Research theme for competitive and other funds (3)：
2018 - 2021 Structural study of infection molecular mechanism of the mouse norovirus.
2014 - 2017 Molecular mechanism of the structural formation and functional regulation of the V1 rotary motor
2011 - 2014 Structural basis of ATP hydrolysis mechanism of V1-ATPase motor
Papers (30)：
Thao Tu, Tharangani Rathnayaka, Toshiyo Kato, Kenji Mizutani, Tomonori Saotome, Keiichi Noguchi, Shun-Ichi Kidokoro, Yutaka Kuroda. Design and Escherichia coli Expression of a Natively Folded Multi-Disulfide Bonded Influenza H1N1-PR8 Receptor-Binding Domain (RBD). International journal of molecular sciences. 2024. 25. 7
Kenta Arai, Masaki Okumura, Young-Ho Lee, Hidekazu Katayama, Kenji Mizutani, Yuxi Lin, Sam-Yong Park, Kaichiro Sawada, Masao Toyoda, Hironobu Hojo, et al. Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity. Communications chemistry. 2023. 6. 1. 258-258
Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R H Tame, Asuka Inoue, Sam-Yong Park. Structural basis of CXC chemokine receptor 1 ligand binding and activation. Nature communications. 2023. 14. 1. 4107-4107
Rawiwan Wongnak, Subbaian Brindha, Takahiro Yoshizue, Sawaros Onchaiya, Kenji Mizutani, Yutaka Kuroda. E. coli production of a multi-disulfide bonded SARS-CoV-2 Omicron BA.5 RBD exhibiting native-like biochemical and biophysical properties. Biophysics and physicobiology. 2023. 20. 4. e200036
Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, et al. Structural insights into the HBV receptor and bile acid transporter NTCP. Nature. 2022. 606. 7916. 1027-1031
