Rchr
J-GLOBAL ID:201601019789365047   Update date: Mar. 11, 2024

Mizutani Kenji

ミズタニ ケンジ | Mizutani Kenji
Affiliation and department:
Research field  (2): Molecular biochemistry ,  Structural biochemistry
Research keywords  (10): タンパク質のリデザイン ,  ウイルスタンパク質 ,  タンパク質構造固定化 ,  タンパク質工学 ,  タンパク質の熱分析 ,  分析超遠心 ,  V型ATPase ,  膜タンパク質 ,  X線結晶構造解析 ,  Structural Biology
Research theme for competitive and other funds  (3):
  • 2018 - 2021 Structural study of infection molecular mechanism of the mouse norovirus.
  • 2014 - 2017 Molecular mechanism of the structural formation and functional regulation of the V1 rotary motor
  • 2011 - 2014 Structural basis of ATP hydrolysis mechanism of V1-ATPase motor
Papers (29):
  • Kenta Arai, Masaki Okumura, Young-Ho Lee, Hidekazu Katayama, Kenji Mizutani, Yuxi Lin, Sam-Yong Park, Kaichiro Sawada, Masao Toyoda, Hironobu Hojo, et al. Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity. Communications chemistry. 2023. 6. 1. 258-258
  • Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R H Tame, Asuka Inoue, Sam-Yong Park. Structural basis of CXC chemokine receptor 1 ligand binding and activation. Nature communications. 2023. 14. 1. 4107-4107
  • Rawiwan Wongnak, Subbaian Brindha, Takahiro Yoshizue, Sawaros Onchaiya, Kenji Mizutani, Yutaka Kuroda. E. coli production of a multi-disulfide bonded SARS-CoV-2 Omicron BA.5 RBD exhibiting native-like biochemical and biophysical properties. Biophysics and physicobiology. 2023. 20. 4. e200036
  • Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, et al. Structural insights into the HBV receptor and bile acid transporter NTCP. Nature. 2022. 606. 7916. 1027-1031
  • Sawaros Onchaiya, Tomonori Saotome, Kenji Mizutani, Jose C Martinez, Jeremy R H Tame, Shun-Ichi Kidokoro, Yutaka Kuroda. Reverse Engineering Analysis of the High-Temperature Reversible Oligomerization and Amyloidogenicity of PSD95-PDZ3. Molecules (Basel, Switzerland). 2022. 27. 9
more...
MISC (6):
Patents (1):
  • HEAT STABILIZATION MUTANT PREDICTOR, HEAT STABILIZATION MUTANT PREDICTION METHOD, AND PROGRAM
Books (2):
  • 骨研究最前線 : 代謝・疾病のメカニズムから再生医療・創薬・リハビリ機器・機能性食品開発まで
    エヌ・ティー・エス 2013 ISBN:9784864690782
  • 膜タンパク質構造研究
    化学同人 2013
Professional career (1):
  • 博士(理学) (横浜市立大学)
Committee career (1):
  • 2017/04 - 2019/03 PF news 編集委員会 PF外部編集委員
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