Rchr
J-GLOBAL ID：201601016709516229   Update date: Sep. 26, 2024

Iwasaki Masayuki

Iwasaki Masayuki
Research field  (2)： Tumor biology ,  Pathobiochemistry
Research keywords  (6)： AML ,  Leukemia Stem Cells ,  MLL ,  MEIS1 ,  HOX ,  エピジェネティクス
Papers (45)：
  • Kelly Ooi Kee Ong, Michelle Meng Huang Mok, Akiko Niibori-Nambu, Linsen Du, Masatoshi Yanagida, Chelsia Qiuxia Wang, Avinash Govind Bahirvani, Desmond Wai Loon Chin, Cai Ping Koh, King Pan Ng, et al. Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia. Experimental Hematology. 2024. 137. 104255-104255
  • Keiyo Takubo, Phyo Wai Htun, Takeshi Ueda, Yasuyuki Sera, Masayuki Iwasaki, Miho Koizumi, Kohei Shiroshita, Hiroshi Kobayashi, Miho Haraguchi, Shintaro Watanuki, et al. MBTD1 preserves adult hematopoietic stem cell pool size and function. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 32. e2206860120
  • Feng Pan, Masayuki Iwasaki, Wenqi Wu, Yanan Jiang, Xin Yang, Li Zhu, Zhigang Zhao, Michael L Cleary. Enhancer remodeling drives MLL oncogene-dependent transcriptional dysregulation in leukemia stem cells. Blood advances. 2023. 7. 11. 2504-2519
  • Miho Koizumi, Hikaru Eto, Mai Saeki, Masahide Seki, Tsuyoshi Fukushima, Shoichiro Mukai, Hisamitsu Ide, Yasuyuki Sera, Masayuki Iwasaki, Yutaka Suzuki, et al. UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022. 36. 12. e22662
  • 村元 啓仁, 岩崎 正幸, 井手 久満, 向井 尚一郎, 片岡 寛章, 武藤 智, 堀江 重郎, 本田 浩章. 遺伝子改変マウスモデルを用いたエピジェネティック変異による前立腺癌発症機構の解明(Elucidation of the pathogenesis of prostate cancer harboring epigenetic mutations using genetically engineered mice). 日本癌学会総会記事. 2022. 81回. J-3039
ｍore...
MISC (5)：
Lectures and oral presentations  (11)：
  • Essential non-canonical role for 15-PGDH in HOX-associated leukemia stem cells
    (2019)
  • Essential non-canonical role for 15-PGDH in MLL-rearranged AML stem cells
    (2019)
  • Essential non-canonical role for 15-PGDH in MLL-rearranged AML stem cells
    (44th IRCMS Seminar 2019)
  • Meis1標的遺伝子による白血病幹細胞の制御機構
    (がん研究会がん研究所セミナー 2018)
  • Essential non-canonical role for 15-PGDH in MLL- rearranged AML stem cells
    (第79回日本血液学会学術集会 2017)
ｍore...
Awards (1)：
  • 2016/11 - 日本白血病研究基金 一般研究賞 MLL遺伝子再構成を伴う急性骨髄性白血病の白血病幹細胞を標的とした新規治療法の開発
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