Research theme for competitive and other funds (7):
2023 - 2026 新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割
2023 - 2026 Elucidation of substrate recognition mechanism of SLC19A3 to establish the molecular basis for medical applications
2020 - 2023 新規ポリアミントランスポーターの機能及び生理的役割の解明
2020 - 2023 Elucidation of molecular mechanism that triggers onset of gout from hyperuricemia
2018 - 2020 Relationship between novel thiamine pool mechanism and proliferative capacity in cancer cells
2018 - 2020 Elucidation of a novel pool mechanism of B vitamins through lysosome accumulation
2016 - 2018 Molecular mechanism of estrogen supply pathway in hormone-sensitive breast cancer
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Papers (32):
SLC35G1 is a highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption. eLife. 2024
Akira Hosooka, Tomoya Yasujima, Ayano Murata, Takahiro Yamashiro, Hiroaki Yuasa. Identification of human-specific amino acid residues governing atenolol transport via organic cation transporter 2. Biochemical Pharmacology. 2024. 116514-116514
Shogo Akino, Tomoya Yasujima, Rei Shibutani, Takahiro Yamashiro, Hiroaki Yuasa. Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine. Drug Metabolism and Disposition. 2023. 52. 1. 19-25
Shogo Akino, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa. Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter. Life Science Alliance. 2023. 6. 2. e202201629-e202201629
Kohei Miyake, Tomoya Yasujima, Syunsuke Takahashi, Takahiro Yamashiro, Hiroaki Yuasa. Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A3. Journal of Biological Chemistry. 2022. 298. 8. 102161-102161