Okazaki Kei-ichi

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Research field (2)： Bio-, chemical, and soft-matter physics , Biophysics

Research keywords (4)：分子シミュレーション , 生体分子マシン , Computational Molecular Science , Theoretical Biophysics

Research theme for competitive and other funds (5)：

2022 - 2026 Mechanism of membrane-transforming biomolecular machines: Theoretical study of their oligomerization and conformational change
2018 - 2021 Theoretical prediction of mutations that speed up substrate transportation in transporter protein
2017 - 2019 Analysis of degradation mechanism of crystalline carbohydrates by high speed and precision single molecule observation
2009 - 2011 分子モーターの動作機構のマルチスケールな解析 : 全原子・粗視化シミュレーション
2007 - 2008 多谷エネルギー地形モデルによるタンパク質の構造変化機構のシミュレーション研究

Papers (34)：

Kazushi Okada, Takuma Kikutsuji, Kei-ichi Okazaki, Toshifumi Mori, Kang Kim, Nobuyuki Matubayasi. Unveiling interatomic distances influencing the reaction coordinates in alanine dipeptide isomerization: An explainable deep learning approach. The Journal of Chemical Physics. 2024
Tomoki Matsuda, Shinya Sakai, Kei-ichi Okazaki, Takeharu Nagai. Improvement of the Green-Red Förster Resonance Energy Transfer-Based Ca2+ Indicator by Using the Green Fluorescent Protein, Gamillus, with a Trans Chromophore as the Donor. ACS Sensors. 2024
Jun Ohnuki, Titouan Jaunet-Lahary, Atsuko Yamashita, Kei-ichi Okazaki. Accelerated Molecular Dynamics and AlphaFold Uncover a Missing Conformational State of Transporter Protein OxlT. The Journal of Physical Chemistry Letters. 2024
Jun Ohnuki, Titouan Jaunet-Lahary, Atsuko Yamashita, Kei-ichi Okazaki. Accelerated Molecular Dynamics and AlphaFold Uncover a Missing Conformational State of Transporter Protein OxlT. 2023
Maho Yagi-Utsumi, Haruko Miura, Christian Ganser, Hiroki Watanabe, Methanee Hiranyakorn, Tadashi Satoh, Takayuki Uchihashi, Koichi Kato, Kei-ichi Okazaki, Kazuhiro Aoki. Molecular Design of FRET Probes Based on Domain Rearrangement of Protein Disulfide Isomerase for Monitoring Intracellular Redox Status. International Journal of Molecular Sciences. 2023. 24. 16. 12865-12865

ｍore...

MISC (21)：

Kei-ichi Okazaki, Mitsuhiro Sugawa, Gerhard Hummer. Conformational Transition from Catalytic Dwell to ATP-Binding Dwell in F-1-ATPase. BIOPHYSICAL JOURNAL. 2017. 112. 3. 278A-278A
Kei-ichi Okazaki, Gerhard Hummer. Multiscale Analysis of Functional Motions in F1-ATPase: From Pi Release to Elasticity and Friction of gamma-Subunit Rotation. BIOPHYSICAL JOURNAL. 2015. 108. 2. 209A-209A
Kei-ichi Okazaki, Gerhard Hummer. Phosphate release coupled to rotary motion of F-1-ATPase. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2014. 247
Kei-ichi Okazaki, Gerhard Hummer. Exploring an Intermediate State of F1-ATPase by Atomistic Molecular Dynamics Simulation. BIOPHYSICAL JOURNAL. 2013. 104. 2. 332A-332A
Okazaki Kei-ichi, Takada Shoji. 3P163 Structural comparison of F_1-ATPase : Coupling among enzyme structures, reaction sites, and rotations(Molecular motor,The 48th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2010. 50. 2. S173

ｍore...

Lectures and oral presentations (11)：

分子シミュレーションとAlphaFoldの統合によるタンパク質構造変化ダイナミクスの解明
(物性研究所スパコン共同利用・CCMS合同研究会「計算物質科学の現在と未来」 2024)
Conformational dynamics of transporter proteins revealed by molecular simulation and AlphaFold2
(2023)
Molecular Simulation of functional motions in biomolecular machines
(The 6th International Conference on Molecular Simulation 2023)
分子シミュレーションと反応速度論・マルコフモデル
(第17回分子シミュレーションスクール-基礎から応用まで- 2023)
Accelerated Molecular Dynamics and AlphaFold Discover a Conformational State of Transporter Protein OxlT
(9th Annual CCPBioSim Conference: Biomolecular Simulations for a Better World 2023)

ｍore...

Education (3)：

Professional career (1)：

Work history (7)：

Show all

Awards (1)：

Association Membership(s) (1)：

日本生物物理学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page