Rchr
J-GLOBAL ID：201601015807005406   Update date: Jun. 18, 2024

TAKUSHI NOMURA

ノムラ タクシ | TAKUSHI NOMURA
Homepage URL  (1)： https://kumamoto-u-hrc-virop.wixsite.com/website
Research field  (2)： Immunology ,  Virology
Research theme for competitive and other funds  (13)：
  • 2024 - 2027 T細胞免疫老化によるSARS-CoV-2重症化機序の動物モデルを用いた解明
  • 2023 - 2026 HIVリザーバー解析に資する組織・細胞種特異的抗原発現マウスパネルの研究開発
  • 2022 - 2026 Impact of cross-reactive immunity to pre-existing infections on COVID-19 pathogenesis in East Africa
  • 2022 - 2025 Investigation for potential CTL epitopes spanning various coronavirues aiming for universal vaccine development
  • 2023 - 2024 T細胞の機能変化に着目したCOVID-19病態決定機序の解明
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Papers (29)：
  • Midori Nakamura-Hoshi, Hiroshi Ishii, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Nozomi Kuse, Midori Okazaki, Akira Ainai, Tadaki Suzuki, Hideki Hasegawa, et al. Prophylactic vaccination inducing anti-Env antibodies can result in protection against HTLV-1 challenge in macaques. Molecular therapy : the journal of the American Society of Gene Therapy. 2024
  • Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, et al. HTLV-1 Proliferation after CD8 + Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques. Microbiology Spectrum. 2023
  • Nana Afia Asante Ntim, Hiroshi Ishii, Moe Jomori, Hiroyuki Yamamoto, Tetsuro Matano, Takushi Nomura. Hierarchy of multiple viral CD8+ T-cell epitope mutations in sequential selection in simian immunodeficiency infection. Biochemical and biophysical research communications. 2022. 607. 124-130
  • Hiroshi Ishii, Kazutaka Terahara, Takushi Nomura, Midori Okazaki, Hiroyuki Yamamoto, Tsugumine Shu, Hiromi Sakawaki, Tomoyuki Miura, David I Watkins, Tetsuro Matano. Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8+ T cells but not CD4+ T cells. Molecular therapy : the journal of the American Society of Gene Therapy. 2022. 30. 5. 2048-2057
  • Hiroshi Ishii, Takushi Nomura, Hiroyuki Yamamoto, Masako Nishizawa, Trang Thi Thu Hau, Shigeyoshi Harada, Sayuri Seki, Midori Nakamura-Hoshi, Midori Okazaki, Sachie Daigen, et al. Neutralizing-antibody-independent SARS-CoV-2 control correlated with intranasal-vaccine-induced CD8+ T cell responses. Cell reports. Medicine. 2022. 3. 2. 100520-100520
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MISC (12)：
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Books (5)：
  • 「サルを用いたSARS-CoV-2感染症研究」
    ハムリー(実験動物情報交流会) 2021
  • Analysis of mechanism of long-term viral control in SIV infected rhesus macaque AIDS model
    2017
  • エイズ研究の最前線
    ハムリー 2017
  • HIV粘膜感染と宿主免疫
    羊土社 2016
  • エイズワクチン開発の論理
    日本ウイルス学会 2009
Lectures and oral presentations  (28)：
  • The development of a novel animal model for analyzing immune responses in tissues which contributes to eliminating the HIV reservoir.
    (2023)
  • Analysis of T-cell responses associated with age-dependent pathology in a SARS-CoV-2 infected mouse model.
    (2023)
  • サルエイズモデルにおける組織リザーバー解析
    (第34回日本エイズ学会学術集会 2020)
  • ワクチン誘導Gag241-249エピトープ特異的 CD8陽性T細胞の交差反応性が SIV感染に与える影響の解析
    (第33回日本エイズ学会学術集会 2019)
  • Contribution of vaccine-induced mutant epitope-crossreactive CD8+ T cells to stable control of SIVmac239 replication
    (The 37th Annual Symposium on Nonhuman Primate Models for AIDS 2019)
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Education (2)：
  • 2009 - 2013 The University of Tokyo
  • 2003 - 2009 Hokkaido University School of Veterinary Medicine Veterinary Medicine
Work history (4)：
  • 2022/02 - 現在 Joint Research Center for Human Retrovirus Infection, Kumamoto University Division of Virology and Pathology
  • 2018/05 - 2022/01 National Institute of Infectious Diseases AIDS Research Center Researcher
  • 2016/04 - 2018/05 Kumamoto University Center for AIDS Research Researcher
  • 2013/04 - 2016/03 National Institute of Infectious Diseases AIDS Research Center Researcher
Awards (5)：
  • 2023/11 - 第70回日本ウイルス学会学術集会 若手研究者優秀演題賞 SARS-CoV-2感染マウスモデルを用いた年齢依存的な病態に関連するT細胞動態の解析
  • 2019/11 - The 37th Annual Symposium on Nonhuman Primate Models for AIDS NHP2019 Travel Award Contribution of vaccine-induced mutant epitope-crossreactive CD8+ T cells to stable control of SIVmac239 replication
  • 2018/11 - 19th Kumamoto AIDS Seminar 19th Kumamoto AIDS Seminar Travel Award Gag epitope-specific CD8+ T cell responses in SIV controllers
  • 2017/11 - 日本エイズ学会 第17回日本エイズ学会ECC山口メモリアルエイズ研究奨励賞 サルエイズモデルを用いた長期ウイルス複製制御機序の解析
  • 2014/09 - The 32th Annual Symposium on Nonhuman Primate Models for AIDS NHP2014 Travel Award Lasting SIV control by multiple Gag, Vif, and Nef epitope-specific CD8+ T cells
Association Membership(s) (2)：
THE JAPANESE SOCIETY FOR AIDS RESEARCH ,  THE JAPANESE SOCIETY FOR VIROLOGY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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