Ohsawa Kosuke

オオサワコウスケ | Ohsawa Kosuke

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (4)：ペプチド化学 , 生物有機化学 , 天然物合成 , organic synthesis

Research theme for competitive and other funds (3)：

Papers (18)：

Kota Sato, Yuto Sasaki, Michiko Ohno-Oishi, Kuniyuki Kano, Junken Aoki, Kosuke Ohsawa, Takayuki Doi, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Chihiro Kawano, et al. New Dihydropyridine Derivative Attenuates NF-κB Activation via Suppression of Calcium Influx in a Mouse BV-2 Microglial Cell Line. The Tohoku Journal of Experimental Medicine. 2024. 263. 151-160
Mazin A. S. Abdelwahid, Kosuke Ohsawa, Akiharu Uwamizu, Kuniyuki Kano, Junken Aoki, Takayuki Doi. Synthesis and Biological Evaluation of Lysophosphatidic Acid Analogues Using Conformational Restriction and Bioisosteric Replacement Strategies. ACS Omega. 2023. 8. 51. 49278-49288
Takayuki Doi, Kosuke Ohsawa, Yuichi Masuda. Cyclic Tetrapeptide Natural Product Asperterrestide A: Total Synthesis and Structural Revision. Journal of Synthetic Organic Chemistry, Japan. 2023. 81. 6. 554-561
Masaya Kumashiro, Kosuke Ohsawa, Takayuki Doi. Photocatalyzed Oxidative Decarboxylation Forming Aminovinylcysteine Containing Peptides. Catalysts. 2022. 12. 12. 1615-1615
Kosuke Ohsawa, Sakiko Fukaya, Takayuki Doi. Total Synthesis and Structural Determination of Cyclodepsipeptide Decatransin. Organic Letters. 2022. 24. 30. 5552-5556

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MISC (7)：

Kumashiro M, Ohsawa K, Doi T. Development of S-[2-aminovinyl]-3-methylcysteine construction using photoreaction. PEPTIDE SCIENCE 2023. 2024. 60. 25-26
大澤宏祐, 土井隆行. 環状デプシペプチド天然物の全合成および構造決定. 月刊「細胞」8月号. 2023. 55. 9. 37-40
Kosuke Ohsawa. Stereo-divergent Synthesis of Nonproteinogenic Amino Acids and Synthetic Study for Biologically Active Cyclopeptides Kosuke. 2023. 143. 7. 551-557
Kosuke Ohsawa, Sakiko Fukaya, Takayuki Doi. Total Synthesis and Structural Determination of Cyclodepsipeptide Decatransin. PEPTIDE SCIENCE 2022. 2023. 59. 105-106
Kosuke Ohsawa. Atom-economic Amidation and Esterification Mediated by Heteroatom-substituted Terminal Alkynes. Journal of Synthetic Organic Chemistry, Japan. 2021. 79. 8. 790-791

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Books (1)：

Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer
2015 ISBN:9784431554479

Lectures and oral presentations (116)：

SYNTHETIC PLAN OF N-ACETYL-N-HYDROXYORNITHINE CONTAININGCYCLIC PEPTIDE SIDEROPHORES: ASP2397 AS AN EXAMPLE
(第61回ペプチド討論会 2024)
分枝ペプチド抗生物質スタロバシンIの合成研究
(第50回反応と合成の進歩シンポジウム 2024)
チオアミド含有ペプチドDeoxyneothioviridamideの合成研究
(第66回天然有機化合物討論会 2024)
JBIR-141オキサゾール類縁体の合成研究
(第124回有機合成シンポジウム 2024)
分枝ペプチド抗生物質スタロバシンIの合成研究
(日本薬学会第144年会 2024)

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Education (4)：

2011 - 2014 Tohoku University Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
2012 - 2012 PESTECH
2009 - 2011 Tohoku University Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
2005 - 2009 Tohoku University Faculty of Pharmaceutical Sciences

Professional career (1)：

Work history (5)：

Committee career (5)：

Awards (4)：

Association Membership(s) (4)：

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , 日本ペプチド学会

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