Rchr
J-GLOBAL ID:201601007261255179
Update date: Sep. 13, 2024
TOMOMASA YOKOMIZO
TOMOMASA YOKOMIZO
Affiliation and department:
Research field (2):
Developmental biology
, Hematology and oncology
Research theme for competitive and other funds (8):
- 2023 - 2026 The physiological and evolutionary significance of the limited site and timing of hematopoietic stem cell development
- 2023 - 2025 Development of methods for inducing hematopoietic stem cells
- 2022 - 2025 Elucidation of the molecular basis for age-dependent leukemogenesis towards a novel therapeutic strategy
- 2020 - 2023 細胞系譜追跡を用いた造血システム発生様式の解析
- 2017 - 2020 Elucidating the mechanism of hematopoietic stem cell development and maturation by using a novel reporter mouse
- 2015 - 2018 Development of a novel therapeutic method against acute megakaryoblastic leukemia by NOTCH agonists
- 2014 - 2017 Elucidating the mechanism of genome-wide transcriptional repression in hematopoietic stem cell development
- 2002 - 2004 造血発生における転写因子の役割に関する研究
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Papers (47):
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Saori Morino-Koga, Mariko Tsuruda, Xueyu Zhao, Shogo Oshiro, Tomomasa Yokomizo, Mariko Yamane, Shunsuke Tanigawa, Koichiro Miike, Shingo Usuki, Kei-ichiro Yasunaga, et al. Transition of signal requirement in hematopoietic stem cell development from hemogenic endothelial cells. Proceedings of the National Academy of Sciences. 2024. 121. 31
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Kelly Ooi Kee Ong, Michelle Meng Huang Mok, Akiko Niibori-Nambu, Linsen Du, Masatoshi Yanagida, Chelsia Qiuxia Wang, Avinash Govind Bahirvani, Desmond Wai Loon Chin, Cai Ping Koh, King Pan Ng, et al. Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia. Experimental hematology. 2024. 137. 104255-104255
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Wenjuan Ma, Yuichiro Arima, Terumasa Umemoto, Tomomasa Yokomizo, Yuqing Xu, Kenichi Miharada, Yosuke Tanaka, Toshio Suda. Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice. Experimental hematology. 2023
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Mohamed Gaber Abdallah, Vania Swee Imm Teoh, Bibek Dutta, Tomomasa Yokomizo, Motomi Osato. Childhood hematopoietic stem cells constitute the permissive window for RUNX1-ETO leukemogenesis. International journal of hematology. 2023
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Yuji Takihara, Takumi Higaki, Tomomasa Yokomizo, Terumasa Umemoto, Kazunori Ariyoshi, Michihiro Hashimoto, Maiko Sezaki, Hitoshi Takizawa, Toshihiro Inoue, Toshio Suda, et al. Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells. Communications Biology. 2022. 5. 1
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MISC (24):
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横溝 智雅, 森 誠一, 黒川 峰夫, 大里 元美, 小松 則夫. Hlfの発現は造血幹細胞の発生経路特異的に観察される(Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors). 日本癌学会総会記事. 2018. 77回. 1849-1849
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大里 元美, Ong Kelly Ooi Kee, Mok Michelle Meng Huang, 横溝 智雅, 松村 貴由, 須田 年生, 麻生 範雄, Koeffler Phillip, Tenen Daniel G., 清水 律子, et al. 急性巨核芽球性白血病に対するNOTCH活性化剤による新規治療(Notch activation impedes cell proliferation and survival in acute megakaryoblastic leukemia). 臨床血液. 2018. 59. 9. 1700-1700
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横溝 智雅, 渡邊 直紀, 梅本 晃正, 高久 智生, 須田 年生, 黒川 峰夫, 小松 則夫, 大里 元美. マウス胎生期における造血幹細胞の成熟はEvi-1/Hlf軸によって制御される(Evi-1/Hlf axis regulates HSC maturation in the mouse embryo). 臨床血液. 2018. 59. 9. 1571-1571
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Cai Ping Koh, Cherry Ee Lin Ng, Giselle Sek Suan Nah, Chelsia Qiuxia Wang, Vinay Tergaonkar, Takayoshi Matsumura, Tomomasa Yokomizo, Toshio Suda, Motomi Osato. Hematopoietic stem cell enhancer: A powerful tool in stem cell biology. Histology and Histopathology. 2015. 30. 6. 661-672
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飯塚 和秀, 横溝 智雅, 安田 肇, 小林 洋平, 高久 智生, 小松 則夫. マウス胎仔脳血管における造血幹細胞発生の可能性について. 順天堂醫事雑誌. 2013. 59. 6. 526-527
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Education (3):
- 1996 - 2001 Kyoto University
- 1994 - 1996 Kyoto University
- 1990 - 1994 Kyoto University Faculty of Engineering
Professional career (1):
Work history (1):
- 2022/04 - 現在 Tokyo Women's Medical University Department of Microscopic and Developmental Anatomy
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