Rchr
J-GLOBAL ID:201601009446051190   Update date: Sep. 27, 2024

Sasai Hiroaki

ササイ ヒロアキ | Sasai Hiroaki
Affiliation and department:
Research field  (2): Pharmaceuticals - chemistry and drug development ,  Synthetic organic chemistry
Research keywords  (11): Circularly Polarized Luminescence ,  flow reaction ,  machine learning ,  organocatalyst ,  rare earth catalyst ,  palladium catalyst ,  vanadium catalyst ,  heterobimetallic catalyst ,  SPRIX ,  domino reaction ,  asymmetric catalyst
Research theme for competitive and other funds  (50):
  • 2021 - 2026 Implementation of machine-learning-assisted simultaneous multiparameter screening for flow/electrochemical domino reactions
  • 2020 - 2026 Creation of Innovative Molecular Transformation Methods Induced by Electricity, Light, and Magnetic Field
  • 2018 - 2022 Development of Cooperative Chemo- and Biocatalysts and their Application in the Practical Synthesis of Biologically Active Molecules
  • 2016 - 2019 Visualization of chemical yield and enantioselectivity in organic reaction
  • 2012 - 2018 Practical molecular transformation based on the catalytic asymmetric domino reaction
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Papers (247):
  • Runze Zhao, Ismiyarto, Da-Yang Zhou, Kaori Asano, Takayoshi Suzuki, Hiroaki Sasai, Takeyuki Suzuki. General Synthesis of meso-1,4-Dialdehydes and Their Application in Ir-Catalyzed Asymmetric Tishchenko Reactions. ACS Omega. 2024. 9. 16. 17945-17955
  • Masaru Kondo, Hettiarachchige Dona Piyumi Wathsala, Kazunori Ishikawa, Daisuke Yamashita, Takeshi Miyazaki, Yoji Ohno, Hiroaki Sasai, Takashi Washio, Shinobu Takizawa. Bayesian Optimization-Assisted Screening to Identify Improved Reaction Conditions for Spiro-Dithiolane Synthesis. Molecules. 2023. 28. 13. 5180-5180
  • Masaru Kondo, Kento Nakamura, Chandu G. Krishnan, Hiroaki Sasai, Shinobu Takizawa. Photoswitchable Chiral Organocatalysts: Photocontrol of Enantioselective Reactions. The Chemical Record. 2023
  • Mohamed S.H. Salem, Md Imrul Khalid, Hiroaki Sasai, Shinobu Takizawa. Two-pot synthesis of unsymmetrical hetero[7]helicenes with intriguing optical properties. Tetrahedron. 2023. 133
  • Mohamed S.H. Salem, Md Imrul Khalid, Makoto Sako, Keigo Higashida, Charlie Lacroix, Masaru Kondo, Ryo Takishima, Taisei Taniguchi, Masahiro Miura, Giang Vo-Thanh, et al. Electrochemical Synthesis of Hetero[7]helicenes Containing Pyrrole and Furan Rings via an Oxidative Heterocoupling and Dehydrative Cyclization Sequence. Advanced Synthesis and Catalysis. 2023. 365. 3. 373-380
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MISC (52):
  • SALEM Mohamed S. H., KHALID Md. Imrul, SABRI Ahmed, SASAI Hiroaki, TAKIZAWA Shinobu. Electrochemical Synthesis of Hetero[7]helicenes, Dehydrohetero[7]helicenes and Hetero[8]circulenes with Intriguing Optical Features. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
  • SALEM Mohamed S. H., KHALID Md. Imrul, SAKO Makoto, TAKIZAWA Shinobu, SASAI Hiroaki. Electrochemical Synthesis of Azaoxa[7]helicenes via Oxidative Hetero-coupling/Dehydrative Cyclization Sequence of Arenols. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • Kamble Ganesh T., Salem Mohamed S. H., Salem Mohamed S. H., Abe Tsukasa, Park Hanseok, Sako Makoto, Takizawa Shinobu, Sasai Hiroaki. Chiral Vanadium(V)-catalyzed Oxidative Coupling of 4-Hydroxycarbazoles. Chemistry Letters (Web). 2021. 50. 10
