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J-GLOBAL ID：201701004997744434   Update date: Jun. 07, 2024

Hoshino Tomonori

ホシノ トモノリ | Hoshino Tomonori
Affiliation and department：
Massachusetts General Hospital, Harvard Medical School Department of Radiology

About Massachusetts General Hospital, Harvard Medical School Department of Radiology


Research field  (6)： Cardiology ,  Pathobiochemistry ,  Neuropathology ,  Molecular biology ,  Neurology ,  Neuroscience - general
Research keywords  (21)： RNA-seq ,  Dementia ,  Alzheimer's disease ,  Circadian rhythm ,  Brain calcification ,  Vascular calcification ,  Tissue Clearing (Brain) ,  Light Sheet Microscopy ,  μCT ,  MRI ,  Transcriptome analysis ,  Aging ,  Ectopic calcification ,  multi-tissue interaction ,  vascular dysfunction ,  Ferroptosis ,  Hypoxia ,  Cell death ,  Neurodegenerative disease ,  Oxidative stress ,  Proteasome
Research theme for competitive and other funds  (9)：
  • 2022 - 2028 先端モデル動物支援プラットフォーム (生理機能解析支援) 2021年度 第3回
  • 2022 - 2028 Advanced Animal Model Support
  • 2022 - 2028 先端モデル動物支援プラットフォーム (病理形態解析支援) 2021年 第1回
  • 2022 - 2028 Advanced Bioimaging Support
  • 2022 - 2028 Platform for Advanced Genome Science
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Papers (7)：
  • Tomonori Hoshino, Hajime Takase, Gen Hamanaka, Shintaro Kimura, Norito Fukuda, Emiri T Mandeville, Josephine Lok, Eng H Lo, Ken Arai. Transcriptomic Changes in Oligodendrocyte Lineage Cells During the Juvenile to Adult Transition in the Mouse Corpus Callosum. 2024
  • Tomonori Hoshino, Davood Kharaghani, Shohei Kohno. Extracellular Histones Promote Calcium Phosphate-Dependent Calcification in Mouse Vascular Smooth Muscle Cells. The Journal of Biochemistry. 2024
  • Hajime Takase, Gen Hamanaka, Tomonori Hoshino, Ryo Ohtomo, Shuzhen Guo, Emiri T. Mandeville, Eng H. Lo, Ken Arai. Transcriptomic Profiling Reveals Neuroinflammation in the Corpus Callosum of a Transgenic Mouse Model of Alzheimer’s Disease. Journal of Alzheimer's Disease. 2024. 97. 3. 1421-1433
  • Davood Kharaghani, Shohei Kohno, Tomoko Minamizaki, Tomonori Hoshino, Yuji Yoshiko. 2,3-Diphospho-D-glyceric acid inhibits calciprotein particle growth and calcification in MOVAS cells but not in MC3T3-E1 cells. Colloids and Interface Science Communications. 2022. 50
  • Faisal Ahmed, Tomoko Minamizaki, Shohei Kohno, Jane E. Aubin, Davood Kharaghani, Tomonori Hoshino, Yuji Yoshiko. Large Scale Analysis of Osteocyte Lacunae in Klotho Hypomorphic Mice Using High-Resolution Micro-Computed Tomography. SSRN Electronic Journal. 2022
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MISC (9)：
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Books (3)：
  • Cell Death Mechanism of Neurodegenerative Diseases
    Journal of Clinical and Experimental Medicine (IGAKU NO AYUMI) 285(5) 2022 ISBN:9784006028305
  • Cell Death (DOJIN BIOSCIENCE SERIES)
    Kagaku-Dojin Publishing Company,INC 2019 ISBN:9784759817317
  • タンパク質分解障害
    メディカルドゥ 脳内環境辞典 2017 ISBN:9784944157648
Education (3)：
  • 2015 - 2019 Kyoto University Graduate School of Medicine Doctoral Program in Medicine
  • 2013 - 2015 京都大学大学院 医学研究科 医科学専攻 修士課程
  • 2009 - 2013 Kitasato University School of Allied Health Sciences Department of Medical Laboratory Sciences
Professional career (1)：
  • Ph.D. (Kyoto University)
Work history (4)：
  • 2023/05 - 現在 ハーバード大学マサチューセッツ総合病院 ポスドク
  • 2020/06 - 2023/03 Graduate School of Biomedical and Health Sciences, Hiroshima University Department of Calcified Tissue Biology Assistant Professor
  • 2019/04 - 2020/05 Kyoto University Hospital Dept. Neurology, Drug Screening Incubation Laboratory Researcher
  • 2017/04 - 2019/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (DC2)
Awards (2)：
  • 2019/07 - NEURO2019 Domestic Travel Award
  • 2018/08 - Free Radical School Society for Free Radical Research JAPAN Best Poster Award
Association Membership(s) (8)：
The Japanese Society for Cell Death Research ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  The Japanese Society for Bone and Mineral Research ,  Japanese Association for Oral Biology ,  JAPANESE SOCIETY OF NEUROLOGY ,  THE JAPANESE SOCIETY OF NEUROPATHOLOGY
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