Research theme for competitive and other funds (5):
2024 - 2028 Elucidating the role of SARM1 in senescence and aging related diseases
2024 - 2025 2023 Kindai University Research Enchancement Grant
2023 - 2025 Elucidating the role of SARM1 under inflammation
2023 - 2024 Suzuken Memorial Foundation Research grant (2023)
2017 - 2017 Analysis of the effect of inseparable association of AIM with IgM on obesity-related diseases
Papers (12):
Ryoichi Sugisawa, Katharine A. Shanahan, Gavin Davis, Gavin Davey, Andrew G. Bowie. SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms. iScience. 2024. 109940-109940
Katharine A. Shanahan, Gavin M. Davis, Ciara G. Doran, Ryoichi Sugisawa, Gavin P. Davey, Andrew G. Bowie. SARM1 regulates NAD+-linked metabolism and select immune genes in macrophages. Journal of Biological Chemistry. 2024
Masaki Watanabe, Ryo Ando, Ryoichi Sugisawa, Nobuya Sasaki, Satomi Iwai. A novel in vivo model of ureteral fibrosis induced by calcium oxalate beads in C57BL/6J mice. Urolithiasis. 2023. 51. 1. 119
Claudia Feriotti, Joana Sá-Pessoa, Ricardo Calderón-González, Lili Gu, Brenda Morris, Ryoichi Sugisawa, Jose L. Insua, Michael Carty, Amy Dumigan, Rebecca J. Ingram, et al. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity. Cell Reports. 2022. 40. 6. 111167-111167
Claudia Feriotti, Joana Sa-Pessoa, Ricardo Calderón-González, Lili Gu, Brenda Morris, Ryoichi Sugisawa, Jose L. Insua, Michael Carty, Amy Dumigan, Rebecca J. Ingram, et al. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity. bioRxiv. 2021
Ciara G. Doran, Ryoichi Sugisawa, Michael Carty, Fiona Roche, Claire Fergus, Karsten Hokamp, Vincent P. Kelly, Andrew G Bowie. Next generation SARM1 knockout and epitope tagged CRISPR-Cas9-generated isogenic mice reveal that SARM1 does not participate in regulating nuclear transcription, despite confirmation of protein expression in macrophages. bioRxiv. 2021
Ryoichi Sugisawa, Ciara G Doran, Andrew G Bowie. Generation and initial characterization of a SARM epitope-tagged mouse. European Journal of Immunology. 2021. 51. (Suppl. 1). 207-207
SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
SARM1 regulates pro-inflammatory cytokine expression by NADase-dependent and -independent mechanism
(The 166th meeting of the Japanese Society of Veterinary Science 2023)
SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
(Irish Society for Immunology Annual Meeting 2022 2022)
Clarifying the role of human SARM1, and its NADase activity, in monocytes
(Host Pathogen Communication 2021 2021)
Generation and initial characterization of a SARM epitope-tagged mouse
(the Virtual 6th European Congress of Immunology - ECI 2021 2021)
2013 - 2017 The University of Tokyo Faculty of Medicine Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine
2007 - 2013 Nippon Veterinary and Life science University Faculty of Veterinary Science School of Veterinary Medicine
Professional career (1):
Ph.D. (The University of Tokyo)
Work history (3):
2023/04 - 現在 Kindai University, Faculty of Medicine Dept. of Biochemistry Assistant Professor
2017/12 - 2023/03 Trinity College Dublin School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute Research Fellow
2017/04 - 2017/11 The University of Tokyo, Faculty of Medicine Project Assistant Professor
Awards (4):
2021/09 - EFIS (European Federation of Immunological Societies) Waived Registration Grant (for Virtual 6th European Congress of Immunology - ECI 2021)
2019/09 - The Japanese Society of Veterinary Science Veterinary Science Young Investigator Awards
2018/11 - HOST-PATHOGEN COMMUNICATION TRAVEL AWARD
2016/09 - The 159th meeting of the Japanese Society of Veterinary Science Young Investigator Award (Physiology and Biochemistry Subcommittee of The Japanese Society of Veterinary Science)
Association Membership(s) (4):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF VETERINARY SCIENCE
, Irish Society for Immunology
, International Cytokine & Interferon Society