Rchr
J-GLOBAL ID:201701003305227277   Update date: Apr. 30, 2024

IMAMURA HIROSHI

イマムラ ヒロシ | IMAMURA HIROSHI
Research field  (4): Other ,  Biophysics ,  Pharmaceuticals - analytical and physicochemistry ,  Basic physical chemistry
Research keywords  (4): Biophysics ,  Protein science ,  Design ,  Physical chemistry
Research theme for competitive and other funds  (7):
  • 2022 - 2026 Study on the origin of sustained drug releasability of polymeric nanomicelles based on clarifying the interaction potential surface
  • 2021 - 2024 Studies for early prediction of physical degradation of therapeutic proteins
  • 2019 - 2020 Solution structure of artificial proteins analyzed by a small angle scattering
  • 2017 - 2018 Development of an intuitive molecular modeling system using small angle scattering
  • 2013 - 2014 Design and characterization of pressure-responsive artificial proteins/peptides
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Papers (53):
  • H. Imamura, M. Kamimura, M. Kawase. A student experiment to realize protein charge via ion-exchange chromatography of lysozyme and Nakamura effect. 2024. 102. 2. 67-75
  • Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki, Yuki Fujii, Shaymaa Mohamed Mohamed Badawy, Ken Morishima, Aya Okuda, Rintaro Inoue, Masaaki Sugiyama, Eri Chatani. Mechanistic modeling of amyloid oligomer and protofibril formation in bovine insulin. Journal of Molecular Biology. 2024. 168461-168461
  • Haruka Hiroe, Masashi Kawamoto, Hiroshi Imamura, Tomomi Koshiyama. Energy transfer on cytoskeleton of red blood cell ghosts and their efficiency control by KCl concentration-induced cell shrinkage. Chemistry - A European Journal. 2024
  • Noa Nakata, Ryuichi Okamoto, Tomonari Sumi, Kenichiro Koga, Takeshi Morita, Hiroshi Imamura. Molecular mechanism of the common and opposing co-solvent effects of fluorinated alcohol and urea on a coiled coil protein. Protein Science. 2023. 32. 10. e4763
  • Xinjia Wang, Seiji Hatta, Daisuke Matsui, Hiroshi Imamura, Mamoru Wakayama. Expression and characterization of C-terminal truncated mutants of γ-glutamyltranspeptidase II (PaGGTII) from Pseudomonas aeruginosa PAO1. Protein Expression and Purification. 2023. 106321-106321
more...
MISC (26):
  • Hiroshi Imamura. 蛋白質の変性を熱力学的にみると. 2024
  • Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki, Yuki Fujii, Shaymaa Mohamed, Mohamed Badawy, Ken Morishima, Aya Okuda, Rintaro Inoue, Masaaki Sugiyama, et al. Mechanistic modeling of amyloid oligomer and protofibril formation. bioRxiv. 2023
  • Hiroshi Imamura. (寄稿) 「弱いロボット(岡田美智男著)」の紹介. 滋賀県大学図書館のおすすめ本. 2023. 2
  • Tomonari Sumi, Hiroshi Imamura. Are proteins stabilized by hydrophobic effects? (reproduced article). Agricultural Biotechnology. 2023. 7. 4. 372-377
  • Tomonari Sumi, Hiroshi Imamura. Are proteins stabilized by hydrophobic effects?. The CELL. 2023. 55. 2. 104-107
more...
