Ikarashi Nobutomo

イカラシノブトモ | Ikarashi Nobutomo

Affiliation and department：
Job title：講師
Homepage URL (1)： https://kaken.nii.ac.jp/d/r/40409363.ja.html

Research field (2)： Pharmacology , Clinical pharmacy

Research keywords (8)：アクアポリン , 大腸 , 皮膚 , 腸内細菌 , 漢方薬 , 糖尿病 , 機能性食品 , 機能性化粧品

Research theme for competitive and other funds (18)：

2022 - 2025 食の変化が皮膚機能に与える影響;腸内細菌を基軸としたメカニズムの解析
2019 - 2022 腸内細菌-皮膚ネットワークの構築を目指して;皮膚機能分子の新規制御機構の解明
2020 - 2021 漢方医学の「水」理論を科学的に解き明かす;水輸送タンパク質「アクアポリン」に着目した解析
2016 - 2019 Novel therapeutic strategies for gastrointestinal diseases targeting membrane proteins responsive to gut microbiota
2016 - 2018 Effect of probiotics on diarrhea focusing on aquaporin in the colon

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Papers (316)：

Rinka Saito, Yui Shinozaki, Keito Tabata, Yui Nishinaka, Koki Yokoyama, Risako Kon, Hiroyasu Sakai, Tomoo Hosoe, Nobutomo Ikarashi. Tokishakuyakusan alleviates ultraviolet-induced skin pigmentation by decreasing the expression of melanogenesis-related enzymes. Journal of Ethnopharmacology. 2024. 332
Koki Yokoyama, Keito Tabata, Yui Shinozaki, Rinka Saito, Risako Kon, Hiroyasu Sakai, Tomoo Hosoe, Nobutomo Ikarashi. Effects of Tokishakuyakusan, Keishibukuryogan, and Kamishoyosan on the expression and activity of drug-metabolizing enzymes in the liver and small intestine. Pharmacological Research - Natural Products. 2024. 4. 100055-100055
Yu Miyauchi, Miho Kiyama, Shinki Soga, Hayato Nanri, Takayuki Ogiwara, Shiori Yonamine, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, et al. Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin. Biological & pharmaceutical bulletin. 2024. 47. 11. 1846-1850
Keito Tabata, Nobutomo Ikarashi, Yui Shinozaki, Ryotaro Yoshida, Risako Kon, Hiroyasu Sakai, Tomoo Hosoe, Junzo Kamei. Effect of the gut microbiota on the expression of genes that are important for maintaining skin function: Analysis using aged mice. The Journal of dermatology. 2023
Yui Shinozaki, Nobutomo Ikarashi, Keito Tabata, Ayuka Miyazawa, Risako Kon, Hiroyasu Sakai, Tomoo Hosoe. Expression analysis of genes important for maintaining skin function in a senescence-accelerated mouse prone model. Geriatrics & gerontology international. 2023

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MISC (294)：

齋藤凜佳, 篠崎優衣, 西中ゆい, 田端慶斗, 横山公紀, 今理紗子, 酒井寛泰, 細江智夫, 五十嵐信智. Elucidation of the mechanism by which tokishakuyakusan inhibits melanogenesis. 日本薬学会年会要旨集(Web). 2024. 144th
横山公紀, 田端慶斗, 篠崎優衣, 西中ゆい, 齋藤凜佳, 今理紗子, 酒井寛泰, 細江智夫, 五十嵐信智. Relationship between skin pigmentation caused by ultraviolet and aging. 日本薬学会年会要旨集(Web). 2024. 144th
木山美穂, 宮内優, 里史明, 今理紗子, 五十嵐信智, 千葉義彦, 細江智夫, 酒井寛泰. Effect of cisplatin on changing in the gene expression of collagen and elastin in dermal fibroblast. 日本薬学会年会要旨集(Web). 2024. 144th
南里駿仁, 曽我眞希, 木山美穂, 荻原隆行, 宮内優, 今理紗子, 五十嵐信智, 千葉義彦, 細江智夫, 酒井寛泰. Examination of endoplasmic reticulum stress response in skeletal muscles of mice treated with various anticancer drugs. 日本薬学会年会要旨集(Web). 2024. 144th
染谷柚杏, 千種佑也, 曽我眞希, 南里駿仁, 木山美穂, 荻原隆行, 宮内優, 千葉義彦, 今理紗子, 五十嵐信智, et al. Investigation of E3 ubiquitin ligase with altered gene expression during cisplatin-induced muscle atrophy. 日本薬学会年会要旨集(Web). 2024. 144th

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Lectures and oral presentations (1)：

浸透圧性下剤硫酸マグネシウムおよび大腸刺激性下剤ビサコジルの瀉下作用における大腸アクアポリン3の役割(Postdoctoral Award受賞講演,新時代を拓く医療薬学フロンティア)
(日本医療薬学会年会講演要旨集 2014)

Professional career (1)：

Work history (3)：

Awards (11)：

2023 - 優秀演題賞, 第11回日本くすりと糖尿病学会学術集会
2019 - Journal Natural Medicines Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon
2019 - 和漢医薬学会学術貢献賞
2014 - 第8回日本緩和医療薬学会年会優秀発表賞
2014 - 日本医療薬学会 Postdoctoral Award

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