Rchr
J-GLOBAL ID:201701003745982468   Update date: Jun. 01, 2024

Tsukamoto Hisao

Tsukamoto Hisao
Affiliation and department:
Research field  (2): Animals: biochemistry, physiology, behavioral science ,  Biophysics
Research theme for competitive and other funds  (5):
  • 2022 - 2025 AQP4-dependent ATP/Adenosine releaser from astrocyte following neuronal activities
  • 2021 - 2025 Construction of further biased optical control tools manipulating GPCR signalings
  • 2017 - 2020 Investigation of molecular mechanisms underlying environment-dependent regulation of ion permeation through mammalian potassium channels.
  • 2013 - 2015 Analyses of molecular characteristics in mammalian melanopsins to receive ambient light signals.
  • 2012 - 2014 Functional expression of mammalian ion channels and analysis of the molecular mechanisms
Papers (39):
  • Kentaro Fukuta, Dai-Ichiro Kato, Juri Maeda, Atsuhiro Tsuruta, Hirobumi Suzuki, Yukio Nagano, Hisao Tsukamoto, Kazuki Niwa, Makoto Terauchi, Atsushi Toyoda, et al. Genome assembly of Genji firefly (Nipponoluciola cruciata) reveals novel luciferase-like luminescent proteins without peroxisome targeting signal. DNA research : an international journal for rapid publication of reports on genes and genomes. 2024. 31. 2
  • Hisao Tsukamoto, Yoshihiro Kubo. A self-inactivating invertebrate opsin optically drives biased signaling toward Gβγ-dependent ion channel modulation. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 21. e2301269120
  • Hisao Tsukamoto, Yuji Furutani. Optogenetic Modulation of Ion Channels by Photoreceptive Proteins. Advances in experimental medicine and biology. 2021. 1293. 73-88
  • Hisao Tsukamoto, Yoshinori Shichida. Session 2SFA-the symposium "Elucidation of biological functions by optical control" on BSJ2019 at Miyazaki, Japan. Biophysical reviews. 2020
  • Nagata T, Koyanagi M, Tsukamoto H, Mutt E, Schertler GFX, Deupi X, Terakita A. The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation. Communications biology. 2019. 2. 180-180
more...
MISC (15):
  • Hisao TSUKAMOTO. Development of Gβγ-Biased Optical Control Tools Based on an Invertebrate Opsin. Seibutsu Butsuri. 2024. 64. 1. 32-34
  • Hisao Tsukamoto. Development of a “finely-biased” optical control tool using a self- inactivating photosensitive GPCR. SEIKAGAKU. 2024. 96. 1. 70-74
  • Hisao TSUKAMOTO. Functional characteristics of animal opsins as optical control tools. Hikaku seiri seikagaku(Comparative Physiology and Biochemistry). 2022. 39. 2. 84-91
  • Hisao Tsukamoto. Optical control of cellular signaling pathways using animal opsins. Biomedical Imaging and Sensing Conference 2021. 2021. 119250E
  • 塚本 寿夫. 【書評】細胞のマルチスケールメカノバイオロジー. 生物物理. 2017. 57. 5. 278-278
more...
Books (3):
  • 光と生命の事典
    朝倉書店 2016
  • The evolution of visual and non-visual pigments
    Springer 2014
  • 動物の多様な生き方1 見える光,見えない光
    共立出版 2009
Lectures and oral presentations  (22):
  • Optical modulation of ion channel activity by opsin, light-sensitive GPCR
    (Ion Channel Modulation Symposium - Japan 2024 2024)
  • Molecular characteristics of an invertebrate Gi/o-coupled and visible light-sensitive opsin
    (2023)
  • Development of a Gs-coupled optogenetic tool that can be turned on and off by visible light
    (2023)
  • Analysis of invertebrate-type opsin-mediated G protein activation and downstream signaling kinetics using luminescent biosensors
    (2023)
  • Biochemical and computational analyses of interactions between mammalian melanopsins and a specific antagonist
    (2023)
more...
Professional career (1):
  • PhD (Kyoto University)
Work history (13):
  • 2022/04 - 現在 Kobe University
  • 2020/06 - 現在 Kobe University Graduate School of Science Division of Biology
  • 2017/10 - 2021/03 JSTさきがけ 研究者(研究期間は2021年9月まで)
  • 2014/04 - 2020/05 The Graduate University for Advanced Studies School of Physical Sciences
  • 2014/02 - 2020/05 Institute for Molecular Science
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