Rchr
J-GLOBAL ID:201601016572155134   Update date: Jul. 16, 2024

Sugimoto Naoshi

Sugimoto Naoshi
Affiliation and department:
Research field  (6): Biomaterials ,  Biomedical engineering ,  Hematology and oncology ,  Hematology and oncology ,  Hematology and oncology ,  Hematology and oncology
Research keywords  (3): regenerative medicine ,  immunology ,  hematology
Research theme for competitive and other funds  (3):
  • 2021 - 2026 Elucidating the fundamental mechanism of platelet biogenesis and its medical application
  • 2021 - 2024 Elucidation of the NK cell immune escape mechanism using iPS cell-derived platelets and development of treatment
  • 2015 - 2019 The role of the nucleic acid sensor molecule DHX29 in hematopoietic cell immune responses and hematopoietic tumors
Papers (44):
  • Si Jing Chen, Kazuya Hashimoto, Kosuke Fujio, Karin Hayashi, Sudip Kumar Paul, Akinori Yuzuriha, Wei-Yin Qiu, Emiri Nakamura, Maria Alejandra Kanashiro, Mio Kabata, et al. A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility. Nature Communications. 2024. 15. 1
  • Charlotte Flahou, Tatsuya Morishima, Natsumi Higashi, Yoshikazu Hayashi, Huaigeng Xu, Bo Wang, Chaoqi Zhang, Atsushi Ninomiya, Wei-Yin Qiu, Akinori Yuzuriha, et al. Humanized mouse models with endogenously developed human natural killer cells for in vivo immunogenicity testing of HLA class I-edited iPSC-derived cells. Biochemical and biophysical research communications. 2023. 662. 76-83
  • 林 智也, 三島 優一, 中村 壮, 杉本 直志, 堀田 秋津, 正木 美香子, 田中 光信, 石井 博之, 立山 英美, 藤村 吉博, et al. ゲノム編集技術を用いたiPS細胞由来特異的HPA発現パネル細胞株の開発 HPA-3a抗体の特異的な検出. 日本輸血細胞治療学会誌. 2023. 69. 2. 283-283
  • Naoshi Sugimoto, Sou Nakamura, Shin Shimizu, Akiko Shigemasa, Junya Kanda, Nobuki Matsuyama, Mitsunobu Tanaka, Tomoya Hayashi, Akihiro Fuchizaki, Masayuki Nogawa, et al. Production and nonclinical evaluation of an autologous iPSC-derived platelet product for the iPLAT1 clinical trial. Blood advances. 2022. 6. 23. 6056-6069
  • Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Yasuyuki Arai, et al. iPLAT1: The first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study. Blood. 2022. 140. 22. 2398-2402
more...
MISC (46):
Books (1):
  • ハリソン内科学
    2017
Lectures and oral presentations  (24):
  • iPS細胞技術を用いた造血システムの再構成と治療への応用
    (第81回日本血液学会学術集会 2019)
  • iPS細胞を用いた血小板製剤の臨床応用の展望
    (第43回日本血液事業学会 2019)
  • Turbulence enables large scale production and clinical application of iPS cell-derived platelets
    (2019)
  • iPS血小板の開発と臨床応用
    (第18回先端医療フォーラム 2019)
  • iPS細胞由来血小板製剤の開発と将来
    (第50回日赤薬剤師会血液センター研究会 2019)
more...
Association Membership(s) (4):
THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  日本再生医療学会
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