Research keywords (3)：
viral hepatitis
, PKR
, Hepatocellular carcinoma
Research theme for competitive and other funds (3)：
2020 - 2023 The role of PKR in hepatocellular carcinoma associated with intracellular metabolism
2018 - 2020 The inhibitor of protein kinase R (PKR) suppresses tumor proliferation and angiogenesis in hepatocellular carcinoma in vitro and in vivo models
2016 - 2018 The study to clarify the tumor suppressive effect of PKR inhibitor in hepatocellular carcinoma using in vivo imaging
Papers (190)：
Yusuke Okujima, Takao Watanabe, Takeshi Ito, Yasumichi Inoue, Yutaka Kasai, Yusuke Imai, Yoshiko Nakamura, Mitsuhito Koizumi, Osamu Yoshida, Yoshio Tokumoto, et al. PKR associates with 4.1R to promote anchorage-independent growth of hepatocellular carcinoma and lead to poor prognosis. Scientific reports. 2024. 14. 1. 27768-27768
Akihito Shiomi, Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Takao Watanabe, Ayumi Kanamoto, Masumi Miyazaki, Hironobu Nakaguchi, Yoshio Tokumoto, et al. Combined effect of histological findings and diabetes mellitus on liver-related events in patients with metabolic dysfunction-associated steatotic liver disease. Hepatology research : the official journal of the Japan Society of Hepatology. 2024
Yu Hashimoto, Yoshio Tokumoto, Takao Watanabe, Yusuke Ogi, Hiroki Sugishita, Satoshi Akita, Kazuki Niida, Mirai Hayashi, Masaya Okada, Kana Shiraishi, et al. C16, a PKR inhibitor, suppresses cell proliferation by regulating the cell cycle via p21 in colorectal cancer. Scientific reports. 2024. 14. 1. 9029-9029
Ryo Yano, Masashi Hirooka, Yoshiko Nakamura, Yusuke Imai, Yohei Koizumi, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa. A case of hepatocellular carcinoma with pseudoaneurysm formation upon lenvatinib administration. Clinical journal of gastroenterology. 2024. 17. 2. 319-326
Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Masumi Miyazaki, Akihito Shiomi, Ayumi Kanamoto, Hironobu Nakaguchi, Yoshiko Nakamura, Yusuke Imai, et al. Glycemic Control Is Associated with Histological Findings of Nonalcoholic Fatty Liver Disease. Diabetes & metabolism journal. 2024
Masanori Abe, Osamu Yoshida, Takao Watanabe, Kotaro Sunago, Atsushi Yukimoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Yoichi Hiasa. VALIDITY AND RELIABILITY OF PBC-10 IN THE ASSESSMENT OF THE HEALTH-RELATED QOL IN JAPANESE PATIENTS WITH PBC. HEPATOLOGY. 2021. 74. 787A-787A
Yohei Koizumi, Masashi Hirooka, Kotaro Sunago, Atsushi Yukimoto, Takao Watanabe, Osamu Yoshida, Masanori Abe, Yoichi Hiasa. GERIATRIC ASSESSMENT OF ELDERLY PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA PREDICTS WORSENING OF ALBI SCORE WITH MOLECULAR TARGETED THERAPY. HEPATOLOGY. 2021. 74. 644A-644A
2009 - 2013 Ehime University Graduate School Medicine
Professional career (1)：
医学博士 (愛媛大学)
Work history (2)：
2015/07 - 現在 Ehime University Graduate School of Medicine Department of Gastroenterology and Metabology specially appointed lecturer
2015/01 - 2015/06 Ehime University Graduate School of Medicine Department of Gastroenterology and Metabology assistant professor
Committee career (4)：
2021/01 - 現在 日本消化器病学会 学会評議員
2016 - 現在 日本消化器内視鏡学会 四国支部評議員
2016 - 現在 日本肝臓学会 西部会評議員
2016 - 現在 日本消化器病学会 四国支部評議員
Awards (4)：
2018 - JDDW 2018 KOBE 若手奨励賞
2016 - 第7回愛媛医学会奨励賞
2014 - 第13回 MSD Award (日本肝臓学会冠Award)
2012 - 日本消化器内視鏡学会四国支部学術奨励賞
Association Membership(s) (5)：
THE JAPANESE CANCER ASSOCIATION
, JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, JAPANESE SOCIETY OF GASTROENTEROLOGY
, The Japan Society of Hepatology
