Kato Hideaki

カトウヒデアキ | Kato Hideaki

Affiliation and department：
Job title：准教授
Homepage URL (1)： http://park.itc.u-tokyo.ac.jp/hekato_lab/english_home.html

Research field (3)： Functional biochemistry , Biophysics , Structural biochemistry

Research keywords (7)： protein engineering , オプトジェネティクス , GPCR , ロドプシン , 電子顕微鏡 , X線結晶構造解析 , 構造生物学

Research theme for competitive and other funds (13)：

2023 - 2028 生体磁気センシング機構を利用した細胞自在操作技術の開発と応用
2022 - 2027 The analysis of structural dynamics of microbial rhodopsins
2022 - 2025 Structural and functional analysis of novel transporter-type rhodopsin
2021 - 2025 Manipulation of G12/13 signaling and and drug development strategy
2021 - 2024 Neural representation of "Death" (general affairs)

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Papers (36)：

Seiya Tajima, Yoon Seok Kim, Masahiro Fukuda, YoungJu Jo, Peter Y Wang, Joseph M Paggi, Masatoshi Inoue, Eamon F X Byrne, Koichiro E Kishi, Seiwa Nakamura, et al. Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell. 2023
Koichiro E Kishi, Hideaki E Kato. Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels. Current opinion in structural biology. 2023. 79. 102562-102562
Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Hirotake Miyauchi, Atsuhiro Tomita, Kan Kobayashi, Wataru Shihoya, Keitaro Yamashita, Tomohiro Nishizawa, Hideaki E Kato, et al. Endogenous ligand recognition and structural transition of a human PTH receptor. Molecular cell. 2022. 82. 18. 3468-3483
Koichiro E Kishi, Yoon Seok Kim, Masahiro Fukuda, Masatoshi Inoue, Tsukasa Kusakizako, Peter Y Wang, Charu Ramakrishnan, Eamon F X Byrne, Elina Thadhani, Joseph M Paggi, et al. Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine. Cell. 2022
Naotaka Tsutsumi, Shoji Maeda, Qianhui Qu, Martin Vögele, Kevin M. Jude, Carl-Mikael Suomivuori, Ouliana Panova, Deepa Waghray, Hideaki E. Kato, Andrew Velasco, et al. Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins. Science Advances. 2022. 8. 3

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MISC (8)：

加藤英明. 構造生物学を学ぶ新規イオンチャネル型ロドプシンChRmineの構造機能解析と光遺伝学ツール開発. 日本腎臓学会誌. 2022. 64. 3. 174-174
小林和弘, 川上耕季, 草木迫司, 郷野弘剛, 富田敦弘, 小林幹, 志甫谷渉, 山下恵太郎, 山下恵太郎, 西澤知宏, et al. PTH1受容体における内在性リガンドの認識機構と構造ダイナミクス. 日本生化学会大会(Web). 2022. 95th
平泉将浩, 熊崎薫, MATURANA Andres D., 中根崇智, 西澤知宏, 加藤英明, 加藤英明, 名倉淑子, 岩田想, 伊藤耕一, et al. 小胞体Ca²⁺恒常性に関わるイオンチャネルのX線結晶構造解析. 日本結晶学会年会講演要旨集. 2015. 2015
平泉将浩, 熊崎薫, ANDRES Maturana Daniel, 中根崇智, 西澤知宏, 加藤英明, 加藤英明, 名倉淑子, 岩田想, 伊藤耕一, et al. 小胞体Ca²⁺恒常性に関わるイオンチャネルのX線結晶構造解析. 日本生化学会大会(Web). 2015. 88th
KONNO Masae, INOUE Keiichi, INOUE Keiichi, KATO Hideaki, NUREKI Osamu, KANDORI Hideki. Engineering K+ pumping rhodopsin from KR2. 生物物理(Web). 2015. 55. Supplement 1-2

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Patents (3)：

Books (17)：

新しいチャネルロドプシンと光遺伝学
科学評論社糖尿病・内分泌代謝科 2023
Cryo-EM analysis of dynamic G-protein activation process by neurotensin receptor 1
2022
Structural biology of the non-class A GPCRs
2022
Structural biology of the class A GPCRs (2)
2022
Structural biology of the class A GPCRs (1)
2022

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Lectures and oral presentations (58)：

Structural diversity of channelrhodopsins
(20th International Conference on Retinal Proteins 2024)
Dynamics of the GDP/GTP Exchange Reaction Catalyzed by GPCRs
(The 97th Annual Meeting of the Japanese Biochemical Society 2024)
Structural basis for color tuning and ion selectivity in potassium-selective channelrhodopsins
(Quantum Innovation 2024 2024)
The molecular basis of the high K+ ion selectivity in light-gated ion channels.
("NIPS Workshop: Frontiers and Future Directions in Membrane Protein Functional Dynamics for Understanding Physiological Functions" 2024)
Structural and functional analysis of light-gated ion channels assisted by rapid DNA synthesis services
(IUPAB2024 2024)

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Education (3)：

2011 - 2014 The University of Tokyo School of Science Department of Biophysics and Biochemistry
2009 - 2011 The University of Tokyo School of Science Department of Biophysics and Biochemistry
2005 - 2009 The University of Tokyo Faculty of Science

Professional career (1)：

Work history (10)：

2024/02 - 現在 The University of Tokyo Research Center for Advanced Science and Technology Professor
2024/02 - 現在 The University of Tokyo Graduate School of Science Department of Biological Sciences Professor(Adjunct)
2024/02 - 現在 The University of Tokyo The Graduate School of Engineering Department of Advanced Interdisciplinary Studies Professor(Adjunct)
2024/02 - 現在 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences Professor(Adjunct)
2020/04 - 2024/01 The University of Tokyo Graduate School of Science Department of Biological Sciences associate professor(Adjunct)

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Committee career (6)：

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Awards (15)：

2024/06 - International Union for Pure and Applied Biophysics (IUPAB) IUPAB Young Investigator Prize
2024/04 - Nakatani Foundation Kobe Prize, Young Investigator Awards
2020/12 - Shimadzu Foundation Shimadzu Young Researcher Award
2020/09 - The Frontier Salon Foundation 10th Frontier Salon Nagase Prize, Special Prize
2020/04 - The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists’ Award

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Association Membership(s) (1)：

The Biophysical Society of Japan

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