Watanabe Toshiaki

Affiliation and department：

Research field (3)： Developmental biology , Genetics , Molecular biology

Research keywords (8)：霊長類精巣構築 , iPS細胞 , ゲノム恒常性 , Spermatogonial Stem Cells , stem cells , marmoset , primates , germ cells

Research theme for competitive and other funds (7)：

2023 - 2028 genome stability for the next generation
2022 - 2026 Antiaging mechanisms in primate spermatogonial stem cells
2022 - 2025 Constructing primate testes in mice by replacing testicular cells
2020 - 2023 Generation of genetically modified primates using cultured germ cells
2020 - 2023 Development of novel techniques for generation of genome engineering marmosets

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Papers (30)：

Musashi Kubiura-Ichimaru, Christopher Penfold, Kazuaki Kojima, Constance Dollet, Haruka Yabukami, Katsunori Semi, Yasuhiro Takashima, Thorsten Boroviak, Hideya Kawaji, Knut Woltjen, et al. mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells. Stem Cell Reports. 2023. 18. 10. 1987-2002
Toshiaki Watanabe, Erika Sasaki. Efficient Induction of Primate iPS Cells Using a Combination of RNA Transfection and Chemical Compounds. Methods in molecular biology (Clifton, N.J.). 2022. 2454. 685-696
Tomoo Eto, Hiroki Ueda, Ryoji Ito, Tsukasa Takahashi, Toshiaki Watanabe, Motohito Goto, Yusuke Sotomaru, Nobuaki Tanaka, Riichi Takahashi. Establishment of an integrated automated embryonic manipulation system for producing genetically modified mice. Scientific reports. 2021. 11. 1. 11770-11770
Toshiaki Watanabe, Shun Yamazaki, Nao Yoneda, Haruka Shinohara, Ikuo Tomioka, Yuichiro Higuchi, Mika Yagoto, Masatsugu Ema, Hiroshi Suemizu, Kenji Kawai, et al. Highly efficient induction of primate iPS cells by combining RNA transfection and chemical compounds. Genes to cells : devoted to molecular & cellular mechanisms. 2019. 24. 7. 473-484
KAWAI Jun, NAKAYA Masataka, SASAKI Erika, INOUE Takashi, WATANABE Toshiaki, SAKAKIBARA Yasubumi, JAYAKUMAR Vasanthan, NAITO Yuki, MURAKAWA Yasuhiro, KAWAJI Hideya, et al. Primate DNA/RNA database; development and application for medicine. Annual Meeting of the Japanese Society of Toxicology. 2019. 46. S15-4

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MISC (20)：

小島一晃, 圦本晃海, 向笠圭亮, 井上貴史, 黒滝陽子, 佐々木えりか, 渡部聡朗. Single cell analyses of the establishment of DNA methylation in primate marmoset male germ cells. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
小島一晃, 藪上春香, 圦本晃海, 峰重隆幸, 井上貴史, 喜多善亮, 黒滝陽子, 下郡智美, 川路英哉, 蓑田亜希子, et al. 霊長類マーモセット雄性生殖幹細胞におけるPIWI-piRNA機構の解析. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
河合純, 廣瀬直毅, 佐野浩美, 岡崎康司, 八木研, 山本由美子, 依馬正次, 清田弥寿成, 築山智之, 中家雅隆, et al. DNA/RNAを標的とする医療技術の現状と安全性評価の考え方霊長類DNA/RNAデータベースの構築と医療への応用. The Journal of Toxicological Sciences. 2019. 44. Suppl. S96-S96
渡部聡朗, 藪上春香, 井上貴史, 峰重隆幸, 圦本晃海, 黒滝陽子, 喜多善亮, 下郡智美, 川路英哉, 蓑田亜希子, et al. マーモセット生殖細胞発生におけるDNAメチル化制御. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
渡部聡朗, 藪上春香, 井上貴史, 峰重隆幸, 圦本晃海, 黒滝陽子, 川路英哉, 蓑田亜希子, 佐々木えりか. マーモセット生殖細胞発生の理解. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st

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Lectures and oral presentations (4)：

Education (3)：

Work history (5)：

2022/04 - 現在 National Center for Child Health and Development
2017/04 - 2022/03 Central Institute for Experimental Animals Department of marmoset biology and medicine Researcher
2016/10 - 2017/03 Kyoto Univeristy School of Medicine Assistant Professor
2010/03 - 2016/09 Yale University Postdoctoral researcher
2009/04 - 2010/02 National Institute of Genetics Researcher

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