MURAKAMI Gen

ムラカミゲン | MURAKAMI Gen

Affiliation and department：
Job title： Lecturer

Research field (1)： Neuroscience - general

Research theme for competitive and other funds (7)：

2020 - 2023 Analysis of neural mechanisms for neurodevelopmental disorders focusing on MHC expressed in dopaminergic neurons
2017 - 2021 The effect of maternal immune activation on drug addiction
2015 - 2019 Involvement of immune molecule MHC expressed in the brain in attention deficit/hyperactivity disorder
2015 - 2018 the effect of virus infection in the brain on cocaine addiction
2013 - 2016 Multimodal GABA systems responding to environmental stress

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Papers (39)：

Murakami G. 主要組織適合遺伝子複合体クラスI(MHCI)の機能欠損によるドーパミン系異常と精神疾患様行動. 埼玉医科大学雑誌. 2022. 48. 2. 96-97
Meng HR, Suenaga T, Edamura M, Fukuda A, Ishida Y, Nakahara D, Murakami G. Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression. Brain, Behavior, and Immunity. 2021. 97. 22-31
Gen Murakami, Mitsuhiro Edamura, Tomonori Furukawa, Hideya Kawasaki, Isao Kosugi, Atsuo Fukuda, Toshihide Iwashita, Daiichiro Nakahara. MHC class i in dopaminergic neurons suppresses relapse to reward seeking. Science Advances. 2018. 4. 3. eaap7388
G. Murakami, Y. Hojo, A. Kato, Y. Komatsuzaki, S. Horie, M. Soma, J. Kim, S. Kawato. Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid. Journal of Neuroendocrinology. 2018. 30. 2. e12561
Gen Murakami. Distinct Effects of Estrogen on Mouse Maternal Behavior: The Contribution of Estrogen Synthesis in the Brain. PLOS ONE. 2016. 11. 3. e0150728

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MISC (13)：

Murakami G. MHCI suppresses relapse. Science. 2018. 359. 1227-1227
Yasushi Hojo, Shimpei Higo, Hideo Mukai, Gen Murakami, Takeshi Yamazaki, Nobuhiro Harada, Seijiro Honma, Tetsuya Kimoto, Suguru Kawato. NEUROSTEROID SYNTHESIS AND SYNAPTOCRINOLOGY IN THE HIPPOCAMPAL SYNAPSES. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009. 59. 293-293
Gen Murakami, Rei Sato, Tomokazu Tsurugizawa, Yusuke Hatanaka, Yoshimasa Komatsuzaki, Yasushi Hojo, Hideo Mukai, Tetsuya Kimoto, Suguru Kawato. Effect of estrogen on spine regulation in hippocampus. NEUROSCIENCE RESEARCH. 2008. 61. S108-S108
Yasushi Hojo, Shimpei Higo, Hideo Mukai, Gen Murakami, Shiro Kominami, Nobuhiro Harada, Honma Seijiro, Tetsuya Kimoto, Suguru Kawato. Neurosteroid synthesis and synaptocrinology in the hippocampal synapses. NEUROSCIENCE RESEARCH. 2008. 61. S108-S108
Tetsuya Kimoto, Shimpei Higo, Hirotaka Ishii, Murakami Gen, Suguru Kawato. Expression analysis of neurosteroid receptors and steroidogenic enzymes in the rat hippocampus. NEUROSCIENCE RESEARCH. 2008. 61. S109-S109

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Books (3)：

Rapid effects of estradiol on dendritic spines and synaptic plasticity in the male and female hippocampus
Oxford 2020
Co-Immunoprecipitation methods to identify associated proteins with estrogen receptor α at postsynaptic density in brain tissue Neuro Methods
Springer Nature 2018
Local Production of Estrogen and its Rapid Modularory Action on Synaptic Plasticity
Springer 2008

Lectures and oral presentations (5)：

主要組織適合遺伝子複合体クラスI(MHCI)の機能欠損によるドーパミン系異常と精神疾患様行動
(オール埼玉医大研究の日特別講演 2021)
Comprehensive analysis of gene expression in a maternal immune activation mouse model of developmental disorders
(日本神経科学会 2020)
薬物依存の新たなメカニズム-ドーパミン神経細胞に発現する免疫分子MHCクラスIの関与
(アルコール薬物依存関連学会合同学術総会 2015)
Persistent reduction of MHC-I in dopamine neurons underlies enduring potentiation of its synaptic inputs in cocaine-seeking behavior
(Society for neuroscience 2015)
Involvement of Immune Protein MHC class I in The Development of Cocaine Self-Administration
(Society for neuroscience 2014)

Committee career (3)：

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