Hitomi Aoki

Affiliation and department：
Job title：講師

Research field (3)： Cell biology , Anatomy , Developmental biology

Research keywords (13)：予防・治療・再生 , 実験動物モデル , CoCl2 , 網膜視細胞障害 , Apoptosis , 神経幹細胞 , Rest , 遺伝子組換え , 分子・細胞神経科学 , 発生神経科学 , 発生 , 分化 , 神経堤細胞

Research theme for competitive and other funds (12)：

2018 - 2023 色素幹細胞を用いた神経分化抑制因子Restの幹細胞因子としての機能解明
2019 - 2022 Maintenance of melanocyte stem cell function by HMGB2 gene expressed in hair follicles.
2017 - 2020 Analysis of cancer-associated cells in the microenvironment of pancreatic cancer : Aim to suppress metastasis
2016 - 2019 Analysis of niche factors for melanocyte stem cells
2014 - 2017 Analysis of hepatic stem and progenitor cells in the tumor microenvironment of liver metastasis: For cancer metastasis suppression

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Papers (63)：

Hitomi Aoki, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada. Conditional heterozygous loss of Kit receptor tyrosine kinase in neural crest cell lineage is associated with midline cleft lip and bifid nose deformity. Journal of oral biosciences. 2024
Hitomi Aoki, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada. Postnatal Expression of Kitl Affects Pigmentation of the Epidermis. The Journal of investigative dermatology. 2023
Takashi Satake, Shingo Komura, Hitomi Aoki, Akihiro Hirakawa, Yuuki Imai, Haruhiko Akiyama. Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells. BMC Molecular and Cell Biology. 2022. 23. 1
Motoki Takenaka, Tatsuro Furui, Noriko Suzuki, Tiger Koike, Hitomi Aoki, Ken-Ichirou Morishige. Glutathione as a Prognostic Biomarker and a Potential Therapeutic Target for Ovarian Cancer. Open Journal of Obstetrics and Gynecology. 2022. 12. 01. 56-66
Hironao Ichikawa, Atsushi Suetsugu, Tomoyuki Satake, Hitomi Aoki, Takahiro Kunisada, Masahito Shimizu, Robert M. Hoffman. Exosome transfer between pancreatic-cancer cells is associated with metastasis in a nude-mouse model. Anticancer Research. 2021. 41. 6. 2829-2834

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MISC (82)：

河村真吾, 佐竹崇志, 後藤篤史, 平川明弘, 秋山治彦, 青木仁美, 柴田博史, 伊藤謙治, 山田泰広. マウスiPS細胞由来腱様細胞は腱損傷部の再生を促進する. 日本手外科学会雑誌. 2021. 38. 1. PD2-4
河村真吾, 佐竹崇志, 後藤篤史, 平川明弘, 秋山治彦, 青木仁美, 柴田博史, 伊藤謙治, 山田泰広. マウスiPS細胞由来腱様細胞は腱損傷部の再生を促進する. 日本整形外科学会雑誌. 2021. 95. 2. S120-S120
河村真吾, 佐竹崇志, 後藤篤史, 青木仁美, 柴田博史, 伊藤謙治, 平川明弘, 山田泰広, 秋山治彦. マウスiPS細胞由来腱様細胞は腱損傷部の再生を促進する. 日本整形外科学会雑誌. 2020. 94. 8. S1930-S1930
小足周平, 青木仁美, 柴田敏之, 國貞隆弘, 手塚建一, 澁谷俊昭. ZFNを用いたヒト歯髄細胞におけるHLAゲノムエディティング. 日本歯周病学会会誌. 2018. 60. 春季特別. 126-126
H. Aoki, T. Kunisada. Induced haploinsufficiency of kit receptor tyrosine kinase impairs development of central nervous system. JOURNAL OF NEUROCHEMISTRY. 2017. 142. 137-137

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Patents (5)：

Books (5)：

Lectures and oral presentations (21)：

神経堤細胞から色素細胞への運命決定の過程でのRest欠損による白斑形成
(第26回日本色素細胞学会 2015)
Rest function in neuronal or neural crest cell lineage revealed by the conditional gene ablation
(第58回日本神経化学会大会 2015)
Keratinocyte stem cells as a primary target for radiation-induced hair graying
(第24回日本色素細胞学会 2012)
Rest is dispensable for the proper intrinsic regulations of neuronal gene expression in the specification of cell fate during neurogenesis in vivo
(第44回日本発生生物学会年会 2011)
色素細胞幹細胞への遺伝毒性ストレスに対する色素細胞分化増殖因子の影響
(第23回日本色素細胞学会 2010)

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Education (1)：

Professional career (1)：

Work history (2)：

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