Rchr
J-GLOBAL ID:201601014251658646
Update date: Mar. 08, 2024
Iwanami Jun
イワナミ ジュン | Iwanami Jun
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Affiliation and department:
Ehime University Department of Cell Biology and Molecular Medicine
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Research field (1):
Medical biochemistry
Research keywords (3):
認知機能
, 脳障害
, レニン・アンジオテンシン系
Research theme for competitive and other funds (8):
2021 - 2024 筋の健常性維持システムにおけるレニン・アンジオテンシン系の役割と筋疾患治療応用
2017 - 2020 Effects of transient cerebral ischemia on intracerebral amyloid beta metabolism and cognitive decline
2017 - 2020 Effect of protective arm of the renin-angiotensin system on ischemic brain damage
2016 - 2019 Exploration of new therapeutic approach to sarcopenic obesity focusing on ectopic fat deposition
2015 - 2017 Improvement of cognitive decline by cerebral AT2 receptor and HDAC2 inhibition
2013 - 2016 Elucidation of a preventive strategy against diabetic dementia induced by blood-brain barrier disruption
2013 - 2016 Systematic Approach for the Enhancement of Cognitive Function by the Activation of Angiotensin Type 2 receptor Associated Protein
2012 - 2014 Examination of the interaction of AT2 receptor and neurotransmitter in vascular dementia
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Papers (106):
Hui-Yu Bai, Li-Juan Min, Bao-Shuai Shan, Jun Iwanami, Harumi Kan-No, Motoi Kanagawa, Masaki Mogi, Masatsugu Horiuchi. Angiotensin II and Amyloid-β Synergistically Induce Brain Vascular Smooth Muscle Cell Senescence. American journal of hypertension. 2021. 34. 5. 552-562
Atsushi Yamaguchi, Tatsuya Jitsuishi, Takashi Hozumi, Jun Iwanami, Keiko Kitajo, Hiroo Yamaguchi, Yasutake Mori, Masaki Mogi, Setsu Sawai. Temporal expression profiling of DAMPs-related genes revealed the biphasic post-ischemic inflammation in the experimental stroke model. Molecular brain. 2020. 13. 1. 57-57
Li-Juan Min, Jun Iwanami, Masachika Shudou, Hui-Yu Bai, Bao-Shuai Shan, Akinori Higaki, Masaki Mogi, Masatsugu Horiuchi. Deterioration of cognitive function after transient cerebral ischemia with amyloid-β infusion-possible amelioration of cognitive function by AT2 receptor activation. Journal of neuroinflammation. 2020. 17. 1. 106-106
Narumoto Haruka, Iwanami Jun, Shan Bao-Shuai, Mogi Masaki, Narumoto Aoi, Min Li-Juan, Horiuchi Masatsugu. Effect of angiotensin II type 2 receptor on cerebral ischemic injury in mice with fetal growth restriction. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2019. 92. 2-P-041
Narumoto Aoi, Iwanami Jun, Narumoto Haruka, Kawakami Moe, Yamaguchi Risako, Kanno Harumi, Mogi Masaki, Min Li-Juan, Horiuchi Masatsugu. Hesperidin improves vascular remodeling in cuff-induced vascular injury mouse model. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2019. 92. 1-P-071
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MISC (135):
前畑葉月, 小林洋大, 岩波純, 茂木正樹, 堀内正嗣, 久原徹哉, 清水金忠. ビフィズス菌投与による脳血管性認知症モデルの認知機能低下に対する抑制作用. Dementia Japan. 2018. 32. 3. 440-440
莖田 昌敬, 大藏 隆文, 長尾 知明, 三好 賢一, 檜垣 彰典, 岩波 純, 茂木 正樹, 堀内 正嗣, 檜垣 實男. アンジオテンシンII2型(AT2)受容体刺激はLPSにより誘導される急性腎障害に対して保護的に働く. 日本腎臓学会誌. 2018. 60. 3. 460-460
茂木正樹, 川上萌, 岩波純, 堀内正嗣. 血管障害誘導性認知機能低下モデルにおける伊予柑ジュース飲用による認知機能低下の予防効果. 日本臨床栄養学会雑誌. 2018. 40. 1. 20-25-25
Toshifumi Yamauchi, Toshifumi Yamauchi, Masaki Mogi, Harumi Kan-No, Bao Shuai Shan, Akinori Higaki, Akinori Higaki, Li Juan Min, Takashi Higaki, Jun Iwanami, et al. Roles of angiotensin II type 2 receptor in mice with fetal growth restriction article. Hypertension Research. 2018. 41. 3. 157-164
閔 莉娟, 茂木 正樹, 単 宝帥, 岩波 純, 堀内 正嗣. AT2受容体によるPPARγ活性化を介した虚血性脳障害抑制作用. Anti-aging Science. 2017. 9. 2. 111-111
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Professional career (1):
医学博士 (愛媛大学)
Work history (1):
愛媛大学大学院医学系研究科 医化学・細胞生物学 准教授
Association Membership(s) (4):
日本脳血管・認知症学会
, 日本抗加齢医学会
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE JAPANESE SOCIETY OF HYPERTENSION
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