Rchr
J-GLOBAL ID:201601017297586550
Update date: Nov. 17, 2024
Sugimoto Kotaro
スギモト コウタロウ | Sugimoto Kotaro
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.fmu.ac.jp/home/p2/index.html
Research field (3):
Human pathology
, Developmental biology
, Experimental pathology
Research keywords (5):
Cancer
, Stem Cell
, Tissue Regeneration
, Epithelial Differentiation
, Genome Editing
Research theme for competitive and other funds (19):
- 2024 - 2027 クローディン-16を標的とする卵巣癌の新規診断治療法の開発
- 2024 - 2027 網羅的解析で同定されたKLHL14は卵巣癌の新規診断治療標的となりうるか
- 2023 - 2026 核内受容体のリン酸化によるがん悪性形質の新規促進機構の解明
- 2023 - 2026 悪性黒色腫におけるIgSF11の機能解析
- 2022 - 2025 肝癌と膵癌における核内受容体LRH1異常リン酸化の解明
- 2022 - 2025 新規抗CLDN10モノクローナル抗体を活用した腎癌悪性形質制御機構の解明
- 2022 - 2025 口腔扁平上皮癌における肝X受容体異常リン酸化の診断治療標的としての可能性
- 2023 - 2025 SPON1 is a novel prognostic biomarker for ovarian cancer.
- 2021 - 2024 Forward genetic identification of new players in vitamin D signaling.
- 2020 - 2023 幹細胞ニッチシグナルを利用した組織再生新戦略
- 2021 - 2022 Forward genetic analysis to identify novel players in the retioic acid signalling pathway.
- 2020 - 2022 Claudin-Nuclear receptor-axis in breast cancer.
- 2020 - 2021 Forward genetic analysis to identify novel cancer drivers in the retioic acid signalling pathway.
- 2019 - 2021 Cancer cell fates regulated by a newly identified axis of the cell-cell junction and nuclear receptors
- 2017 - 2020 Promotion of cancer progression by aberrant cell adhesion signaling
- 2019 - 2020 Aberrant claudin-6-adhesion signaling promotes cancer progression via ERα
- 2017 - 2019 Regulation of blood-brain barrier by neuro-vascular units and the involvement in schizophrenia
- 2017 - 2019 Identification of the global enhancer elements regudlating epithelial differentiation
- 2011 - 2012 上皮の細胞間接着・極性形成におけるクローディンの役割とその下流シグナル
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Papers (40):
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Kotaro Sugimoto, Toshiki Murakami, Akira Ojima, Tetsuju Sekiryu. Comparison of clinical findings and subjective symptoms in a case of multiple evanescent white dot syndrome (MEWDS): A case report from a patient's perspective. Journal of General and Family Medicine. 2024
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Naoki Ichikawa-Tomikawa, Kotaro Sugimoto, Korehito Kashiwagi, Hideki Chiba. The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling. Cells. 2023. 12. 13
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Atsushi Nishimagi, Makoto Kobayashi, Kotaro Sugimoto, Yasuhide Kofunato, Naoya Sato, Junichiro Haga, Teruhide Ishigame, Takashi Kimura, Akira Kenjo, Yasuyuki Kobayashi, et al. Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence. Clinical and experimental medicine. 2023
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Ryoya Miyakawa, Makoto Kobayashi, Kotaro Sugimoto, Yuta Endo, Manabu Kojima, Yasuyuki Kobayashi, Shigenori Furukawa, Tsuyoshi Honda, Takafumi Watanabe, Shigeyuki Asano, et al. SPON1 is an independent prognostic biomarker for ovarian cancer. Journal of ovarian research. 2023. 16. 1. 95-95
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Yuko Murakami-Nishimagi, Kotaro Sugimoto, Makoto Kobayashi, Kazunoshin Tachibana, Manabu Kojima, Maiko Okano, Yuko Hashimoto, Shigehira Saji, Tohru Ohtake, Hideki Chiba. Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β. Breast cancer research : BCR. 2023. 25. 1. 41-41
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MISC (110):
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杉本 幸太郎, 千葉 英樹. 核内受容体の新規調節機構の発見と病理学への展開. 福島医学雑誌. 2023. 73. 3. 65-71
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峯 勇人, 山口 光, 渡部 晶之, 尾崎 有紀, 武藤 哲史, 岡部 直行, 松村 勇輝, 小林 信, 杉本 幸太郎, 濱田 和幸, et al. 肺癌における核内受容体LRH1異常リン酸化の解明と意義. 日本呼吸器外科学会雑誌. 2023. 37. 3. O7-5
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川名 聡, 山田 匠希, 北條 洋, 杉本 幸太郎, 喜古 雄一郎, 鈴木 理, 大原 喜一, 佐野 秀樹, 橋本 優子. 腎腫瘍の1例. 日本小児血液・がん学会雑誌. 2023. 60. 1. 100-100
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瓜生 開, 小林 信, 杉本 幸太郎, 遠藤 雄大, 小林 靖幸, 田口 歩, 千葉 英樹. 卵巣がんの新規抗体医薬品標的タンパク質の網羅的同定. 電気泳動. 2023. 67. Suppl. s47-s47
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小林 信, 杉本 幸太郎, 瓜生 開, 遠藤 雄大, 小島 学, 千葉 英樹. 二次元電気泳動/ウエスタンブロット法によるがん患者由来自己抗体の新規網羅的同定法. 電気泳動. 2023. 67. Suppl. s58-s58
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Patents (4):
Lectures and oral presentations (75):
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The tight junction-nuclear receptor signalling pathway in physiological and pathological states.
(70th JSPS Annual Meeting 2024)
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細胞性免疫主体の障害が病理で示された、肺小細胞癌に伴う抗NMDA受容体脳炎の72歳女性例
(臨床神経学 2022)
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卵巣癌新規診断マーカーとしてのClaudin-12
(日本病理学会会誌 2022)
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Spondin-1は卵巣癌における新規予後マーカーとなり得る
(日本病理学会会誌 2022)
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Claudin-9は子宮内膜癌の予後不良因子である
(日本病理学会会誌 2022)
more...
Education (2):
- 2010 - 2013 Sapporo Medical University Graduate School of Medicine
- 2002 - 2008 Sapporo Medical University School of Medicine
Professional career (2):
- PhD (Medicine) (Sapporo Medical University)
- MD (Sapporo Medical University)
Work history (5):
- 2019/07 - 現在 Fukushima Medical University Department of Pathology Associate Professor
- 2016/08 - 2019/06 Fukushima Medical University Department of Pathology Assistant Professor/Acting Associate Professor
- 2015/04 - 2016/07 JSPS Research Fellow in Abroad
- 2013/04 - 2016/07 Victor Chang Cardiac Research Institute Cardiac Regeneration Lab Postdoctoral Scientist
- 2011/04 - 2013/03 JSPS Research Fellow, DC2
Awards (10):
- 2024/11 - JSPS Research Award
- 2024/08 - Fukushima Medical University Teacher of the year
- 2022/12 - Fukushima Society of Medical Science Young investigator award
- 2021 - The Japanese Society for Pathology Young Investigator Award
- 2020 - FUKUSHIMA MEDICAL ASSOCIATION Young investigator award
- 2019 - Fukushima Medical University Teacher of the Year 2019
- 2018 - Fukushima Medical University Teacher of the Year 2018
- 2015 - ANZ Zebrafish Meeting Best Talk Award
- 2013 - The Japanese Society of Pathology Rookie Award
- 2007 - JASSO Student Prize
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