Ngo Kien Xuan

• 2023 - 2026 Grants-in-Aid for Scientific Research (JSPS) (type B 23H02452-01) The mechanism of sparsely coupled actin-binding proteins regulate the function of the entire actin filament.
• 2023 - 2026 Grants-in-Aid for Scientific Research (JSPS) (type C-23K05713)-Structures and dynamics of ABC transporters MsbA and LptB2FG in working with LptC during transport activities
• 2022 - 2025 BIO-SPM Research Collaborative Fund FY2022- Pore formation of alpha-toxin from Staphylococcus aureus and its toxoids investigated by Atomic Force Microscopy
• 2018 - 2025 Kanazawa University Fund [Strategic Research Promotion Program (Core-to-Core Program)]
• 2022 - 2023 WPI NanoLSI TDRP - Temperature-modulated supramolecular nanomachinery for manipulating programmed cell death
2019 - 2022 Grants-in-Aid for Scientific Research (JSPS) (type C)-Project No. 19K06581
2020 - 2021 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2019 - 2020 BIO-SPM Research Collaborative Fund FY2019
2019 - 2020 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2018 - 2019 BIO-SPM Research Collaborative Fund FY2018
2018 - 2019 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2018 - 2019 WPI-NanoLSI Startup
2012 - 2017 Actin structural polymorphism machinery that orchestrates amoeba motility
2012 - 2017 Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

• Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro Q.P. Uyeda. Deciphering the actin structure-dependent preferential cooperative binding of cofilin. eLife. 2024
• Tareg Omer Mohammed, You-Rong Lin, Lucky Akter, Kai Weissenbruch, Kien Xuan Ngo, Yanjun Zhang, Noriyuki Kodera, Martin Bastmeyer, Yusuke Miyanari, Azuma Taoka, et al. S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry. Journal of Cell Science. 2024
• Toshio Ando, Shingo Fukuda, Kien X. Ngo, Holger Flechsig. High-Speed Atomic Force Microscopy for Filming Protein Molecules in Dynamic Action. Annual Review of Biophysics. 2023. 53. 1. 19-39
• Yuuki Hayakawa, Masak Takaine, Kien Xuan Ngo, Taiga Imai, Masafumi D Yamada, Arash Badami Behjat, Kenichi Umeda, Keiko Hirose, Ayhan Yurtsever, Noriyuki Kodera, et al. Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II. Life Science Alliance. 2023. 6. 1. e202201469-e202201469
• Kien Xuan Ngo, Phuong Doan N. Nguyen, Hirotoshi Furusho, Makoto Miyata, Tomomi Shimonaka, Nguyen Ngoc Bao Chau, Nguyen Phuong Vinh, Nguyen Anh Nghia, Tareg Omer Mohammed, Takehiko Ichikawa, et al. Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity. Phytopathology®. 2022

ｍore...

• Uni-directional Propagation of Structural Changes in Actin Filaments.” The Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery
  Springe Nature Singapore 2018

• Deciphering the actin structure-dependent preferential cooperative binding of cofilin
  (The 61st Annual Meeting of the Biophysical Society of Japan, Nagoya, Japan 2023)
• Deciphering actin structure-dependent preferential cooperative binding of cofilin
  (The 7th NanoLSI Symposium in Berlin, Germany 2023)
• High-Speed Atomic Force Microscopy for Exploring Nano Life Sciences
  (The 6th International Biology Conference, Quy Nhon, Vietnam 2023)
• Deciphering the actin structure-dependent preferential cooperative binding of cofilin
  (The First International Symposium of Nano Life Science: Nanobiotechnology, Biosensor, Computation (NanoBioCoM2023), Quy Nhon, Vietnam 2023)
• Elucidating the process of pore formation by alpha-hemolysin on lipid membranes using High-speed Atomic Force Microscopy
  (The First International Symposium of Nano Life Science: Nanobiotechnology, Biosensor, Computation (NanoBioCoM2023), Quy Nhon, Vietnam 2023)

ｍore...

• 2005 - 2009 Osaka University, Japan Chemical Engineering Science PhD
• 2003 - 2005 Osaka University, Japan Chemical Engineering Science Master
• 1996 - 2000 Vietnam National University of Agriculture (VNUA) Food Science and Technology Bachelor

• PhD (Grad. Eng. Sci., Osaka University)

• 2018/04 - 現在 Kanazawa University, Japan Nano Life Science Institute (WPI-NanoLSI) Assistant Professor
• 2017/04 - 2018/03 RIKEN, Japan Brain Science Institute Research Scientist
• 2016/04 - 2017/03 Waseda University, Japan Department of Physics, Faculty of Science and Engineering Senior Researcher
• 2013/05 - 2016/03 National Institute of Advanced Industrial Science and Technology (AIST) Biomedical Research Institute, Cell Mechanics Research Group Postdoctoral Special Researcher
• 2011/07 - 2013/04 University of Geneva, Switzerland Faculty of Sciences, Department of Inorganic and Analytical Chemistry Postdoctoral Research Assistant
2009/11 - 2011/06 National Institute of Advanced Industrial Science and Technology (AIST) Biomedical Research Institute, Cell Mechanics Research Group Postdoctoral Special Researcher
2006/04 - 2009/03 Graduate School of Engineering Science, Osaka University JSPS Fellowship (DC1) Doctoral Students
2001/01 - 2003/09 Vietnam Institute of Post Harvest Technology, Hanoi, Vietnam. Department of Microbiology Junior Researcher

• 2024/09 - Co-Chairmans - The Second International Symposium of Nano Life Science (NanoBioCoM 2024)
• 2024/08 - Rencontres du Vietnam Co-Organizers - Materials Informatics: Accelerating Materials Research and Design with Artificial Intelligence
• 2024/06 - The Vietnamese Biophysical Society (VBS) A representative for the Vietnamese Biophysical Society (VBS) to attend the IUPAB Assembly Congress in Kyoto IUPAB in June 2024 VBS becomes an adhering Body of IUPAB
• 2023/09 - Travel Award WPI Nano Life Science Institute, Kanazawa University Travel Award to organize and attend NanoBioCoM2023
• 2023/09 - Co-Chairmans - The First International Symposium of Nano Life Science (NanoBioCoM2023)
2022/07 - American Phytopathology Society (APS) Editor's Pick from July Issue of Phytopathology Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity
2021/02 - RIKEN RIKEN Press Elucidation of the molecular mechanism by which microtubules are produced - Only a few linear oligomers become microtubules
2016/11 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin
2015/02 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy
2010/11 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release.
2006/04 - Grant in Aid for Scientific Research (JSPS), Japan JSPS Fellowship DC1
2003/10 - Vietnamese Government A fully qualified scholarship from Vietnamese Government for studying oversea

The Vietnamese Biophysical Society (VBS) ,  American Phytopathological Society (APS) ,  Swiss Laboratory Animal Science Association ,  Swiss Soft Days Organization ,  Swiss Chemical Society ,  American Biophysical Society ,  The Biophysical Society of Japan (BSJ) ,  The Society for Chemical Engineers, Japan (SCEJ) ,  The Society of Separation Process Engineers, Japan (SSPEJ) ,  The Society for Biotechnology, Japan (SBJ)