Books (5):
  • タンパク質の構造解析手法とIn silicoスクリーニングへの応用事例
    2023 ISBN:9784861049712
  • Analytical methods for biopharmaceuticals
    2022 ISBN:4840754608
  • Therapeutic Antibodies: Methods and Protocols
    Humana, New York 2021 ISBN:9781071614495
  • Protein Solubility and Amorphous Aggregation: From Academic Research to Applications in Drug Discovery and Bioindustry
    CMC Publishing Co.,Ltd. 2019 ISBN:9784781313979
  • 極限環境の生体分子-過酷な環境下での機能を科学する-
    化学同人 2014 ISBN:9784759813777
Lectures and oral presentations  (167):
  • Proteins being smaller by denaturation: SEC-SAXS analysis of denatured antibodies
    (Extended / advanced use of SAXS method in materials science and biology 2024)
  • 抗体の不思議な構造変化:酸性溶液中では天然構造よりも小さくコンパクトな球状構造になる
    (The 2nd Annual Meeting of the Antibody Society of Japan 2023)
  • バイオ医薬品タンパク質の変性と凝集問題
    (23-1高分子計算機科学研究会-高分子の劣化・DNAの損傷・タンパク質の変性:シミュレーションと実践の連携を探求して 2023)
  • Mechanistic modeling of amyloid oligomer and protofibril formation of bovine insulin
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
  • Myoglobin evolution in Paleozoic era
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
more...
Works (8):
  • Phone2SAS program: computing small-angle scattering from 3D scanned objects
    Hiroshi Imamura 2023 - 現在
  • (小角X線散乱データ) SASDQA9 - Immunoglobulin G1 (pH 2, 0.2 M NaCl), SEC-SAXS data
    H. Imamura, A. Ooishi, S. Honda 2023 - 現在
  • (円偏光二色性スペクトルデータ) CD0006424000: Immunoglobulin G1, CD0006424001: Immunoglobulin G1 (pH 2, 3 Hours), CD0006424002: Immunoglobulin G1 (pH 2, 12 Days)
    H. Imamura, A. Ooishi, S. Honda 2023 -
  • (小角X線散乱データ) SASDQ99 - Immunoglobulin G1 (pH 2, 0 M NaCl), SEC-SAXS data
    H. Imamura, A. Ooishi, S. Honda 2023 -
  • (小角X線散乱データ) SASDNL7 - Guanine-rich DNA derived from the promoter region of c-MYC gene (MYC22-G14T/G23T) with 18-crown-6
    K. Miyauchi, H. Imamura, Y. Yamaoki, M. Kato 2022 -
more...
Education (4):
  • 2006 - 2010 Ritsumeikan University Graduate School of Science and Engineering Science and Engineering
  • 2007 - 2008 ポーランド高圧力物理学研究所(Wojciech Dzwolak 教授) (短期留学)
  • 2004 - 2006 Ritsumeikan University Graduate School of Science and Engineering
  • 2001 - 2004 Ritsumeikan University College of Science and Engineering Department of Applied Chemistry
Professional career (1):
  • Ph.D. (Ritsumeikan University)
Work history (10):
  • 2022/04 - 現在 Nagahama Institute of Bio-Science and Technology Graduate School of Biosciences Assistant Professor
  • 2017/08 - 2022/03 National Institute of Advanced Industrial Science and Technology, Biomedical Research Institute, Research Fellowship (Collaborative Researcher)
  • 2017/04 - 2022/03 Ritsumeikan University, College of Life Science, Assistant professor
  • 2018/04 - 2018/09 University of Copenhagen, Niels Bohr Institute, Guest Researcher
  • 2014/04/01 - 2017/03/31 National Institute of Advanced Industrial Science and Technology Biomedical Research Institut Postdoctoral Fellow
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Awards (6):
  • 2021/05 - Ritsumeikan University Challenging Practice 2020
  • 2020/07 - Protein Science Society of Japan Young Scientist Award
  • 2020/03 - 立命館大学生命科学部 若手教員奨励賞
  • 2004/03 - 立命館大学父母教育後援会 理工学部長優秀賞
  • 2003 - Ritsumeikan University Saionji Memorial Scholarship Academically Outstanding Students Category
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Association Membership(s) (4):
The Antibody Society of Japan ,  The Japan Society of Calorimetry and Thermal Analysis コンテンツへスキップ ,  Protein science society of Japan ,  The Biophysical Society of Japan
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