecular targeted agents in GIST

2016 - 2018 Functional analyses and developments of new therapies targeting LSD1 in gastrointestinal cancers

2015 - 2018 Global genomic analysis of the stromal compartments of the esophagus toward the establishment of novel treatment for esophageal cancer.

2015 - 2018 Comprehensive analysis to elucidate the mechanism of cancer metabolism in esophageal squamous cell carcinoma

2015 - 2018 Development of the new treatment strategy targeting microRNA which controls histone de-methylase

2014 - 2017 The identification of novel microRNAs regulating cancer stem cell properties and the clinical application to therapeutic strategy in gastrointestinal cancer

2014 - 2017 TET family proteins and 5-hydroxymethylcytosine in gastrointestinal carcinoma.

2014 - 2017 Clarification of the microRNA pathway regulating resistance to Trastuzumab in gastric cancer

2014 - 2017 Comprehensive analysis of mutation in PI3K/AKT pathway genes in esophageal cancer.

2014 - 2017 Epigenome analysis of cancer metabolism for the development of new biomarkers in esophageal cancer.

2015 - 2016 消化管癌の新規バイオマーカー開発をめざしたDNA脱メチル化関連酵素の網羅的解析

2013 - 2016 Tumor-suppressive effects and mechanism of a novel PPAR gamma agonist in esophageal caner

2012 - 2016 Individualized treatment strategy for esophageal cancer based on the expression of microRNAs in preoperative biopsy specimens.

2013 - 2015 Changes in expression levels of ERCC1, DPD, and VEGFA mRNA after first-line chemotherapy of metastatic colorectal cancer

2012 - 2015 Comprehensive analysis of LINE-1 methylation level in gastric cancer.

2012 - 2015 The novel markers to predict the sensitivity to chemotherapy in ESCC and GC

2012 - 2014 Comprehensive analysis of IGF2 DMR0 methylation level in esophageal cancer

2011 - 2014 Comprehensive analysis of LINE-1 hypomethylation level aimed at the development of new treatments for esophageal cancer

2011 - 2013 Pseudogene affected gene expression via regulating microRNA in esopheal squamous cancer

2011 - 2013 Global analysis of genomic alterations associated with AKT and ERK pathway in esophageal squamous cell carcinoma

2011 - 2013 The significance of transcription-reverse transcription concerted reaction method for detecting circulating tumor cells in patients with colorectal cancer and for anticancer drug sensitivity marker.

2011 - 2013 p53 and autophagy in colorectal cancer : function mechanism and Therapeutic applications

2011 - 2012 Can mTOR become target of the molecular target therapy in esophagus squamous cell carcinoma?