Shiba Norio

シバノリオ | Shiba Norio

Research field (1)： Fetal medicine/Pediatrics

Research keywords (3)：小児 , AML , 遺伝子解析

Research theme for competitive and other funds (13)：

2020 - 2024 Establishment of easily high-precision risk stratification in pediatric acute myeloid leukemia
2020 - 2023 小児急性骨髄性白血病におけるEpigenetics 制御メカニズムの解明
2019 - 2022 Epigenomic analysis in refractory AML
2021 - 2022 小児急性骨髄性白血病におけるPRDM16-SKI融合遺伝子の意義の解明
2021 - 2022 再発難治小児急性骨髄性白血病に対する PRDM16 を標的とした新規核酸医薬の開発

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Papers (66)：

Genki Yamato, Yusuke Tsumura, Hideki Muramatsu, Akira Shimada, Takahiro Imaizumi, Hiroyuki Tsukagoshi, Taeko Kaburagi, Norio Shiba, Yoshiyuki Yamada, Takao Deguchi, et al. Cytokine profiling in 128 patients with transient abnormal myelopoiesis: a report from the JPLSG TAM-10 trial. Blood advances. 2024
Wataru Nakamura, Makoto Hirata, Satoyo Oda, Kenichi Chiba, Ai Okada, Raúl Nicolás Mateos, Masahiro Sugawa, Naoko Iida, Mineko Ushiama, Noriko Tanabe, et al. Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes. NPJ genomic medicine. 2024. 9. 1. 11-11
Yu Tao, Li Wei, Norio Shiba, Daisuke Tomizawa, Yasuhide Hayashi, Seishi Ogawa, Li Chen, Hua You. Development and validation of a promising 5-gene prognostic model for pediatric acute myeloid leukemia. Molecular biomedicine. 2024. 5. 1. 1-1
Takahiro Aoki, Norio Shiba, Shinichi Tsujimoto, Genki Yamato, Yusuke Hara, Shota Kato, Kenichi Yoshida, Seishi Ogawa, Yasuhide Hayashi, Shotaro Iwamoto, et al. High IL2RA/CD25 expression is a prognostic stem cell biomarker for pediatric acute myeloid leukemia without a core-binding factor. Pediatric blood & cancer. 2023. e30803
辻本信一, 加登翔太, 岩本彰太郎, 平松英文, 奥野友介, 神鳥達哉, 大木健太郎, 出口隆生, 清河信敬, 加藤元博, et al. KIT変異・FCM-MRDはRUNX1::RUNX1T1RUNX1陽性小児AMLにおける予後予測因子である. 日本血液学会学術集会. 2023. 85回. 142-142

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MISC (37)：

Tomoyasu Jo, Tomoko Henzan, Daisuke Tomizawa, Satoru Yoshihara, Kaoru Kahata, Minami Yamada-Fujiwara, Yoshiki Okuyama, Norio Shiba, Keiko Fujii, Yoshihiro Umezawa, et al. [Manufacturing results of tisagenlecleucel for acute lymphoblastic leukemia: a survey by the CAR-T cell therapy taskforce of the Japan Society of Transfusion Medicine and Cell Therapy]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2023. 64. 5. 331-337
Genki Yamato, Tomoko Kawai, Norio Shiba, Yusuke Hara, Kentaro Ohki, Taeko Kaburagi, Etsuko Ishikita, Hirohide Kawasaki, Kenichi Yoshida, Yuichi Shiraishi, et al. Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study. BLOOD. 2022. 140. 9134-9135
中村航, 須川正啓, Mateos Raul N., 飯田直子, 千葉健一, 平田真, 辻本信一, 柴徳生, 白石友一. Adaptive samplingを用いたロングリードシークエンス解析パイプラインの構築(An attempt to build a long-read sequencing pipeline using adaptive sampling.). 日本癌学会総会記事. 2022. 81回. P-3114
吉川奈央子, 西村謙一, 神山裕二, 大砂光正, 林邉廉, 村瀬絢子, 服部成良, 江中牧子, 辻本信一, 竹内正宜, et al. 自己免疫性溶血性貧血,血小板減少を合併したランゲルハンス細胞組織球症の早期乳児例. 日本小児科学会雑誌. 2022. 126. 2. 331-331
吉富誠弘, 田野島玲大, 秋山典子, 飯塚敦広, 林弘明, 辻本信一, 竹内正宣, 柴徳生, 伊藤秀一. 小児・Adolescent and Young Adult(AYA)世代がん患者長期フォローアップへの取り組み. 神奈川医学会雑誌. 2022. 49. 1. 51-51

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Books (1)：

小児内科2017年49巻増刊号小児臨床検査のポイント2017
東京医学社 2017

Lectures and oral presentations (207)：

Establishment of a high-risk AML cell line YCU-AML2 harboring KMT2A-MLLT3 and MECOM overexpression.
(2022)
Skin prick test can be useful to determine L-asparaginase continuation after skin reaction.
(2022)
Clinical outcome of CD25 high pediatric acute myeloid leukemia.
(2022)
Current status of treatment-induced adrenal insufficiency in pediatric leukemia.
(2022)
The comprehensive genome and transcriptome analysis of pediatric minimally differentiated acute myeloid leukemia and acute undifferentiated leukemia.
(2022)

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Professional career (1)：

博士(医学) (群馬大学)

Work history (1)：

2022/04 - 現在 Yokohama City University

Awards (3)：

2020/11 - Japanese Society of Pediatric Hematology / Oncology academic Award Japanese Society of Pediatric Hematology / Oncology Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia.
2017/11 - Academic award High PRDM16 expression identifies a prognostic subgroup of pediatric AML
2013/10 - 日本血液学会 2014年日本血液学会研究奨励賞

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