Rchr
J-GLOBAL ID：201601011418396615
Update date: Feb. 01, 2024
Masashi Kimura
キムラ マサシ | Masashi Kimura
Affiliation and department：
Gifu University Graduate School of Medicine
About Gifu University Graduate School of Medicine
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Detailed information
Other affiliations (1)：
医学系研究科
講師
Research field (4)：
Medical biochemistry
, Orthopedics
, Cell biology
, Pathobiochemistry
Research keywords (30)：
yeast two-hybrid
, histone H3
, colorectal cancer
, NEK
, Aurora(AIK)
, bladder cancer
, FRET
, ipl-related kinase)
, Aik (aurora
, breast cancer
, cell cycle
, dominant negative
, breast caencer
, 膀胱癌
, 大腸癌
, chromosome segregation
, NIMA
, 転写制御
, 大腸ガン
, 乳ガン
, がん
, 細胞死
, 染色体分配
, 中心体
, オーロラキナーゼ
, 細胞分裂
, cell division
, Aurora
, chromosome mapping
, centrosome
Research theme for competitive and other funds (7)：
2009 - 2013 オーロラキナーゼの細胞分裂における機能とがんにおける異常の解明
2009 - 2012 Elucidation of the function of Aurora kinases in mitosis and itsdysregulation in cancer
2005 - 2006 Aurora キナーゼによる細胞分裂制御と発がん機構の解析
2004 - 2005 レチノイドX受容体とRINGタンパク質の相互作用とそのユビキチン化・転写への効果
2001 - 2002 ステロイド受容体のユビキチン化の分子機構
2000 - 2001 ヒトAIKファミリータンパク質の細胞分裂における機能の解析
1998 - 1999 Aikの染色体分配における機能の解析とAikファミリーのcDNAクローニング
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Papers (19)：
Yoshiko Banno, Satoshi Nemoto, Masashi Murakani, Masashi Kimura, Yoshihito Ueno, Kenji Ohguchi, Akira Hara, Yukio Okano, Yukio Kitade, Minoru Onozuka, et al. Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway. JOURNAL OF NEUROCHEMISTRY. 2008. 104. 5. 1372-1386
Masashi Kimura, Yukio Okano. Human Misato regulates mitochondrial distribution and morphology. EXPERIMENTAL CELL RESEARCH. 2007. 313. 7. 1393-1404
K Sasai, H Katayama, DL Stenoien, S Fujii, R Honda, M Kimura, Y Okano, M Tatsuka, F Suzuki, EA Nigg, et al. Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. CELL MOTILITY AND THE CYTOSKELETON. 2004. 59. 4. 249-263
M Kimura, C Uchida, Y Takano, M Kitagawa, Y Okano. Cell cycle-dependent regulation of the human aurora B promoter. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004. 316. 3. 930-936
Okano Yukio(Dep, Mol Pathobiochen, Takahasi Yuzou(Dept Parasitology, Deguchi Takashi(Dep, Urology, Kimura Masashi(Dept, Mol Pathobiochen, Yoshioka Takashi(Dept, Mol pathobiochen. Expression of mitotic Aurora/lpllp-related kinases in renal sell carcinomas. 2003. 31. 382-386
ｍore...
MISC (53)：
M. Kimura, T. Yoshioka, M. Saio, Y. Banno, H. Nagaoka, Y. Okano. Mitotic catastrophe and cell death induced by depletion of centrosomal proteins. Cell Death and Disease. 2013. 4. 4
Katsuya Sato, Hiroaki Handa, Masashi Kimura, Yukio Okano, Hitoshi Nagaoka, Takahiro Nagase, Tsuyoshi Sugiyama, Yukio Kitade, Hiroshi Ueda. Identification of a Rho family specific guanine nucleotide exchange factor, FLJ00018, as a novel actin-binding protein. CELLULAR SIGNALLING. 2013. 25. 1. 41-49
A. Matsuhashi, T. Ohno, M. Kimura, A. Hara, M. Saio, A. Nagano, G. Kawai, M. Saitou, I. Takigami, K. Yamada, et al. Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and Aurora kinases. Current Cancer Drug Targets. 2012. 12. 6. 625-639
Takashi Yoshioka, Masashi Kimura, Masanao Saio, Seiichi Era, Yukio Okano. Plk1 is negatively regulated by RNF8. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011. 410. 1. 57-61
Naoki Mori, Chie Ishikawa, Masachika Senba, Masashi Kimura, Yukio Okano. Effects of AZD1152, a selective Aurora B kinase inhibitor, on Burkitt's and Hodgkin's lymphomas. BIOCHEMICAL PHARMACOLOGY. 2011. 81. 9. 1106-1115
ｍore...
Education (2)：
1989 - 1993 筑波大学博士課程生物科学研究科
1985 - 1989 筑波大学第二学群生物学類
Professional career (1)：
理学博士 (筑波大学)
Work history (2)：
2012 - Gifu University
1993/10/01 - Gifu University School of Medicine
Association Membership(s) (3)：
日本分子生物学会
, 日本生化学会
, 日本細胞生物学会
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