  • SALEM Mohamed S. H., KHALID Md. Imrul, SAKO Makoto, KONDO Masaru, TAKIZAWA Shinobu, SASAI Hiroaki. Sequential electrochemical synthesis of cyclic dehydrooxahelicenes. 複素環化学討論会講演要旨集. 2021. 50th
  • SALEM Mohamed S. H., TAKIZAWA Shinobu, SASAI Hiroaki. Development of Anionic Octahedral Salicylimine-based Cobalt(III) Catalysts for Enantioselective Reactions. 日本薬学会年会要旨集(Web). 2020. 140th
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Patents (1):
  • chiral spiro isoxazoline-isoxazole derivatives and their preparation and catalytic asymmetric reaction using their transition metal complexes
Books (10):
  • Sustainable catalysis : with non-endangered metals
    Royal Society of Chemistry 2015 ISBN:9781782626381
  • Domino reactions : concepts for efficient organic synthesis
    Wiley-VCH 2014 ISBN:9783527334322
  • Comprehensive Organic Synthesis vol. 7: The Wacker Oxidation and Related Reactions
    Elsevier 2014
  • Comprehensive Organic Synthesis vol. 2: The Henry (Nitroaldol) Reactions
    Elsevier 2014
  • Comprehensive Chirality vol. 6: C-C bond formation, (aza) Morita-Baylis-Hillman Reaction
    Elsevier 2012 ISBN:9780080982182
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Lectures and oral presentations  (34):
  • Photoswitchable phase transfer catalyst: Design and application to enantioselective synthesis
    (2022)
  • 酸化的ヘテロカップリング・脱水環化・脱水素環化反応による光学活性アザオキサデヒドロ[7]ヘリセン類のドミノ合成研究
    (日本薬学会 第142年会 2022)
  • Enantioselective synthesis of hetero[9]helicenes using a chiral dinuclear vanadium(V) catalyst
    (2022)
  • A chiral vanadium(V) complex-catalyzed enantioselective oxidative coupling of hydroxycarbazoles
    (2022)
  • 光応答型ブレンステッド酸不斉触媒の創製研究
    (日本化学会 第102春季年会 2022)
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Education (3):
  • 1982 - 1985 Keio University Graduate School of Engineering Department of Applied Chemistry
  • 1980 - 1982 Keio University Graduate School of Engineering Department of Applied Chemistry
  • 1975 - 1980 Keio University Faculty of Engineering Department of Applied Chemistry
Work history (7):
  • 1997/08 - 現在 Osaka University The Institute of Scientific and Industrial Research Professor
  • 1997/04 - 1997/08 The University of Tokyo Graduate School of Pharmaceutical Sciences Associate Professor
  • 1995/04 - 1997/03 The University of Tokyo Faculty of Pharmaceutical Sciences Associate Professor
  • 1992/11 - 1995/03 The University of Tokyo Faculty of Pharmaceutical Sciences lecturer
  • 1992/04 - 1992/10 The University of Tokyo Faculty of Pharmaceutical Sciences Assistant Professor
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Awards (10):
  • 2018/04 - The Ministry of Education, Culture, Sports, Science and Technology, Japan Commendation for Science and Technology
  • 2016/02 - The Society of Synthetic Organic Chemistry, Japan Synthetic Organic Chemistry Award, Japan
  • 2011/05 - Molecular Chirality Organization Molecular Chirality Award 2011
  • 2009/12 - Asian Core Program Committee Lectureship Award
  • 2006/04 - Ichimura Foundation for New Technology Ichimura Science Award
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Association Membership(s) (6):
The Japanese Society for Process Chemistry ,  KINKA Chemical Society Japan ,  American Chemical Society ,  The Pharmaceutical Society of Japan ,  The Society of Synthetic Organic Chemistry, Japan ,  Chemical Society of Japan
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