Sakamoto Yasuhisa

サカモトヤスヒサ | Sakamoto Yasuhisa

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://www.moroishi-lab.com/

Research field (3)： Cell biology , Functional biochemistry , Medical biochemistry

Research keywords (5)：エンドサイトーシス , 細胞運動 , インテグリン , シグナル伝達 , 細胞膜

Research theme for competitive and other funds (5)：

2024 - 2027 エンドサイトーシスの積荷選別メカニズムの新展開
2019 - 2022 ユビキチン化を介したβ1インテグリンの抑制機構とがん悪性化への関与
2016 - 2017 小胞形成と共役したNedd4L活性化機構の解明
2014 - 2015 細胞膜カーブを介した新しいシグナル伝達複合体のモデル構築
2011 - 2012 Regulatory mechanism of EGF Receptor endocytosis by membrane deformingprotein FCHO2

Papers (16)：

Mayumi Niimura, Yasuhisa Sakamoto, Mayuko Shimoda, Narumi Harada, Ayato Maeda, Shiho Wada, Koki Murata, Saisai Liu, Haruka Ohara, Asuka Iwamoto, et al. Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy. 2024
Chanida Thinyakul, Yasuhisa Sakamoto, Mayuko Shimoda, Yanliang Liu, Suyanee Thongchot, Omnia Reda, Akihiro Nita, Romgase Sakamula, Somponnat Sampattavanich, Ayato Maeda, et al. Hippo pathway in cancer cells induces NCAM1+αSMA+ fibroblasts to modulate tumor microenvironment. Communications biology. 2024. 7. 1. 1343-1343
Yasuhisa Sakamoto, Akiyoshi Uezu, Koji Kikuchi, Jangmi Kang, Eiko Fujii, Toshiro Moroishi, Shiro Suetsugu, Hiroyuki Nakanishi. The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature. The EMBO Journal. 2024
Koji Kikuchi, Yasuhisa Sakamoto, Akiyoshi Uezu, Hideyuki Yamamoto, Kei-ichiro Ishiguro, Kenji Shimamura, Taro Saito, Shin-ichi Hisanaga, Hiroyuki Nakanishi. Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells. Life Science Alliance. 2022. 5. 8. e202201390-e202201390
Tsutomu Fujito, Wataru Ikeda, Shigeki Kakunaga, Yukiko Minami, Mihoko Kajita, Yasuhisa Sakamoto, Morito Monden, Yoshimi Takai. Correction: Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3. Journal of cell biology. 2020. 219. 6

ｍore...

Lectures and oral presentations (11)：

Activation mechanism of ubiquitin ligase Nedd4L
(2022)
ユビキチン化酵素Nedd4Lとアダプター分子ARRDC1によるインテグリンa5b1のユビキチン化を介したエンドサイトーシスの制御
(第42回日本分子生物学会年会 2019)
alpha-arrestin ARRDC1 regulates Nedd4L in concert with membrane curvature
(2016)
F-BARタンパク質を介したEGF受容体の制御機構
(第12回がん若手研究者ワークショップ 2011)
Novel Role of Adenomatous Polyposis Coli: Coordination between Microtubule and Intermediate Filament
(EMBO meeting 2009, Amsterdam, 2009)

ｍore...

Education (3)：

Professional career (1)：

Work history (5)：

Awards (2)：

Association Membership(s) (1)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page