Rchr
J-GLOBAL ID：201601014567005911
Update date: Sep. 05, 2024
Hirasawa Yusuke
ヒラサワ ユウスケ | Hirasawa Yusuke
Affiliation and department：
Homepage URL (1)：
https://kaken.nii.ac.jp/d/r/90434183.ja.html
Research field (1)：
Environmental and pharmaceutical development resources
Research keywords (3)：
アルカロイド
, 薬学
, 天然物化学
Research theme for competitive and other funds (5)：
- 2022 - 2025 新規多量体インドールアルカロイドのキョウチクトウ科植物からの探索
- 2015 - 2016 Studies on the polymeric alkaloids and analysis of the mechanism of cell death
- 2013 - 2014 Studies on the alkaloids of Apocynaceae
- 2006 - 2007 ヒカゲノカズラ科植物を素材とする新機能性分子の探索と生合成経路の解明
- 2005 - 2007 Research for Antitumor Crude Drug from Malaysian Unutilized Plant Resorces
Papers (157)：
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Yusuke Hirasawa, Yusuke Kakizoe, Takahiro Tougan, Nahoko Uchiyama, Toshihiro Horii, Hiroshi Morita. Vincarostine A, a novel anti-malarial trimeric monoterpenoid indole alkaloid from Catharanthus roseus. Journal of Natural Medicines. 2024. 78. 3. 768-773
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Yuki Nakajima, Naohide Tsuboi, Kumiko Katori, Maigunuer Waili, Alfarius Eko Nugroho, Kazunori Takahashi, Hitomi Nishino, Yusuke Hirasawa, Yoko Kawasaki, Yukihiro Goda, et al. Oxomollugin, an oxidized substance in mollugin, inhibited LPS-induced NF-κB activation via the suppressive effects on essential activation factors of TLR4 signaling. Journal of Natural Medicines. 2024. 78. 3. 568-575
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Yusuke Hirasawa, Ayaka Kase, Akie Okamoto, Keigo Suzuki, Mizuki Hiroki, Toshio Kaneda, Nahoko Uchiyama, Hiroshi Morita. Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus. Journal of Natural Medicines. 2024. 78. 2. 382-392
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Alfarius Eko Nugroho, Tomoyuki Komuro, Takuya Kawaguchi, Yusuke Shindo, Chin Piow Wong, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, A Hamid A Hadi, et al. Ceramicines U-Z from Chisocheton ceramicus and structure-antimalarial activity relationship study. Journal of natural medicines. 2023
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Mizuki Hiroki, Aishanjiang Abulikemu, Chihiro Totsuka, Yusuke Hirasawa, Toshio Kaneda, Hiroshi Morita. Isovincathicine from Catharanthus roseus induces apoptosis in A549 cells. Journal of Natural Medicines. 2023
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MISC (106)：
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廣木美月, ABULIKEMU Aishanjiang, 戸塚千尋, 平澤祐介, 金田利夫, 森田博史. ニチニチソウから単離された二量体アルカロイドisovincathicineの細胞増殖阻害作用. 日本生薬学会年会講演要旨集. 2022. 68th
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出嶋堪哉, WONG Chin Piow, NUGROHO Alfarius Eko, 小泉瑤華, 金田利夫, 平澤祐介, 森田博史. Chisocheton ceramicusより単離されたceramicine Bの酸化ストレス応答. 日本生薬学会年会講演要旨集. 2022. 68th
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WAILI Maigunuer, 中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 高橋万紀, 川崎洋子, 合田幸広, 金田利夫, et al. OxomolluginのNF-κBシグナル阻害作用に関する検討. 日本生薬学会年会講演要旨集. 2021. 67th
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Alfarius Eko Nugroho, Yurika Ono, Eunji Jin, Yusuke Hirasawa, Toshio Kaneda, Abdul Rahman, Idha Kusumawati, Takahiro Tougan, Toshihiro Horii, Noor Cholies Zaini, et al. Bisindole alkaloids from Voacanga grandifolia leaves. Journal of Natural Medicines. 2021. 75. 2. 408-414
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中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 川崎洋子, 合田幸広, 金田利夫, 森田博史. Oxomollugin誘導体の抗炎症作用. 日本生薬学会年会講演要旨集. 2019. 66th
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Professional career (1)：
Work history (3)：
- 2015/07 - 現在 Hoshi University
- 2008/04 - 2015/06 Hoshi University
- 2006/04 - 2008/03 Hoshi University
Awards (5)：
- 2024 - 日本生薬学会 学術貢献賞 熱帯植物を利用した活性天然物の探索と構造研究
- 2020 - The Japanese Society of Pharmacognosy
- 2015 - 日本生薬学会 論文賞 Mumic acids A-E: new diterpenoids from mumiyo
- 2014 - 日本生薬学会 論文賞 Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma
- 2012 - 日本生薬学会 学術奨励賞 新規多環性骨格を有する機能性アルカロイドの探索研究
Association Membership(s) (2)：
THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF PHARMACOGNOSY
