Research field (4):
Functional biochemistry
, Molecular biology
, Biomedical engineering
, Environmental effects of radiation
Research theme for competitive and other funds (11):
2021 - 2024 Effective utilization of blood donation components using the activation phenomenon of white blood cells by nanosecond pulsed electric fields
2019 - 2022 DNA鎖のねじれ解消に働く酵素Top2がDNA二重鎖切断修復に果たす役割
2016 - 2019 プラズマ電荷刺激の生成輸送制御による細胞応答誘導機構
2016 - 2017 人体に痛みとして感知されない超短パルス高電界を利用した無痛癌治療法の開発
2013 - 2017 Interaction between pulsed power and organism and its applications
2014 - 2017 ナノ秒電気パルスを利用した低侵襲な癌治療法の開発
2016 - ナノ秒電気パルス誘導性ストレス応答を利用した癌治療
2013 - 2016 Study for a new cancer therapy using novel stress response evoked in tumor cells by nanosecond electric pulses
2011 - 2013 Analysis of a novel regulatory mechanism for DNA double-strand break repair by non-homologous end-joining
2008 - 2010 Analysis of a novel signaling pathway that regulates DNA damage recognition mediated by XLF
2001 - 2001 DNA組換修復遺伝子群の遺伝子多型と乳癌易罹患性の関連
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Papers (28):
Keiko Morotomi-Yano, Ken-ichi Yano. Aclarubicin reduces the nuclear mobility of human DNA topoisomerase IIβ. International Journal of Molecular Sciences. 2024. 25. 19. 10681
Airi Nakayama, Siwei Liu, Ken-ichi Yano, Tomoki Nakajima, Takehiko Sato. Cellular response to plasma-generated electrical and chemical stimulation of equal electricity. Journal of Physics D: Applied Physics. 2024. 57. 41. 415202
Keiko Morotomi-Yano, Shinya Hayami, Ken-ichi Yano. Adhesion states greatly affect cellular susceptibility to graphene xxide: therapeutic implications for cancer metastasis. International Journal of Molecular Sciences. 2024. 25. 3. 1927
Hayato Tada, Satoshi Uehara, Chia-Hsing Chang, Ken-ichi Yano, Takehiko Sato. Effect of nanosecond pulsed currents on directions of cell elongation and migration through time-lapse analysis. International Journal of Molecular Sciences. 2023. 24. 4. 3826-3826
Keiko Morotomi-Yano, Yukiko Hiromoto, Takumi Higaki, Ken-ichi Yano. Disease-associated H58Y mutation affects the nuclear dynamics of human DNA topoisomerase IIβ. Scientific Reports. 2022. 12. 1. 20627-20627