Nakajima Shotaro

ナカジマショウタロウ | Nakajima Shotaro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.gi-t-surg.com

Research field (1)： Tumor biology

Research keywords (3)： molecular biology , Oncoimmunology , Immunology

Research theme for competitive and other funds (19)：

2024 - 2027 What is the best choice for the effective combinational treatment with immune checkpoint inhibitor
2023 - 2026 STING経路を標的としたHER2陽性胃癌の新規治療戦略
2022 - 2025 放射線とNivo併用におけるImmunogenic cell deathの検証
2022 - 2025 The effect of T-DXd on the anti-tumor immune response in HER2-positive gastric cancer
2022 - 2025 The role of the cGAS-STING pathway for regulations of tumor-microenvironment by immunoradiotherapy in esophageal squamous cell carcinoma

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Papers (64)：

Ryo Kanoda, Shotaro Nakajima, Satoshi Fukai, Motonobu Saito, Katsuharu Saito, Hiroya Suzuki, Tomohiro Kikuchi, Azuma Nirei, Hirokazu Okayama, Kosaku Mimura, et al. High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8+ T cells in dMMR/MSI-H gastric cancer. Scientific reports. 2024. 14. 1. 20859-20859
Akira Matsuishi, Shotaro Nakajima, Motonobu Saito, Katsuharu Saito, Satoshi Fukai, Hideaki Tsumuraya, Ryo Kanoda, Tomohiro Kikuchi, Azuma Nirei, Akinao Kaneta, et al. The impact of CLDN18.2 expression on effector cells mediating antibody-dependent cellular cytotoxicity in gastric cancer. Scientific reports. 2024. 14. 1. 17916-17916
Hideaki Tsumuraya, Kosaku Mimura, Shotaro Nakajima, Hiroyuki Hanayama, Akira Matsuishi, Hirokazu Okayama, Satoshi Fukai, Misato Ito, Mai Ashizawa, Shun Chida, et al. Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer. Anticancer research. 2024. 44. 7. 2933-2941
Shuhei Yamashita, Kento Miura, Anna Matsuura, Norimasa Yamasaki, Naoto Uda, Sawako Ogata, Naohisa Hosomi, Shotaro Nakajima, Noriko Kitamura, Minoru Gotoh, et al. α7 nicotinic acetylcholine receptor agonist attenuates allergen-induced immediate nasal response in murine model of allergic rhinitis. The Journal of veterinary medical science. 2024
Mei Sakuma, Masanori Katagata, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Takahiro Sato, Satoshi Fukai, Hideaki Tsumuraya, Hisashi, Onozawa, Wataru Sakamoto, et al. TIM-3 expression on dendritic cells in colorectal cancer. Cancers. 2024. 16. 10

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MISC (7)：

Shotaro Nakajima, Satoshi Fukai, Akinao Kaneta, Hideaki Tsumuraya, Akira Matsuishi, Hirokazu Okayama, Motonobu Saito, Kosaku Mimura, Wataru Sakamoto, Zenichiro Saze, et al. [Regulation of the Tumor Microenvironment through HER2 Signaling-Insights from Gastric Cancer Cases with Heterogeneous HER2 Overexpression]. Gan to kagaku ryoho. Cancer & chemotherapy. 2024. 51. 9. 903-905
中嶋正太郎, 河野浩二. 食道癌の腫瘍免疫微小環境. 日本臨牀食道癌2024ー基礎・臨床の最新動向ー. 2024. 82. 3. 90-95
Shotaro Nakajima, Kosaku Mimura, Akinao Kaneta, Masanori Katagata, Hirokazu Okayama, Motonobu Saito, Zenichiro Saze, Hiroyuki Hanayama, Takeshi Tada, Tomoyuki Momma, et al. [Remodeling of the Tumor Microenvironment by Radiotherapy through the cGAS-STING Pathway in Esophageal Squamous Cell Carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy. 2023. 50. 10. 1099-1101
Shotaro Nakajima, Akinao Kaneta, Koji Kono. [The Potential of a Novel Therapeutic Strategy for Colorectal Cancer Targeting the cGAS-STING Pathway]. Gan to kagaku ryoho. Cancer & chemotherapy. 2023. 50. 9. 950-954
Akinao Kaneta, Shotaro Nakajima, Kosaku Mimura, Koji Kono. [Expression of the cGAS-STING Pathway in dMMR/MSI-H in Colorectal Cancer]. Gan to kagaku ryoho. Cancer & chemotherapy. 2022. 49. 10. 1130-1132

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Books (3)：

分子細胞免疫学原著第10版 : アバス-リックマン-ピレ
エルゼビア・ジャパン 2023 ISBN:9784860346768
Basic Immunology: Functions and Disorders of the immune System Sixth Edition
2020
Cellular and molecular immunology
Elsevier 2018

Lectures and oral presentations (20)：

腫瘍細胞内cGAS-STING 経路がFP 療法による食道扁平上皮癌微小環境の変化に及ぼす影響
(第37回日本バイオセラピィ学会学術集会総会 2024)
食道扁平上皮癌において腫瘍細胞内cGAS-STING経路が術前化学療法によるCD8+ T細胞浸潤に及ぼす影響の解析
(第45回癌免疫外科研究会 2024)
HER2不均一発現を呈する胃癌症例から検討するHER2シグナルを介した腫瘍免疫微小環境の制御
(第36回日本バイオセラピィ学会学術集会総会 2023)
The effect of IL-34 expression triggered by neoadjuvant chemotherapy on the tumor-microenvironment and clinical outcomes in patients with esophageal squamous cell carcinoma
(The 3rd International Congress of the Asian Oncology Society 2023)
The effect of cGAS-STING pathway on the infiltration of CD8+ T cells and clinical outcomes in pMMR/MSS colorectal cancer
(The 82nd annual meeting of the Japanese cancer association 2023)

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Education (3)：

2010 - 2013 University of Yamanashi Department of Education Interdisciplinary Graduate School of Medicine and Engineering
2008 - 2010 University of Yamanashi Department of Education Interdisciplinary Graduate School of Medicine and Engineering
2004 - 2008 University of Yamanashi

Professional career (1)：

Ph.D. (Medical Science)

Work history (9)：

2022/01 - 現在 Fukushima Medical University Department of Multidisciplinary Treatment of Cancer and Regional Medical Support Associate Professor
2017/01 - 2023/03 エルゼビアジャパン eReview コミッティメンバー免疫学
2020/12 - 2021/12 Fukushima Medical University Department of Obesity and Inflammation Research/Department of Gastrointestinal Tract Surgery Lecturer
2020/02 - 2020/11 Fukushima Medical University Dept. Medical Electrophysiology/Dept. Gastrointestinal Tract Surgery Lecturer
2019/06 - 2020/01 Fukushima Medical University Dept. Progressive DOHaD Research/Dept. of Gastrointestinal Tract Surgery Lecturer

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Awards (2)：

2023/12 - 日本バイオセラピィ学会第36回日本バイオセラピィ学会学術集会総会奨励賞 HER2不均一発現を呈する胃癌症例から検討するHER2シグナルを介した腫瘍免疫微小環境の制御
2023/06 - 癌免疫外科研究会第44回癌免疫外科研究会奨励賞照射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化

Association Membership(s) (3)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本バイオセラピィ学会 , THE JAPANESE CANCER ASSOCIATION

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