2009 - 2010 Search for non-natural type bioactive compound produced by fungi.
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Papers (86)：
Ahmed H. El-Desoky, Keisuke Eguchi, Ippei Kagiyama, Yuki Hitora, Hikaru Kato, Yuji Ise, Fitje Losung, Remy E.P. Mangindaan, Sachiko Tsukamoto. Aaptocarbamates A-G, chlorinated terpene carbamates with antiosteoclastogenic activities from the marine sponge Aaptos sp. Phytochemistry. 2023. 216. 113872-113872
Ahmed H. El-Desoky, Toshifumi Asano, Yuka Maeyama, Hikaru Kato, Yuki Hitora, Eishu Goto, Shunsuke Kotani, Makoto Nakajima, Sachiko Tsukamoto. Arteperoxides A-C, tris-normonoterpene-sesquiterpene conjugates with peroxide-bridges from Artemisia judaica exhibiting antiosteoclastogenic activity. Phytochemistry. 2023. 206. 113548-113548
Ryoko Sasaki, Mary Ann Suico, Keisuke Chosa, Yuriko Teranishi, Takashi Sato, Asuka Kagami, Shunsuke Kotani, Hikaru Kato, Yuki Hitora, Sachiko Tsukamoto, et al. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors. Journal of Pharmacological Sciences. 2023. 151. 1. 54-62
Soichiro Nishimura, Yuki Hitora, Teppei Kawahara, Mika Tanabe, Eisuke Ogata, Hikaru Kato, Pattaravadee Srikoon, Takashi Watanabe, Sachiko Tsukamoto. Cell-based screening of extracts of natural sources to search for inhibitors of the ubiquitin-proteasome system and identification of proteasome inhibitors from the fungus Remotididymella sp. Bioorganic & Medicinal Chemistry Letters. 2022. 59. 128566-128566
Ahmed H H El-Desoky, Keisuke Eguchi, Naoki Kishimoto, Toshifumi Asano, Hikaru Kato, Yuki Hitora, Shunsuke Kotani, Teruya Nakamura, Soken Tsuchiya, Teppei Kawahara, et al. Isolation, Synthesis, and Structure-Activity Relationship Study on Daphnane and Tigliane Diterpenes as HIV Latency-Reversing Agents. Journal of medicinal chemistry. 2022. 65. 4. 3460-3472
西村宗一郎, 人羅勇気, 河原哲平, 加藤光, SRIKOON Pattaravadee, 渡邊高志, 塚本佐知子. Cell-based screening and identification of inhibitors of the ubiquitin-proteasome system from fungi. 日本薬学会年会要旨集(Web). 2021. 141st
Ahmed H.H. El-Desoky, Natsumi Inada, Yuka Maeyama, Hikaru Kato, Yuki Hitora, Momona Sebe, Mika Nagaki, Aika Kai, Keisuke Eguchi, Tomoaki Inazumi, et al. Taichunins E-T, Isopimarane Diterpenes and a 20- nor-Isopimarane, from Aspergillus taichungensis (IBT 19404): Structures and Inhibitory Effects on RANKL-Induced Formation of Multinuclear Osteoclasts. Journal of Natural Products. 2021
瀬治山藍, 人羅勇気, 加藤光, 河原哲平, MANGINDAAN Remy E. P., 塚本佐知子. Screening and identification of cell cycle inhibitors from natural products by fluorescent imaging of HeLa/Fucci2 cells. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
