Mika Hori

ホリミカ | Mika Hori

Research field (2)： Pathobiochemistry , Metabolism and endocrinology

Research keywords (1)：肝臓

Research theme for competitive and other funds (8)：

2022 - 2027 Exploration of homeostastic regulation of amino acid metabolism-through the analyses of glucagon action and liver zonation.
2022 - 2027 Homeostatic regulation of amino acid metabolism through the viewpoint of glucagon and liver zonation.
2021 - 2024 Elucidation of development of pancreatic neuroendocrine tumors mediated by abnormal amino acid metabolism using a mouse model
2017 - 2020 Elucidation of the effect of variants in the PCSK9 gene and molecular type on lifestyle-related diseases and its regulatory mechanism
2019 - 2019 アキレス腱の軟らかさに着目した家族性高コレステロール血症・新診断法の確立

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Papers (68)：

Yuya Urano, Shinji Mii, Shun Asai, Nobutoshi Esaki, Ryota Ando, Yukihiro Shiraki, Tadashi Iida, Katsuhiro Kato, Mika Hori, Yoshitaka Hayashi, et al. Superoxide dismutase 2 deficiency in mesenchymal stromal cells induces sympathetic denervation and functional impairment of brown adipose tissue. Pathology international. 2025. 75. 2. 69-81
Mika Hori. [Mechanism of the Molecular Pathophysiology for Familial Hypercholesterolemia]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2025. 145. 3. 195-200
Sayaka Funabashi, Yu Kataoka, Mika Hori, Masatsune Ogura, Takahito Doi, Yoshiaki Morita, Eri Kiyoshige, Kunihiro Nishimura, Teruo Noguchi, Mariko Harada-Shiba. Asymptomatic Intracranial Artery Stenosis/Occlusion in Heterozygous Familial Hypercholesterolemia: Its Frequency and Implications for Cerebrovascular and Cardiovascular Events. Journal of the American Heart Association. 2024. 13. 15. e033972
Kotaro Noda, Yorito Hattori, Mika Hori, Mariko Harada-Shiba, Masafumi Ihara. A Case of Multiple Intracranial Major Artery Stenoses With Coexisting PCSK9 p.E32K and RNF213 p.R4810K Variants. Neurology. Genetics. 2023. 9. 5. e200099
Kotaro Noda, Yorito Hattori, Mika Hori, Yuriko Nakaoku, Akito Tanaka, Takeshi Yoshimoto, Kunihiro Nishimura, Takanori Yokota, Mariko Harada-Shiba, Masafumi Ihara. Amplified Risk of Intracranial Artery Stenosis/Occlusion Associated With RNF213 p.R4810K in Familial Hypercholesterolemia. JACC. Asia. 2023. 3. 4. 625-633

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MISC (102)：

浅井敬大, 堀美香, 林良敬. グルカゴンと高蛋白食による肝臓のアミノ酸・脂質代謝とZonationへの影響に関する解析. 糖尿病. 2024. 67. Suppl.1. S-289
村田博朗, 服部頼都, 堀美香, 野田浩太郎, 中奥由里子, 中奥由里子, 尾形宗士郎, 長井篤, 山口修平, 斯波真理子. 家族性高コレステロール血症と脳小血管病との関連についての検討. 日本脳ドック学会総会プログラム・抄録集. 2024. 33rd
堀美香, 堀美香. Mechanism of the molecular pathophysiology for familial hypercholesterolemia. 日本薬学会年会要旨集(Web). 2024. 144th. 3. 195-200
堀美香, 五島直樹, 浅井敬大, 林良敬. グルカゴン遺伝子欠損マウスの脂肪肝抵抗性とzonationに関する解析. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2024. 56th. 295-295
舟橋紗耶華, 舟橋紗耶華, 片岡有, 堀美香, 堀美香, 小倉正恒, 小倉正恒, 野口暉夫, 斯波真理子, 斯波真理子. 家族性高コレステロール血症の心血管疾患一次予防におけるリスク層別化法の検証. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2024. 56th. 217-217

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Patents (1)：

Work history (7)：

2020/07 - 現在 National Cerebral and Cardiovascular Center, Research Institute
2020/07 - 現在 Research Institute of Environmental Medicine, Nagoya University Department of Endocrinology
2017/01 - 2020/06 National Cerebral and Cardiovascular Center Research Institute Department of Molecular Innovation in Lipidology
2015/04 - 2016/12 National Cerebral and Cardiovascular Center Research Institute Department of Molecular Innovation in Lipidology
2011/09 - 2015/03 National Cerebral and Cardiovascular Center Research Institute Department of Molecular Innovation in Lipidology

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Committee career (6)：

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Awards (9)：

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Association Membership(s) (5)：

日本循環器学会 , 日本がん予防学会 , 日本分子生物学会 , 日本癌学会 , 日本動脈硬化学会

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