Rchr
J-GLOBAL ID:201701002711925515   Update date: May. 10, 2024

Sugisawa Ryoichi

スギサワ リョウイチ | Sugisawa Ryoichi
Affiliation and department:
Job title: Assistant Professor
Research field  (4): Pathobiochemistry ,  Immunology ,  Medical biochemistry ,  Veterinary medicine
Research keywords  (18): Macrophage ,  Innate Immunity ,  Inflammation ,  Immunometabolism ,  TLR ,  Inflammasome ,  NADase ,  Auto immune disease ,  Fatty liver ,  Obesity ,  Kidney disease ,  Neuronal disorder ,  Axon degeneration ,  Transgenic mice models ,  Cat / Felis catus ,  AIM / CD5L ,  SARM1 ,  NAD
Research theme for competitive and other funds  (5):
  • 2024 - 2028 Elucidating the role of SARM1 in senescence and aging related diseases
  • 2024 - 2025 2023 Kindai University Research Enchancement Grant
  • 2023 - 2025 Elucidating the role of SARM1 under inflammation
  • 2023 - 2024 Suzuken Memorial Foundation Research grant (2023)
  • 2017 - 2017 Analysis of the effect of inseparable association of AIM with IgM on obesity-related diseases
Papers (12):
  • Ryoichi Sugisawa, Katharine A. Shanahan, Gavin Davis, Gavin Davey, Andrew G. Bowie. SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms. iScience. 2024. 109940-109940
  • Suman Dash, Takeshi Ueda, Akiyoshi Komuro, Masahiko Honda, Ryoichi Sugisawa, Hitoshi Okada. Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metabolism interference in pancreatic cancer. Cell Death & Disease. 2024
  • Katharine A. Shanahan, Gavin M. Davis, Ciara G. Doran, Ryoichi Sugisawa, Gavin P. Davey, Andrew G. Bowie. SARM1 regulates NAD+-linked metabolism and select immune genes in macrophages. Journal of Biological Chemistry. 2024
  • Masaki Watanabe, Ryo Ando, Ryoichi Sugisawa, Nobuya Sasaki, Satomi Iwai. A novel in vivo model of ureteral fibrosis induced by calcium oxalate beads in C57BL/6J mice. Urolithiasis. 2023. 51. 1. 119
  • Claudia Feriotti, Joana Sá-Pessoa, Ricardo Calderón-González, Lili Gu, Brenda Morris, Ryoichi Sugisawa, Jose L. Insua, Michael Carty, Amy Dumigan, Rebecca J. Ingram, et al. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity. Cell Reports. 2022. 40. 6. 111167-111167
more...
MISC (4):
Lectures and oral presentations  (18):
  • SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
    (The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
  • SARM1 regulates pro-inflammatory cytokine expression by NADase-dependent and -independent mechanism
    (The 166th meeting of the Japanese Society of Veterinary Science 2023)
  • SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
    (Irish Society for Immunology Annual Meeting 2022 2022)
  • Clarifying the role of human SARM1, and its NADase activity, in monocytes
    (Host Pathogen Communication 2021 2021)
  • Generation and initial characterization of a SARM epitope-tagged mouse
    (the Virtual 6th European Congress of Immunology - ECI 2021 2021)
more...
Education (2):
  • 2013 - 2017 The University of Tokyo Faculty of Medicine Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine
  • 2007 - 2013 Nippon Veterinary and Life science University Faculty of Veterinary Science School of Veterinary Medicine
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (3):
  • 2023/04 - 現在 Kindai University, Faculty of Medicine Dept. of Biochemistry Assistant Professor
  • 2017/12 - 2023/03 Trinity College Dublin School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute Research Fellow
  • 2017/04 - 2017/11 The University of Tokyo, Faculty of Medicine Project Assistant Professor
Awards (4):
  • 2021/09 - EFIS (European Federation of Immunological Societies) Waived Registration Grant (for Virtual 6th European Congress of Immunology - ECI 2021)
  • 2019/09 - The Japanese Society of Veterinary Science Veterinary Science Young Investigator Awards
  • 2018/11 - HOST-PATHOGEN COMMUNICATION TRAVEL AWARD
  • 2016/09 - The 159th meeting of the Japanese Society of Veterinary Science Young Investigator Award (Physiology and Biochemistry Subcommittee of The Japanese Society of Veterinary Science)
Association Membership(s) (4):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF VETERINARY SCIENCE ,  Irish Society for Immunology ,  International Cytokine & Interferon Society
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