Rchr
J-GLOBAL ID:201701006536115586   Update date: Jun. 14, 2024

Shimada Atsuhiro

Shimada Atsuhiro
Affiliation and department:
Job title: 助教
Research field  (1): Structural biochemistry
Research theme for competitive and other funds  (5):
  • 2022 - 2024 The structure determination of cytochrome c oxidase by pump-probe X-ray crystallography using rapid mixing injector.
  • 2018 - 2022 Fine structures of reaction inter-mediates of bovine cytochrome c oxidase
  • 2018 - 2021 XFEL時分割構造解析によるチトクロム酸化酵素の反応機構の解明
  • 2015 - 2018 X線自由電子レーザーを用いた、常温での高分解能無損傷X線結晶構造解析方法の開発
  • 2011 - 2012 エラーフリー PCR を目指した DNA ミスマッチ修復系のシステム生物学的解析
Papers (28):
  • Atsuhiro Shimada, Jumpei Baba, Shuhei Nagao, Kyoko Shinzawa-Itoh, Eiki Yamashita, Kazumasa Muramoto, Tomitake Tsukihara, Shinya Yoshikawa. Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons. The Journal of biological chemistry. 2023. 105277-105277
  • Daiki Sugihara, Fuka Ono, Motoki Sugino, Hiromi Suzuki, Noriko Endo, Atsuhiro Shimada, Akio Ebihara. Production of recombinant His-tagged triple-FLAG peptide in Brevibacillus choshinensis and its utilization as an easy-to-remove affinity peptide. Bioscience, biotechnology, and biochemistry. 2023. 87. 9. 1029-1035
  • Atsuhiro Shimada, Tomitake Tsukihara, Shinya Yoshikawa. Recent progress in experimental studies on the catalytic mechanism of cytochrome c oxidase. Frontiers in chemistry. 2023. 11. 1108190-1108190
  • Yohko Yoshida, Ippei Shimizu, Atsuhiro Shimada, Keita Nakahara, Sachiko Yanagisawa, Minoru Kubo, Shinji Fukuda, Chiharu Ishii, Hiromitsu Yamamoto, Takamasa Ishikawa, et al. Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Scientific reports. 2022. 12. 1. 14883-14883
  • Traci E LaMoia, Gina M Butrico, Hasini A Kalpage, Leigh Goedeke, Brandon T Hubbard, Daniel F Vatner, Rafael C Gaspar, Xian-Man Zhang, Gary W Cline, Keita Nakahara, et al. Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 10. e2122287119
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MISC (18):
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Patents (1):
Education (4):
  • 2009 - 2013 Osaka University Graduate School of Science, Doctor's program Department of Biological Scineces
  • 2007 - 2009 Osaka University Graduate School of Science, Master's program Department of Biological Scineces
  • 2006 - 2006 Tohoku University Graduate School of Agricultural Science Bioscience and Biotechnology for Future Bioindustries
  • 2002 - 2006 Tohoku University Faculty of Agriculture
Professional career (1):
  • 博士(理学) (大阪大学)
Work history (4):
  • 2021/04 - 現在 Gifu University Faculty of Applied Biological Sciences Associate Professor
  • 2017/04 - 2021/03 Gifu University Faculty of applied Biological Sciences Assistant Professor
  • 2013/06 - 2017/03 University of Hyogo Graduate School of Life Science Specially Appointed Assistant Professor
  • 2011/04 - 2013/03 日本学術振興会 日本学術振興会特別研究員(DC2)
Awards (2):
  • 2020/08 - Protein Science Society of Japan Young Scientist Award O2-activation and unidirectional proton-pump mechanisms of cytochrome c oxidase elucidated by X-ray structures of its catalytic intermediates
  • 2018/09 - The Biophysical Society of Japan Early Career Presentation Award
Association Membership(s) (3):
THE BIOPHYSICAL SOCIETY OF JAPAN ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY
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