Fujii Tomoaki

フジイトモアキ | Fujii Tomoaki

Affiliation and department：

Research field (1)： Genomics

Research theme for competitive and other funds (11)：

2019 - 2023 Identification of lncRNAs that influence BRAF mutation signal dependency
2016 - 2020 Identification of genes regulating metastasis in cancer stroma of colorectal cancer.
2014 - 2018 Analysis of adipocyte accumulation mechanism through histone H4 methylation
2014 - 2017 Identification of biomarker for colorectal cancer metastasis to lung with CAGE analyses
2014 - 2017 ヒストンH4メチル化修飾を介したエピジェネティックな脂肪蓄積制御機構の解明

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Papers (18)：

Xuan Wen, Min Han, Masaki Hosoya, Rika Toshima, Mai Onishi, Tomoaki Fujii, Shigeo Yamaguchi, Shunsuke Kato. Identification of BRAF Inhibitor Resistance-associated lncRNAs Using Genome-scale CRISPR-Cas9 Transcriptional Activation Screening. Anticancer research. 2024. 44. 6. 2349-2358
Min Han, Shigeo Yamaguchi, Mai Onishi, Tomoaki Fujii, Masaki Hosoya, Xuan Wen, Hidenori Kido, Shunsuke Kato. The MDM2 and CDKN2A Copy-number-variation Influence the TP53-signature-score in Wild-type TP53 Luminal Type Breast Cancer. Anticancer research. 2022. 42. 5. 2277-2288
Masataka Kojima, Kazunori Kajino, Shuji Momose, Nadila Wali, May Thinzar Hlaing, Bo Han, Liang Yue, Masaaki Abe, Tomoaki Fujii, Katsuhisa Ikeda, et al. Possible reversibility between epithelioid and sarcomatoid types of mesothelioma is independent of ERC/mesothelin expression. Respiratory research. 2020. 21. 1. 187-187
Kazuya Takakuwa, Kaoru Mogushi, Min Han, Tomoaki Fujii, Masaki Hosoya, Arina Yamanami, Tomomi Akita, Chikamasa Yamashita, Tetsu Hayashida, Shunsuke Kato, et al. A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma. Scientific reports. 2020. 10. 1. 6214-6214
Shigeo Yamaguchi, Tomoaki Fujii, Yuki Izumi, Yuki Fukumura, Min Han, Hideki Yamaguchi, Tomomi Akita, Chikamasa Yamashita, Shunsuke Kato, Takao Sekiya. Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Oncotarget. 2018. 9. 12. 10818-10827

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MISC (10)：

藤井智明, 真下知士. ゲノム編集技術CRISPR-Cas3とがん免疫療法への応用. 腫瘍内科. 2023. 31. 3. 366-370
藤井智明, 真下知士. 【遺伝子治療の最前線】遺伝子治療のためのゲノム編集技術. Medical Science Digest. 2022. 48. 13. 622-625
藤井智明, 吉見一人, 真下知士. ゲノム編集技術CRISPR-Cas3とそのCAR-T細胞療法への応用、. バイオエクス・プレス. 2020. 2020. 冬. 28-32
藤井智明, 吉見一人, 真下知士. ゲノム編集技術CRISPR-Cas3とその遺伝子治療および診断への応用. 実験医学増刊. 2020. 38. 17. 49(2841)
Yuki Izumi, Shigeo Yamaguchi, Tomoaki Fujii, Min Han, Yumi Nozaki, Chikamasa Yamashita, Syunsuke Kato. The functional assay of a variant unknown significance of APC gene derived from an adult pancreatoblastoma patient. ANNALS OF ONCOLOGY. 2017. 28. 82-82

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Lectures and oral presentations (28)：

白血病化おけるホメオボックスタンパク質による遺伝子発現機構の解析
(第8回築地キャンパス若手職員研究発表会 2024)
CRISPR-Cas3 technology for genome editing and its application to cancer immunotherapy
(2023)
藤井智明 , 吉見一人 , 竹下浩平 , 玉田耕治 , 真下知士
(2022)
Development of next generation CAR-T cell therapies with CRISPR-Cas3 technology
(2022)
Development of next generation CAR-T cell therapies with CRISPR-Cas3 technology
(2021)

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Education (3)：

2002 - 2006 The Graduate University for Advanced Studies School of Life Science Department of Genetics
2000 - 2002 Kitasato University Graduate School of Veterinary Medicine and Animal Sciences
- 2000 Kitasato University

Professional career (3)：

博士(理学) (総研大)
修士(農学) (北里大院)
学士(農学) (北里大)

Work history (7)：

2023/11 - 現在 National Cancer Center
2020/04 - 2023/10 東京大学医科学研究所先進動物ゲノム研究分野特任助教
2019/11 - 2020/03 東京大学医科学研究所先進動物ゲノム研究分野特任研究員
2015/04 - 2019/10 Sasaki Foundation
2013/04 - 2015/03 Juntendo University

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Association Membership(s) (6)：

アメリカ細胞生物学会 , THE GENETICS SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE CANCER ASSOCIATION , The Japanese Society for Genome Editing , Japan Society of Gene and Cell Therapy

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