- 2021 - 2024 栄養環境がもたらすエピゲノム制御変化の解明に基づく肝発癌増殖進展の制御
- 2018 - 2021 Investigation on prediction for medical treatment response to advanced hepatocellular carcinoma
- 2018 - 2021 Analysis of metabolic reprogramming induced by cellular environment and its application to control hepato-carcinogenesis
- 2017 - 2020 Regulation of invasion and metastasis of colon cancer via Wnt-Cdh1 axis
- 2014 - 2017 molecular biological analysis of Sessile serrated adenoma/polyp in the proximal colon
- 2014 - 2017 The role of Cdh1 in colorectal cancer invasion and metastasis
- 2013 - 2017 Analysis of microenvironment-mediated treatment resistance of hepatocellular carcinoma in terms of integrated proteomics
- 2014 - 2015 Identification of hepatic maturation mechanisms of human iPS cells by using chemical screening
- 2012 - 2015 Basic study of the cell cycle related molecules affiliated with liver regeneration and clinical application
- 2011 - 2013 The role of cell cycle regulator Cdh1 in carcinogenesis and development of gastrointestinal cancer.
- 2009 - 2012 Analysis of mechanisms underlying treatment-resistance ofhepatocelluar carcinoma in the point view of post-translationalmodification evaluated by proteomics
- 2009 - 2011 The basic analysis of cell cycle association molecules by controlling the function aiming at application to liver regeneration treatment.
- 2007 - 2008 The basic analysis of cell cycle association molecules by controlling the function aiming at application to liver regeneration treatment
- 2006 - 2008 Analysis of molecular mechanisms underlying apoptosis resistance of hepatocellular carcinoma using proteomics
- 2005 - 2006 Mechanism of Apoptosis Induction by Bacterial Proteases and Its Implication for Bacterial Pathogenesis.
- 2004 - 2006 消化管アミロイドーシスの進展抑制を目指した免疫療法の開発
- 2002 - 2004 Analysis of survival signaling and its application for a new therapeutic strategy of cancers in gastro-intestinal tract and liver.
- 2002 - 2003 新規接着因子ninjurinの強制発現を用いたsenescence分子機構の解明
- 2001 - 2003 肝細胞癌に対する腫瘍免疫学的制御の分子機構解析
- 2000 - 2001 Therapeutic strategy for hepatocellular carcinoma by dendritic cell-based tumor vaccination
- 1999 - 2000 Application of Ninjurin, a novel adhesion molecule, to diagnosis and therapeutics of primary hepatocellular carcinoma
- 1999 - 2000 Therapetic strategy for chronic hepatitis C by inducing apoptosis of hepatocyte infected with hepatitis C virus
- 1998 - 2000 Analysis of the molecular mechanism of hepatocarcinogenesis in patients with chronic viral diseases and its application for genetic diagnosis of hepatocellular carcinoma.
- 1996 - 1997 Analysis of the mechanism of liver damage and carcinogenesis in patients with chronic hepatitis C virus infection.
- 1995 - 1996 Basic study for gene therapy of human liver cancer in terms of regulating signal trnasduction pathway
- 1994 - 1995 Biomolecular analysis of liver carcinogenesis in hepatitis C virus infection.
- 1994 - 1995 Investigation for induction of apoptosis-related genes in hepatitis C virus-infected hepatocytes.
- 1987 - 1988 Analysis of inhibitory mechanism by ethanol on liver regeneration.
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