Research field (2):
Animals: biochemistry, physiology, behavioral science
, Biophysics
Research theme for competitive and other funds (5):
2022 - 2025 AQP4-dependent ATP/Adenosine releaser from astrocyte following neuronal activities
2021 - 2025 Construction of further biased optical control tools manipulating GPCR signalings
2017 - 2020 Investigation of molecular mechanisms underlying environment-dependent regulation of ion permeation through mammalian potassium channels.
2013 - 2015 Analyses of molecular characteristics in mammalian melanopsins to receive ambient light signals.
2012 - 2014 Functional expression of mammalian ion channels and analysis of the molecular mechanisms
Papers (39):
Kentaro Fukuta, Dai-Ichiro Kato, Juri Maeda, Atsuhiro Tsuruta, Hirobumi Suzuki, Yukio Nagano, Hisao Tsukamoto, Kazuki Niwa, Makoto Terauchi, Atsushi Toyoda, et al. Genome assembly of Genji firefly (Nipponoluciola cruciata) reveals novel luciferase-like luminescent proteins without peroxisome targeting signal. DNA research : an international journal for rapid publication of reports on genes and genomes. 2024. 31. 2
Hisao Tsukamoto, Yoshihiro Kubo. A self-inactivating invertebrate opsin optically drives biased signaling toward Gβγ-dependent ion channel modulation. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 21. e2301269120
Hisao Tsukamoto, Yuji Furutani. Optogenetic Modulation of Ion Channels by Photoreceptive Proteins. Advances in experimental medicine and biology. 2021. 1293. 73-88
Nagata T, Koyanagi M, Tsukamoto H, Mutt E, Schertler GFX, Deupi X, Terakita A. The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation. Communications biology. 2019. 2. 180-180