Research theme for competitive and other funds (14):
2023 - 2027 中枢神経系脆弱性と全身麻酔に関連した周術期認知機能障害の神経病理解析
2022 - 2025 Elucidation of important research issues to be solved in pharmacological research on histamine
2020 - 2023 吸入麻酔薬の意識消失作用におけるニューロテンシン神経系の役割
2017 - 2020 Role of histaminergic nervous system in general anesthesia
2014 - 2018 Analysis of histamine system through genetically modified mice
2016 - 2017 ヒスタミン分解酵素特異的阻害剤のスクリーニング
2015 - 2017 Role of histamine nervous system in inhaled anesthesia.
2017 - 覚醒機能障害に有用なHNMT特異的阻害薬の探索
2014 - Expression and Function of Histamine H3 receptor in Pancreatic Islets
2014 - 2014 The expression analysis of histaminergic nerves in pancreatic isles.
2012 - 2013 膵β細胞特異的ヒスタミン3型受容体欠損マウスの作製及び解析
2012 - 2012 Histamine H3 receptor regulates the functions of pancreatic β-cell.
2011 - 2011 Histamine Receptor H3 Regulates the Function of Pancreatic β-cell.
2011 - 2011 The role of histamine receptor H3 in pancreatic β-cells
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Papers (36):
Fumito Naganuma, Daiki Murata, Marie Inoue, Yuri Maehori, Ryuichi Harada, Shozo Furumoto, Yukitsuka Kudo, Tadaho Nakamura, Nobuyuki Okamura. A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model. Molecular imaging and biology. 2023
Ryota Kobayashi, Tadaho Nakamura, Fumito Naganuma, Ryuichi Harada, Daichi Morioka, Masafumi Kanoto, Shozo Furumoto, Yukitsuka Kudo, Takanobu Kabasawa, Koichi Otani, et al. In vivo [18F]THK-5351 imaging detected reactive astrogliosis in argyrophilic grain disease with comorbid pathology: A clinicopathological study. Journal of neuropathology and experimental neurology. 2023. 82. 5. 427-437
Tadaho Nakamura, Fumito Naganuma, Uta Kudomi, Sueji Roh, Kazuhiko Yanai, Takeo Yoshikawa. Oral histidine intake improves working memory through the activation of histaminergic nervous system in mice. Biochemical and biophysical research communications. 2022. 609. 141-148
Rina Otsuka, Fumito Naganuma, Tadaho Nakamura, Hideki Miwa, Rumi Nakayama-Naono, Takuro Matsuzawa, Yurika Komatsu, Yuki Sato, Yuna Takahashi, Haruna Tatsuoka-Kitano, et al. Contribution of astrocytic histamine N-methyltransferase to histamine clearance and brain function in mice. Neuropharmacology. 2022. 109065-109065
Fumito Naganuma, Tadaho Nakamura, Hiroshi Kuroyanagi, Masato Tanaka, Takeo Yoshikawa, Kazuhiko Yanai, Nobuyuki Okamura. Chemogenetic modulation of histaminergic neurons in the tuberomamillary nucleus alters territorial aggression and wakefulness. Scientific reports. 2021. 11. 1. 17935-17935
Naganuma Fumito, Nakamura Tadaho, Vetrivelan Ramalingam, Yoshikawa Takeo, Okamura Nobuyuki. Neurotensinergic neurons in the lateral hypothalamus are important for physiological sleep-wake cycle. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 3-B-P-185
Nakamura Tadaho, Kimura Takeshi, Naganuma Fumito, Yoshikawa Takeo, Okamura Nobuyuki, Yanagita Toshihiko. Assessment of learning achievement using self-assessment rubric in the role-play for pharmacological education. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 4-B-O13-6
2011/05 - The European Histamine Research Society Young Investigator Award The role of histamine receptor H3 in pancreatic β-cells
2011/01 - 東北大学大学院医学系研究科第4回リトリート大学院生研究発表会 Young Investigator’s poster Award 膵β細胞におけるヒスタミン3型受容体の機能解析
2010/12 - 4th East Asian Pacific Student Workshop on Nano-BME Poster Presentation Award Histamine receptor H3 regulates insulin secretion in mouse pancreatic β-cell line MIN6 cells
2004/03 - 亀田総合病院 ベストジュニアメンター賞
2004/03 - 亀田総合病院 研修医功労賞
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Association Membership(s) (4):
JAPANESE SOCIETY OF ANESTHESIOLOGISTS
, THE JAPANESE NEUROSCIENCE SOCIETY
, THE JAPANESE SOCIETY OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
, THE JAPANESE PHARMACOLOGICAL SOCIETY