Rchr
J-GLOBAL ID:201601008252108836
Update date: Oct. 07, 2024
Katsuda Takeshi
Katsuda Takeshi
Affiliation and department:
Job title:
Assistant Professor
Research field (2):
Applied molecular and cellular biology
, Biomedical engineering
Research theme for competitive and other funds (2):
- 2016 - 2018 Generation of hepatic progenitor cells from human hepatocytes using small molecules
- 2015 - 2015 小分子化合物による成体肝細胞のリプログラミング
Papers (48):
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Takeshi Katsuda, Jonathan H Sussman, Kenneth S Zaret, Ben Z Stanger. The yin and yang of pioneer transcription factors: Dual roles in repression and activation. BioEssays : news and reviews in molecular, cellular and developmental biology. 2024. e2400138
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Jonathan H Sussman, Nathalia Kim, Samantha B Kemp, Daniel Traum, Takeshi Katsuda, Benjamin M Kahn, Jason Xu, Il-Kyu Kim, Cody Eskandarian, Devora Delman, et al. Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer. Cancer research. 2024. 84. 14. 2364-2376
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Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, et al. Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.). 2024. 385. 6705. eadl6173
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Takeshi Katsuda, Jonathan H Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J Merrell, Hector Cure, Qinglan Li, et al. Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity. Nature communications. 2024. 15. 1. 1761-1761
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Il-Kyu Kim, Mark S Diamond, Salina Yuan, Samantha B Kemp, Benjamin M Kahn, Qinglan Li, Jeffrey H Lin, Jinyang Li, Robert J Norgard, Stacy K Thomas, et al. Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma. Nature communications. 2024. 15. 1. 1532-1532
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MISC (31):
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三橋 愛, 小坂 展慶, 勝田 毅, 山本 雄介, 山元 智史, 藤原 康弘, 落谷 孝広. 乳癌においてmiRNA-1285-5pは腫瘍抑制性に機能する(miR-1285-5p functions as a tumor suppressor in breast cancer progression). 日本癌学会総会記事. 2018. 77回. 429-429
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三橋 愛, 小坂 展慶, 勝田 毅, 山本 雄介, 山元 智史, 藤原 康弘, 落谷 孝広. 乳がんにおける新規癌抑制性microRNA-Xの機能. 日本乳癌学会総会プログラム抄録集. 2018. 26回. 583-583
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勝田 毅, 落谷 孝広. 奨励賞(基礎) 成熟肝細胞からの,高い再生能を有しかつ培養可能な肝前駆細胞へのリプログラミング-In vitro reprogramming of mature hepatocytes to culturable liver progenitor cells and their potential application to regenerative medicine-2017年度日本再生医療学会. 再生医療 = Regenerative medicine : 日本再生医療学会雑誌. 2018. 17. 1. 78-84
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上野惟, 太田滋之, 倉田隼人, 野中秀紀, 石井強, 勝田毅, 落谷孝広, 河村大輔, 石川俊平. 肝障害モデルマウスを用いたヒト脂肪組織由来間葉系幹細胞の生体内微小環境下における性状解析. 日本再生医療学会総会(Web). 2018. 17th
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益田郁子, 倉田隼人, 倉田隼人, 倉田隼人, 石井強, 玉井里枝, 勝田毅, 河村大輔, 石川俊平, 落谷孝広. エクソソームに着目した間葉系幹細胞の品質管理の実用化に向けた検討. 日本再生医療学会総会(Web). 2018. 17th
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Lectures and oral presentations (10):
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肝細胞可塑性のエピジェネティクス機構
(千里ライフサイエンス,第66回新適塾「未来創発への誘い」 2024)
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Chemically induced liver progenitors as a novel cell source for liver regenerative medicine
(BDMC2024 2024)
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肝臓の不思議に迫る
(Microsoft Project Users Forum (MPUF),研究開発プロフェッショナルの流儀 2022)
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僕,肝臓を作れます
(Science-OME 2020)
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ヒト成熟肝細胞由来肝前駆細胞(CLiP)の開発と再生医療への応用可能性
(第18回日本再生医療学会SY-29-1)
more...
Work history (6):
Awards (9):
- 2024 - 第31回肝細胞研究会 最優秀演題賞 パイオニアファクターSOX4による肝細胞の胆管リプログラミング開始機構
- 2022 - FASEB Research Conference registration reimbursement award Hepatobiliary plasticity in vivo is mediated by Sox4 pioneer factor activity
- 2022 - P30 Digestive Disease Symposium, Poster Award The epigenetic basis of hepatobiliary plasticity following liver injury
- 2020 - The Regeneron Prize for Creative Innovation by a Postdoctoral Fellow Understanding Cell Competition in Mammalian Organ Size Control and Cancer
- 2017 - 日本再生医療学会 奨励賞(基礎部門) 成熟肝細胞から再生能を有する肝前駆細胞へのリプログラミング
- 2017 - 国立がん研究センター研究所 所長賞 In vitro generation of liver progenitor cells by chemical reprogramming and its application to cancer research
- 2015 - 三国立センター合同リトリート ポスター賞 Small molecule-mediated fate conversion of terminally committed hepatocytes to bipotential cells
- 2013 - ISEV Young Investigator Award (Poster) Potential roles of osteosarcoma-derived exosomes in pre-metastatic niche formation in the lung
- 2011 - 日本生化学会 JB論文賞 Transplantation of a fetal liver cell-loaded hyaluronic acid sponge onto the mesentery recovers a Wilson’s disease model rat
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