Rchr
J-GLOBAL ID:201701006554221644   Update date: Apr. 02, 2024

Ishiwata Ryo

イシワタ リョウ | Ishiwata Ryo
Affiliation and department:
Job title: 助教
Other affiliations (1):
  • 横浜市立大学  循環制御医学   共同研究員
Research field  (4): Pharmacology ,  Pathobiochemistry ,  Clinical pharmacy ,  Physiology
Research keywords  (10): neutrophil surge ,  Transcription Factor EB ,  lysosome ,  vascular calcification ,  arteriosclerosis ,  elastic fiber ,  Three dimensional arterial model ,  Prostaglandins ,  vascular smooth muscle cell ,  aortic aneurysm
Research theme for competitive and other funds  (11):
  • 2023 - 2028 Elucidation of mechanisms and functions of the postnatal neutrophil surge
  • 2022 - 2025 転写因子TFEBの分解誘導機構の理解に基づく血管石灰化治療の検討
  • 2021 - 2022 Examination on TFEB-targeted therapy for vascular calcification
  • 2021 - 2022 Elucidation of the Lysosome Dysfunction that leads to vascular calcification in CKD
  • 2019 - 2022 Prostaglandin E3-oriented regulation of chronic inflammation
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Papers (19):
  • Ryo Ishiwata, Yuji Morimoto. Hyperphosphatemia-induced degradation of transcription factor EB exacerbates vascular calcification. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2022. 1868. 3. 166323-166323
  • Taro Hiromi, Utako Yokoyama, Daisuke Kurotaki, Al Mamun, Ryo Ishiwata, Yasuhiro Ichikawa, Hiroshi Nishihara, Masanari Umemura, Takayuki Fujita, Shota Yasuda, et al. Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation. Arteriosclerosis, thrombosis, and vascular biology. 2020. 40. 6. ATVBAHA120314297-1573
  • Yokoyama U, Arakawa N, Ishiwata R, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Matsumoto M, Koizumi N, et al. Proteomic analysis of aortic smooth muscle cell secretions reveals an association of myosin heavy chain 11 with abdominal aortic aneurysm. American journal of physiology. Heart and circulatory physiology. 2018. 315. 4. H1012-H1018
  • Shujiro Fujita, Utako Yokoyama, Ryo Ishiwata, Rika Aoki, Kenji Nagao, Daiki Masukawa, Masanari Umemura, Takayuki Fujita, Shiho Iwasaki, Shigeru Nishimaki, et al. Glutamate Promotes Contraction of the Rat Ductus Arteriosus. CIRCULATION JOURNAL. 2016. 80. 11. 2388-2396
  • Ryo Ishiwata, Utako Yokoyama, Yasuhiro Ichikawa, Daisuke Kurotaki, Shota Yasuda, Motohiko Goda, Shinichi Suzuki, Munetaka Masuda, Tomohiko Tamura, Yoshihiro Ishikawa. EP4 Signaling in Smooth Muscle Cells Attracts Inflammatory Immune Responses in the Aorta. CIRCULATION. 2016. 134. Suppl 1. A13042
more...
MISC (9):
Books (1):
  • 生理学用語ハンドブック
    丸善出版 2024
Lectures and oral presentations  (11):
  • Mechanisms of the Postnatal Neutrophil Surge and its Potential Roles in the Establishment of Postnatal Homeostasis.
    (The 101st Annual Meeting of The Physiological Society of Japan 2024)
  • Hepatic neutrophil pool possibly contributes to the postnatal neutrophil surge
    (The 100th Anniversary Annual Meeting of The Physiological Society of Japan 2023)
  • 高リン酸血症による転写因子TFEBの 分解促進は血管石灰化を促す
    (筋生理の集い 2022)
  • Transcription Factor EB Regulates Hyperphosphatemia-induced Vascular Calcification
    (the 98th Annual Meeting of The Physiological Society of Japan 2021)
  • Inhibition of PGE2-EP4 Signaling as a Potential Future Therapeutic Strategy for Abdominal Aortic Aneurysm
    (2016)
more...
Education (3):
  • 2013 - 2017 Yokohama City University Graduate School of Medicine Cardiovascular Research Institute
  • 2011 - 2013 Waseda University
  • 2007 - 2011 Waseda University
Professional career (1):
  • 博士(医学) (横浜市立大学)
Work history (3):
  • 2017/09 - 現在 National Defense Medical College Department of Physiology Research Associate
  • 2017/04 - 現在 Yokohama City University Cardiovascular Research Institute Collaborative Researcher
  • 2014/04 - 2017/03 Japan Society for Promotion of Science Doctoral Fellow
Committee career (1):
  • 2023/03 - 現在 The Physiological Society of Japan council member
Awards (3):
  • 2016/11 - American Heart Association Travel Award for Young Investigators
  • 2014/08 - European Society of Cardiology Top Score Poster Award
  • 2013/05 - The 7th TAKAO International Symposium The Excellent Poster Award
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