Research theme for competitive and other funds (1)：
2019 - 2021 Drug repositioningによるアルファシヌクレイン凝集抑制薬の探索
Papers (15)：
Paras S. Minhas, Jeffrey R. Jones, Amira Latif-Hernandez, Yuki Sugiura, Aarooran S. Durairaj, Qian Wang, Siddhita D. Mhatre, Takeshi Uenaka, Joshua Crapser, Travis Conley, et al. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies. Science. 2024
Diane L Haakonsen, Michael Heider, Andrew J Ingersoll, Kayla Vodehnal, Samuel R Witus, Takeshi Uenaka, Marius Wernig, Michael Rapé. Stress response silencing by an E3 ligase mutated in neurodegeneration. Nature. 2024. 626. 8000. 874-880
Kelsie Eichel, Takeshi Uenaka, Vivek Belapurkar, Rui Lu, Shouqiang Cheng, Joseph S Pak, Caitlin A Taylor, Thomas C Südhof, Robert Malenka, Marius Wernig, et al. Endocytosis in the axon initial segment maintains neuronal polarity. Nature. 2022. 609. 7925. 128-135
Takeshi Uenaka, Wataru Satake, Pei-Chieng Cha, Hideki Hayakawa, Kousuke Baba, Shiying Jiang, Kazuhiro Kobayashi, Motoi Kanagawa, Yukinori Okada, Hideki Mochizuki, et al. In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease. Human molecular genetics. 2018. 27. 22. 3974-3985
T. Uenaka, W. Satake, C. P. Chieng, Y. Okada, T. Toda. In silico drug discovery for Parkinson's disease by using genome-wide association study (GWAS) data. MOVEMENT DISORDERS. 2015. 30. S51-S51
