Rchr
J-GLOBAL ID：201601020628903659   Update date: Jan. 31, 2024

Muraoka Takahiro

ムラオカ タカヒロ | Muraoka Takahiro
Affiliation and department：
Tokyo University of Agriculture and Technology

About Tokyo University of Agriculture and Technology


Other affiliations (1)：
Homepage URL  (2)： https://www.muraoka-lab.com ,  https://www.muraoka-lab.com/blank-1
Research field  (1)： Biochemistry
Research keywords  (9)： Peptides ,  Molecular Machines ,  Ion Channels ,  Liposome ,  Amphiphiles ,  Photoresponsive Molecules ,  Protein Folding ,  Supramolecular Chemistry ,  Organic Synthesis
Research theme for competitive and other funds  (14)：
  • 2021 - 2024 Development of kinetics-controlling molecules for construction of asymmetric structures
  • 2021 - 2024 Organization of kinetics-driven supramolecular chemistry
  • 2021 - 2024 Kinetics-Driven Supramolecular Chemistry
  • 2021 - 2024 光トランスフェクション法の開発
  • 2021 - 2023 Development of a novel biomolecule delivery system for the establishment of high productivity mutant strains
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Papers (60)：
  • Yoshika Hara, Atsuya Yaguchi, Hirotsugu Hiramatsu, Takahiro Muraoka. ROS-Triggered Gel-Sol Transition and Kinetics-Controlled Cargo Release by Methionine-Containing Peptides. ChemBioChem. 2023. 24. 9
  • Yuya Ohno, Chikako Nakajima, Itsuki Ajioka, Takahiro Muraoka, Atsuya Yaguchi, Teppei Fujioka, Saori Akimoto, Misaki Matsuo, Ahmed Lotfy, Sayuri Nakamura, et al. Amphiphilic peptide-tagged N-cadherin forms radial glial-like fibers that enhance neuronal migration in injured brain and promote sensorimotor recovery. Biomaterials. 2023. 294. 122003-122003
  • Noriyuki Uchida, Yunosuke Ryu, Yuichiro Takagi, Ken Yoshizawa, Kotono Suzuki, Yasutaka Anraku, Itsuki Ajioka, Naofumi Shimokawa, Masahiro Takagi, Norihisa Hoshino, et al. Endocytosis-Like Vesicle Fission Mediated by a Membrane-Expanding Molecular Machine Enables Virus Encapsulation for In Vivo Delivery. Journal of the American Chemical Society. 2023. 145. 11. 6210-6220
  • Adam Wawro, Takahiro Muraoka, Wijak Yospanya, Mayu Kawame, Yudai Nakagawa, Mihoko Ui, Pawel Antonik, Peter Crowley, Kouhei Tsumoto, Kazushi Kinbara. Amphiphilic structured PEG derivatives suppressing protein thermal aggregation at extremely low molecular ratio. 2023
  • Shunsuke Okada, Yosuke Matsumoto, Rikana Takahashi, Kenta Arai, Shingo Kanemura, Masaki Okumura, Takahiro Muraoka. Semi-enzymatic acceleration of oxidative protein folding by N-methylated heteroaromatic thiols. Chemical Science. 2023
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MISC (24)：
  • 松本陽佑, 松崎元紀, 稲葉謙次, 奥村正樹, 村岡貴博, 村岡貴博. Promotion effects of aromatic compounds on oxidative protein folding. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
  • 岡田隼輔, 松崎元紀, 稲葉謙次, 奥村正樹, 村岡貴博. Structural Effects of Reducing Agents on Acceleration of Oxidative Protein Folding. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • 松本陽佑, 松崎元紀, 稲葉謙次, 奥村正樹, 村岡貴博. Substituent effects of redox-active compounds for promotion of oxidative protein folding. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • 岡田隼輔, 松崎元紀, 稲葉謙次, 奥村正樹, 村岡貴博. Development of Novel Thiol-Based Protein Folding Promotors. 日本化学会春季年会講演予稿集(CD-ROM). 2020. 100th
  • 山田千聖, WAWRO Adam, WAWRO Adam, 黒木喜美子, 高橋愛実, 村岡貴博, 村岡貴博, 金原数, 金原数, 前仲勝実. PEG化タンパク質精製法の確立に向けた新規構造化PEG分子の設計と機能解析. 日本生化学会大会(Web). 2017. 2017年度. [3P-0167]
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Patents (6)：
  • Protein aggregation inhibitor, and protein aggregation inhibition method
  • Hetero type monodispersed polyethylene glycol, intermediate for production of hetero type monodispersed polyethylene glycol, methods for producing same, and hetero type monodispersed polyethylene glycol conjugate
  • 芳香環とオリゴエチレングリコールの交互配列からなる新規タンパク質凝集抑制剤
  • タンパク質の凝集抑制剤及びタンパク質の凝集抑制方法
  • ヘテロ型単分散ポリエチレングリコール、ヘテロ型単分散ポリエチレングリコール製造用中間体及びそれらの製造方法、並びに、ヘテロ型単分散ポリエチレングリコール結合体
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Books (1)：
  • Molecular Technology for Membrane Functionalization in Molecular Technology, Volume 2: Life Innovation
    Wiley 2018
Lectures and oral presentations  (60)：
  • Macroscopic Membrane Deformation by Stimuli-responsive Functional Molecules
    (pi-EJ 2019 2019)
  • Development of Membrane Penetrating Substances for Bacteria
    (pi-EJ 2019 2019)
  • Morphological Changes of Self-assembled Structures by Single-Bond Rotating Motion
    (pi-EJ 2019 2019)
  • All-atom molecular dynamics simulations of artificial ion channels
    (情報計算化学生物学会(CBI学会2019年大会) 2019)
  • Development of Membrane Penetrating Substances for Microbes
    (CSJ化学フェスタ 2019)
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Education (3)：
  • 2004 - 2007 The University of Tokyo Graduate School of Engineering Department of Chemistry and Biotechnology
  • 2002 - 2004 The University of Tokyo Graduate School of Engineering Department of Chemistry and Biotechnology
  • 1998 - 2002 The University of Tokyo School of Engineering Faculty of Chemistry and Biotechnology
Professional career (1)：
  • Ph. D. (The University of Tokyo)
Work history (6)：
  • 2013/10/01 - 2017/03/31 Japan Science and Technology Agency PRESTO(Precursory Research for Embryonic Science and Technology) PRESTO Researcher
  • 2015/05/01 - 2017/01/31 Tokyo Institute of Technology School of Life Science and Technology Assistant Professor
  • 2008/05/01 - 2015/04/30 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Assistant Professor
  • 2007/04/01 - 2008/04/30 The Japan Society for the Promotion of Science JSPS Researcher (Research Fellowship for Young Scientists)
  • 2006/07/06 - 2008/04/30 Northwestern University Department of Chemistry Visiting Scholar
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Awards (16)：
  • 2019/09/01 - マツダ財団 マツダ研究助成奨励賞 選択的分子捕捉材料の開発と応用
  • 2018/10/16 - エスペック 公益信託 第21回エスペック地球環境研究奨励賞
  • 2018/10/15 - 東京農工大学 学長賞
  • 2018/06/01 - 天野エンザイム科学技術振興財団 一般財団法人 天野エンザイム科学技術振興財団 第19回酵素応用シンポジウム 研究奨励賞
  • 2016/08/05 - 東京工業大学 平成28年度 東京工業大学 挑戦的研究賞
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Association Membership(s) (6)：
日本化学会 ,  高分子学会 ,  American Chemical Society ,  繊維学会 ,  日本蛋白質科学会 ,  日本微生物生態学会
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